HsaINT0107891 @ hg19
Intron Retention
Gene
ENSG00000078814 | MYH7B
Description
myosin, heavy chain 7B, cardiac muscle, beta [Source:HGNC Symbol;Acc:15906]
Coordinates
chr20:33578807-33581028:+
Coord C1 exon
chr20:33578807-33578924
Coord A exon
chr20:33578925-33580904
Coord C2 exon
chr20:33580905-33581028
Length
1980 bp
Sequences
Splice sites
5' ss Seq
GCGGTGGGT
5' ss Score
6.6
3' ss Seq
GCTCTGCCCTCCTTTCCCAGGTA
3' ss Score
11.12
Exon sequences
Seq C1 exon
GGGTCATGGATGCCTTCTTGGTGCTACACCAGCTGCGCTGCAATGGGGTCCTGGAGGGGATCCGGATCTGCCGCCAAGGGTTCCCCAACAGGTTGCTCTACACCGACTTCCGGCAGCG
Seq A exon
GTGGGTGACCCCTTCCCCCTGCCTGCTGCTCCAGGTGGAGGCCTGAGGGGCTGGGCAGGACACACATATCAGAGCCCAACAGACGGTCCCCTGTCTGGAGGGGGAAGCAGGGACTGTGAGGGGCCTGGCCAGGTATCCCAGCAAGACATGGGGGTGGCTCAGACCTGGCCGGGGACTTGGGGAGAAGTGAATAGGCTTGGGGCAAATAGTGGAGGTGGAGCCTACAGGCCTCGCTGATAAGCTGGACATGGAATTCTGGATGCAGAAAAGACGAATGATTTCTAGTTTTGGGAGTGAGCAACCTGGGAGCTACCAGTGGTAGATTTACTGAGCTACAAAAACAGGGTTTTTTGATTTGGAGGAGAGGTGAAGGGATACTGGTTTGAGCTCTGTTTTGCGTGTATCAGGTTTGAAATGCCTCCAGCAGACATCCTAGAAAAGTCATGGGGGAGATTGGGATTATCAATCTGGAGCTCAGGGCAGCGGGCAGAAAGGATGCAGATTTGGGAGTTGAACGAGAATCATGTGGACGAGGCTTCATGAGACACCTGGCACATAGCAAGCACCTGGGCAGTGCTGCCAGCTCCTCCCCGTTCCCTCAATGGGCAACAAGCATCCATCGTTCCTTCTCCCTCCAGAAGTCATGGTGTCATCCACACTATCCTTTGTAAACAGAGGTTCACACAGATACCATACACGCACACACACGCATGGTGCTGTGACCTTGTTTTTTCTAACAGTCTGGCCTGGAGATCGTTCCTTATCCCCAGGCGTATGCCTGCCATCGTCATCCGTTTTTCTTGGCTGTGAAACATCTCACAGTCTGGTGGACTGCATGCTTTGTTTAATGAGTCCCCCTCATGAGGGGCCTTCACAGCGTGGCTGTAGCCCACCTGACCCACACAGCCCTGTGCATGTGTCCACTTAGAAGTGGGCAGGCTGGGAGCCCTGGCTCTTTTGCATTAGAATTTCCCCCCAAATGGGCTGGGCGCGGTGGCTAACGCCTGTAATCCCAGCACTTTGGGAGGCCGAGGCAGGCGGATCACGAGGTCAGGAGATCGAGACCATCCTGGCTAACACGGTGAAACCCCATCTCTACTAAAAATATAAAAAAATTAGCCGGGCGTGGTGGCGGGAGCCTGTAGTCCCAGCTACTCGGGAGGCTGAGGCAGGAGAATGGCCTGAACCCGGGAGGCAGAGCTTGCAGTGAGCAGAGATCGTGCCACTGCACTCCAGCCTGGGCGACAGAGCGAGACTCCGTCTCAAAAAAAAAAAAAAAAAAGAATTTTCCCCCAAATGTTTCTTCAGTGATAGGGTACAGCATGTCACCTTCTACTAATATTTTTTGCCTTTAAAAAAATTTTAAAAATAGTGCATGCCTTCTGTAAAAAGCCTCTTTAAAAACTTAATGAATGCATTTAAAATCCCCCCAAGGTTGTGTTTTTTTTTTTTTTTTTGAGACGGAGTCTTGCTCTGTCACCCAGGCTGGAGTGCAGTGGCAGGATCTTGGCTCACTGCAACCTCTGCCTTCTGAGGTTCAAGCGATTCTGCAATTCTTCTGCCTCAGCCTCCCGAGTAGCTGGGATTACAGGCGCCCGCCACCATGCCCCACTAATTTTTGTGTTTTTAGTAGAGATAGGGTTTCACCATGTTGCCCACGCTGGTCTTGAACTCCTGGGCTCAAGCAATCCACCCGCCTTGGCTTCCCAAAGTGTTGTGATTATGGGCGTGAGCCACCGCACCCAGCCAACCCCCCAGGGATTTTAAGTGGAGTGTCCCTAGTGTCCCAGTGTGGTGACGCATCCCTGGCCCCCTTGTTTGGCATGTGCCCTGCTGGAACCTCTGCACCAGCCTCGGAGAGGCCCAGGAACGAGTCCCCTGCTACCCACACGAGCCTCCTCAGTCCCTGACTTCCCCATTCTCAGTGGCCTGTGCCCCATACCCAGCCCTCTCCTGACCAGCTCTGCCCTCCTTTCCCAG
Seq C2 exon
GTACCGTATCCTGAACCCCAGTGCCATCCCGGATGACACCTTCATGGACAGCAGGAAGGCCACAGAGAAACTGCTGGGCTCGCTGGACTTGGATCACACCCAGTACCAGTTTGGCCACACCAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000078814-MYH7B:NM_020884:24
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0006316=Myosin_head=FE(5.7=100)
A:
NA
C2:
PF0006316=Myosin_head=FE(6.0=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GGGTCATGGATGCCTTCTTGG
R:
GTGTGGCCAAACTGGTACTGG
Band lengths:
238-2218
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)