HsaINT0108761 @ hg38
Intron Retention
Gene
ENSG00000197535 | MYO5A
Description
myosin VA [Source:HGNC Symbol;Acc:HGNC:7602]
Coordinates
chr15:52376347-52379733:-
Coord C1 exon
chr15:52379625-52379733
Coord A exon
chr15:52376559-52379624
Coord C2 exon
chr15:52376347-52376558
Length
3066 bp
Sequences
Splice sites
5' ss Seq
CTGGTGAGA
5' ss Score
7.54
3' ss Seq
ACAATTTCTTCCAAAAATAGGAC
3' ss Score
7.07
Exon sequences
Seq C1 exon
GTGGACTTACCAAGAATTTTTCAGCCGCTACCGTGTCCTAATGAAGCAGAAAGATGTGCTGAGTGACAGAAAGCAAACATGCAAGAATGTGTTAGAGAAACTGATACTG
Seq A exon
GTGAGAATGATTTCGCTTACCGTCATCTGAGCAGAAGGCCTTGTGGTTCTGACCTTGGAAAGCCCCGGGAACTTTTGTATAACATTTTACTAGTCCAGATCATTTCGGGGTGGGATCAGAGAGGGGCACACTACTGTGTTTAGGATGCTGGAACTAGCGAGGATGATAGTCCACCGTCAGGAGGCAGAGCTGTGAGGCCTGGACCCACATTTGAAACACATTCTTCTTAGACAGCTTGATTATTATTGATAAAAGTGTACCTAGTACTTACATCTAGAAGACACCAGGCCAAATGCTGTGTGATTAAGAAAAAATAAAGCTTGTTCTCAGGTAATATAGTCTTACTTGGAAAGTAATACTTTTTAAAGACGAGTATAATATTTAACTGTAGTGTCTATATCAAATGCTGAATGAATGGAACAAGAAATCAGGGGATGACAAAGCGACGTCCAGCTATGGGAAGGAGAGATTTCATCAAAGAGGTGTGTTTTGAGTCAGGCCCTGAGAATGGGTAAGGTTATGCAAAAATGGAAGGAGACTATTATAAGAGGGAGTAAGAGCAGGGTAAGCATAGGGTTTGCTCAGAAAACAGTTTTTTGCAGTGTGAGATTTGTGTATGGGACAGTAGAGAAATGGTTAGGAAATGTAGGTTGGTGTTACAGAGAGTCTTGCAGACCAGGCTAAAGAGTTCTCCAACTTTACTGTGACCTGGAATGCTTGTTAAAATACAGATTGCTGGGCCCCGCCATCAGAATTTCTGATTCAGTAGGTCTGAGGTTGGGCCCAAGAATTTGTATTTCCCGGGTGATGCCGATGCTGTCTGAGGACTATATTTTGAGAACTACTGATCTTGGTCTTAGAGAATTAAAGATTCATGAAAAGTTTTTAAAATAATATTTTCACTTGGTTAACACTATCCTAGATGGAGTACCTCACTTTGAGCTAATTGATCATAATTACTAGCTGTGAACTAAATGTGATGCCTTTTTTTTGTTAATAATATTTTTTCCTTGAAAGAGCTAAGGCCACTTCCTCAGCAATGCTTTTTTTTTTTTTTTAACTGGGGCTTTTTGAGTTTGCCCCAATTCCCTTCTTTTTTTTTTTTTTTTGAGACAGTCTTGCTCTTTCACCCAGGCTGGAGTACAGTGGCATCTCGGCTCACTGCAACCTCCGCCTCGTGGGTTCAAGCCATTCTCCTACCTCAGCCCCCCCAGTAGCTGGGATTATAGGTGCACACCACCACACCCAGCTAATTTTTGTATTTTTAGTAGAAACAGGGTTTTACCATGTTGGCCAGGCTGGTCTTGAACTCCTGACCTCGTGATCTGCCCGCCTCGGCCTCCCAAAGTGCTGGGATTACAGGTGTGAGCCACTGCGCCCAGCCTGCCCAATCCCCTTCTAACCTGTGTTCAGGTGGGAATGTAGAGCAGAAAGTAGGAACAGGCCTATTCCTGGTCCTCTCACCCAGGCCATTTCAGGCCTGGATCAGGGCTTTGTGGGAATTTAGTTAGGCAGAGGAGGCTGAAAGATGGAGGCAGGGTTGGTGTGAGGTGTGAAGCGGGATGCGGGTAAGGACCACTTTTCTAGCTAGGTTTCCAATGTAAACTTTATTGATTTAAATTGAAATAATTGTAGATTTTTTAGATATATGTGGATGTGTCAGATTTTTTGGTTTCATATATGAGATAATATGAGATATCTACTCATAGGGAAAAATGATTTTCTCTGTTTTCCCTTAGACTTTCAGATCACATGGCCAAGCATGGTGGCTCACGCCCTTAATCCCAGCACTTTTGGAGGCCGTGGCGGGCGGACTGCTTGAGGCCCAGCGTTTGAGGCCACCCTGGCCAATATGGTGAAACCCTGTCTCCACTAAAAATACAAAAATTAGCTGGACGTAGTGGTGTTTACCTGTAATCCCAGCTACTCAGGGGGCTGAGGCAGGAGTGTCGCTTGAACCCAGAAGGCGGAGGCTGCAGTGAGCCGAGATTACAGCACTGTACTCCAGCTTGGGAGACAGAGCGAGACTCATCTCAAAAAAAAAAAAAAAGAATTCCAGGTCACAGTAATGATTCTTACATATAAATTCCATTCTTTGATGCAAGAATGATTAATGATTTGCATACTTCTAGATAAGGTGAATCACAATGTAATATAAATTATTATGTTTTTGTAAAAGGAGTTTGAAAGGATTTTTTTTTTTTGAGACGGATTCTTGCTCTGTTGCTAGGCTGGAGTGCAGTGGCGCGATCTTGGCTCACTGCAACCTCCACCTCCTGGGTTCAAGCAATTCCCCTGCCTCAGCCTCCCAAGTAGTTGGGAATACAGGTGCATGCCACCATGCCCGGCTAATTTTTTGTATTTTAATAGAGACAGGGTTTCACCATGTTGGCCAGGATGTTCTCGATCTCCTGACCTCATGATCCGCCAGCCTTGACCTCCCGAAGTGCTAGGATTACACACGTGAGCCACTACACCCGGCCAATTTGTAGGATTTTAAACATATTTATGGGGTTTTGTTAGTTTGTTTTCAGATATTATTGATAAAGCCAAGAGCTAACTGTTTAGAAACATAACTCAATATGAATACCCAAGGATTTTGGTTTTTGGTTTTTGAATTTTATTTCATAAACGTTTCTTCCTGCCTTATTCTTCACACTGGTGTTTTTGTCCCTTCAGCTTCTCATGGAATATACAGCCCGCTGTAATCCTTACAACCTGGGTCAGTCAGAGAGAGTCAGCATCTCCATTTCCTTGAGATGTTTAAAACACAAACAAGCAAATAATAACTGCCTATAACCCACAACCAAGTTTTGGGCCTCAGATAATAATTCCAGGTAGAATAATTCTGGAAAATAACTCTTAAACTGCAGTTTTTCTTAAAATCCCTTCTATTTGCTCAACTTGCATAGGATTAAAAATCTGGCTCCATTAGTTAATTGTGATGTAGCCCAAGTTTTAGCTAATAGAGTCATTCCTTTACTGATTCTGCTTTTAGACATTTTTTCTTTTAAATTTCACTTATATGATTATTATTTCTGAATATACAATTTCTTCCAAAAATAG
Seq C2 exon
GACAAGGACAAATACCAGTTTGGTAAGACAAAGATCTTTTTCCGTGCCGGTCAAGTGGCCTATCTAGAAAAATTGAGAGCTGACAAACTGAGAGCTGCCTGCATCCGGATCCAGAAGACCATCCGAGGGTGGCTGCTGAGAAAGAAGTACCTACGCATGCGGAAGGCAGCCATCACCATGCAGAGATACGTGCGGGGCTACCAGGCCCGATG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000197535:ENST00000399231:18
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0006316=Myosin_head=FE(5.3=100)
A:
NA
C2:
PF0006316=Myosin_head=PD(2.1=19.7),PF0061222=IQ=WD(100=29.6),PF0061222=IQ=PU(81.0=23.9)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development