HsaINT0107906 @ hg19
Intron Retention
Gene
ENSG00000078814 | MYH7B
Description
myosin, heavy chain 7B, cardiac muscle, beta [Source:HGNC Symbol;Acc:15906]
Coordinates
chr20:33587594-33588492:+
Coord C1 exon
chr20:33587594-33587709
Coord A exon
chr20:33587710-33588095
Coord C2 exon
chr20:33588096-33588492
Length
386 bp
Sequences
Splice sites
5' ss Seq
GAGGTGTGT
5' ss Score
6.14
3' ss Seq
ATGCCACCCTCCTCCCATAGGCG
3' ss Score
10.11
Exon sequences
Seq C1 exon
GGGGCCCTGGAGCTGGAGGAGACCAAGACGCTGCGGATCCAGCTGGAGCTCTCCCAGGTCAAAGCAGAAGTGGACCGGAAGCTGGCAGAGAAAGACGAGGAGTGCGCTAACCTGAG
Seq A exon
GTGTGTCCATCCTTCTCCCGTCCCCACCTCCCGAGAGCAGAAGGGGAGGGAAGCAGTGTGTACTCTGCTCTCTAGTCTGTCCCTCCCATGGGACTTTGAGGTCCGGGTTGCTGTCTCCATTCTAGCTGTGAACCTCGGAGATGCTAAAGGACTTGCCCAAAGTCACACAGTGGGGGTGGAGCCAGTCAGTCCACCTCTGTCTGCCTGGGCCTCACTCTTGTCCATGAACTTGCTCTGATGGGCCACAGGCAGTCACAAGAGACTTTAAATCGGGGAGGGGTGACTCATTTGTTCTCAAAATGGGTTCGTTTCCAACGGTCCTTGGGCATTTGTAAGGACAGGTATGCCCTTACGAGACCCCCTTTCATGCCACCCTCCTCCCATAG
Seq C2 exon
GCGCAACCACCAGCGAGCTGTGGAGTCCCTGCAGGCCTCCCTGGATGCAGAGACACGGGCCCGCAATGAGGCGCTGCGGCTCAAGAAGAAGATGGAGGGTGACCTCAACGACCTGGAGCTGCAGCTGGGCCATGCCACCCGTCAGGCCACAGAGGCCCAGGCTGCCACGCGGCTGATGCAGGCACAGCTCAAGGAGGAGCAGGCAGGGCGGGACGAGGAGCAGCGGCTGGCAGCTGAGCTCCACGAGCAGGCGCAGGCTCTGGAGCGCCGGGCCTCGCTGCTGGCTGCGGAGCTGGAGGAGCTGCGGGCTGCCCTGGAGCAGGGCGAGCGCAGCCGGCGACTGGCAGAGCAGGAGCTTTTGGAGGCCACCGAGCGCCTCAACCTTCTGCATTCGCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000078814-MYH7B:NM_020884:38
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.359 A=NA C2=0.705
Domain overlap (PFAM):
C1:
PF0157614=Myosin_tail_1=FE(4.4=100),PF045827=Reo_sigmaC=PD(3.3=12.8)
A:
NA
C2:
PF0157614=Myosin_tail_1=FE(15.4=100),PF0003816=Filament=PU(22.4=44.4)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GGAGCTGGAGGAGACCAAGAC
R:
GTGGAGCTCAGCTGCCAG
Band lengths:
352-738
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)