HsaINT0107869 @ hg19
Intron Retention
Gene
ENSG00000092054 | MYH7
Description
myosin, heavy chain 7, cardiac muscle, beta [Source:HGNC Symbol;Acc:7577]
Coordinates
chr14:23901848-23902436:-
Coord C1 exon
chr14:23902293-23902436
Coord A exon
chr14:23902005-23902292
Coord C2 exon
chr14:23901848-23902004
Length
288 bp
Sequences
Splice sites
5' ss Seq
TACGTGAGT
5' ss Score
7.77
3' ss Seq
TGCTCCTTTTCTATCCCCAGACC
3' ss Score
10.93
Exon sequences
Seq C1 exon
ACAGTGACCGTGAAGGAGGACCAGGTGATGCAGCAGAACCCACCCAAGTTCGACAAAATCGAGGACATGGCCATGCTGACCTTCCTGCATGAGCCCGCGGTGCTCTACAACCTCAAGGATCGCTACGGCTCCTGGATGATCTAC
Seq A exon
GTGAGTGCTGCACCTGGCCCTACGTTGGGATCTCTGTTCTTGCTCCATCCATGTCCACCCCAGGAGCCAAGAGTGTCTTCTGTTTGTGTCTAGGCAGGGTTACACTCTAACCTCGTCCCAACATCCTTGGTTCAATTCCAACACTCTGGGGACTGGCATTACTCAGATTGAGTGCATGCAGAGGTTTTCCTTTCTCTTCTTTCTCTCCTGGGATCTTTCTCTAACTCCCAAAATCACCAGCCCTCCCCCTTCGCAACTGGCAAGTCACTGCTCCTTTTCTATCCCCAG
Seq C2 exon
ACCTACTCGGGCCTCTTCTGTGTCACCGTCAACCCTTACAAGTGGCTGCCGGTGTACACTCCTGAGGTGGTGGCTGCCTACCGGGGCAAGAAGAGGAGCGAGGCCCCGCCCCACATCTTCTCCATCTCCGACAACGCCTATCAGTACATGCTGACAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000092054-MYH7:NM_000257:4
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.146 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0273614=Myosin_N=PD(16.7=14.6),PF0006316=Myosin_head=PU(4.1=58.3)
A:
NA
C2:
PF0006316=Myosin_head=FE(7.6=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
ACAGTGACCGTGAAGGAGGAC
R:
TGTACTGATAGGCGTTGTCGG
Band lengths:
292-580
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)