HsaINT0108849 @ hg19
Intron Retention
Gene
ENSG00000128833 | MYO5C
Description
myosin VC [Source:HGNC Symbol;Acc:7604]
Coordinates
chr15:52517636-52521510:-
Coord C1 exon
chr15:52521330-52521510
Coord A exon
chr15:52517730-52521329
Coord C2 exon
chr15:52517636-52517729
Length
3600 bp
Sequences
Splice sites
5' ss Seq
AAGGTAGAG
5' ss Score
6.38
3' ss Seq
CCGTCATTGCTGTGATTCAGACA
3' ss Score
5.15
Exon sequences
Seq C1 exon
GCTTCTTGAAAAAAGTTTTGAACTGAAAACACAAGACTATGAGAAGCAGATTCAGTCTTTGAAAGAAGAAATTAAAGCTCTCAAGGATGAGAAGATGCAACTCCAACACCTGGTGGAGGGGGAGCACGTCACTTCTGATGGCTTGAAGGCGGAAGTGGCCCGCCTGAGCAAGCAGGTCAAG
Seq A exon
GTAGAGCGGCTCTCACGTTCAGCCCCGCCCTCTGGTTACGTCATTTGATTGCAATTCCAAGTTCCCACAGATTAGACAGCTAAAAGCATCTGTGTAAAGGCCACAGGCAACTGGAGCCTGATTCCTTCAGTCCTTCCAACTGTGCACCTCCAGGCTGCCTTTGATTTAGCAATCATTGTATTCCATATTTTAAAAGTCAACTTTCTAACTTTTTTGAAATTACATTTATGTAAAGTTATTTAAATATGTCGATGTAGAGAATACTCCCAAATTAGACTGTAAATTGAGGTGAATCCTTATTATATAATCCATCACTATAAATCTATAAACACCTGCATTAAAGTTAAGTTACCTTATTATCAAAATCTTTCATTTAAACTGTTATTAGAAAATTTACTAAAACAATTATCCAATGCACAGTGTGGTGAATGTAGTTAATAAGAGCATATTGTACATTCAAAATTGCTATGAGTAAATCTTAAATGTTCTCACCACAAAAAATGACAAGTATTTGAGGTGATAACATGTTAATCAGCTTGAATTATTCCACAATATATTCATAAATTATAACATCAATAAAGCTATAAATTTTCAATGGTAGAAATTTTTAAGTAAATTTTTATAAAGCTGAGAAGGAAAAATCACATAGAATTTTTAAAACTGCATAATGATATATAAAAATATTGTTACCTGCCGGGCACGGTGGCTCAGGCCTGTAATCCCAGCACTTTGGGAGGCCAAGGCAGGTGGATCATGAGGTCAGGGGTTCTAGACCAGCCTGACCAACATGGTGAAACCCTGTCTCTACTAAAAATACAAAAATTGGCTGGGCGTGGTGGCAGGTGCCTGTAATCCCAGCTACTCAGGAGGCTGAGGCAGGAGAATTGCTTGAACCTGGGAGGCGGAGGTTGCAGTGAGCCGAGATCGCGCCACTGCACTCCAGCCTGGGTGACAGACCGAGACTCCGTCTCAAAAAAAAAAAAAATTGTTACCTGTATCTATCATTAAAAATATATAAATATTCCTGGGCAATTTAATAAAATGCTCTAGAGAAAAATGAATGAATGGATGAAGTAATGATCCATGCTTGGACAATCAAGGCTTAAGTGAATTGTTTCCCTACCAGAAAAGTTAAACCTGAGTGTACCTACGTTCTTAAATGTAAGACATTTCATCATTAAGTTGGAAAGCTTTTAAGCTTCTACTAAATATGTGAAATACATATTAGTAGAGTATTTGTAGGATTATGGAAATAGTCTCTGTAATTGTCATGAACTAGCCATGCGTGGTTTAGAAGAGCTTTTGGAATTGCATCCGGGTGGCCACTGAATTCCACAACTGAAGTGTCTGTCTTTTCTGGGCCCCGTCCCCTATTGTTTAAAAGTAGGAGGTCAGACCACATGATCAGGAAGGGTCACTTTCATTCCTGTGACTGCTTCACTCTTAGCAGCCACATGAGCCTGATGTCAGTCAGTCTGTGGGAGTCCTGTCATCTGGCTGAGGTCTGAGGTCTGTATCTTAAATGTAGGAACTTGTGAGACTGCGCTTGCAGAGAGGTACCAGTAGGTGTCACTCACTTCCTCTTTGGTAGCTAAGACTGGTTCACTCTCCAATGTGATCCATTAAGATTACTTGGGGCTGGGCACGGTGGCTCAGGCCTGTAATCCCAGCACTTTGGGAGACTGAGGTGGGCGGATCACGAGGTCAGGAGATCAAGACCATCCTAGTTAACACGGTGAAACCCCATCTCTACTAGAAAAAAAAAAAAAAATTAGCCGGGCGAGGTAGCACACACCTGTAGTCCCAGCTACTCGGGAGGCTGAGGCAGGAGGGTCGCTTGAACCTGGGAGGTGGAGGTTGCAGTGAGCCGAGATTGCACCACTGAACTCCAGCCTGGGTGACAGAGTGAGACTCCGTCTCAACAAAAAAAAAAAAAAAAAAATTACTCTGGGTTTTTGTGTTTTGTTTTTTGGGTTTTTTTTGAGACAGAGTTTTGCTCTTGTCACCCAGGCTGGAGTGCAATGGCACCATCTTGGCTCACTGCAACCTGCCTCCCAGGTTCAAGCGATTCTCATGCCTCAGCCTCCCAGGTAGCTGGGATTACAGGCATCTGCCACCACACCTGGCTAATTTTTTTTTGTATTTTTAGTAGAGACAGGGTTTCACCATGTTGGCCAGGCTGGTCCTGAAGTCCTGACCTCAGGTGATCCACCCGCACTAGCCTCCCAAAGTGCTGAGATTACAGGCGTGAGCCACCGTGCCCAGCCTACTCTGGTTTTCAAAGAAAATAACTCATGATCATCAAGTTATATGTGTTATAGTCAGTCTTAAAAGCCTAAGTAAATGCAAATCTGACTTGGAACATTTACTGAAACATTACAAAGAAAAGCATGGCCTTCAGGATTTGGATAGTCCTGAGTCCCCCATAAACCTGGCATGTGACCCTGAACGTGCCAGTCAGCCTTCAGTTAAATGTAGCTGCTGTTTGCTAATTGAGAAAAGATCACTCTACTTACCTCATAGGCCTGTTAGGAGGATTAGGTCTTCTAGGTAAAGTGCTCAGCACATATCAGTTTGATTCTCCTGCTTACTCTCTGTAGAAACAGGGGCTGGAGCCCTTAAATACTCAGGGTAACTGAAAAAATATCAAGGAGAGTTTATTCACCTCTGCTGTCCCTGAAAGTCCTTATATCTCCCTCAGATACAAAGCAAAAGCACAGACCTGTGATTCTTATTCAAGCTGAGCTCACAAGGGAGAATAAAGGCAGAATACTGCCTCTTCCCCACAACCAGAGCTGCCCAGGCCACCTCCTTCCCAACAGCCAGCTAACTCCCAGACCTCCTGGACTCACCAGTCTCTGCCACTGCTCCACATCTAAGCTGAGCTGAAGCCAAAACCCACAGTTATGAAGGTGGCAACTTTGCCCATGTCCTTGCACTCAATATTTTATTATCCATTAAAAGAGAATTTTAGCCCGTGATTTTACCTTTCTCAGTCTTCCCCCTGTCCCACCCCACCCCAAGCTTATAGTAGGTATTTTTTTTTCTTTATGTAACAGGGAAGTTAATTTTTTTTTTTTTCGAGGTGGAGTTTTGCTCTTGTTCCCCAGGCTGGAGTGCAATGGTGCAGTCTCAGCTCACTAAAACCTCTGCCTCCCGGGTTCAAGCGATTCTCCTGCCTCAGCCTCCCAAGTAGCTAGGATTACAGGCGTCTGCCACCATGCCTGGCTAATTTTTGTATTTTTAGTAGAGATGGGATTTTACCATGTTGGTCAGGCTGGTCTCAAACTCCTGAACTCAGGTGATCCACCTGCCTCAGCCTCCCAAAGTGCTGGGATTACAGGTGTGAGCCACCATGCCTGGCCCAGGGAAGTTAATTCTACTGATACAACCCATTAGATCTGGCATTTTGAGTAGTTAAGCATGCTTCAAGGCCAAGCTGTGTAGGCAGTGATGGTTTAACAAGATTTTAGCTAAGAAAGAAACTGCAGTGAGGATGTCTTGCATAGACACGCAACGCTGTAATTGTGTTCCCTTTGTCTTATATAAAGCATAATCGTTGTTTTTTCTTTACCTGATTCCGTCATTGCTGTGATTCAG
Seq C2 exon
ACAATCTCTGAGTTCGAAAAAGAGATAGAACTACTTCAGGCACAGAAGATAGATGTGGAGAAACATGTGCAGTCACAAAAACGGGAAATGAGAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000128833-MYO5C:NM_018728:25
Average complexity
IR-C
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.066 A=NA C2=0.250
Domain overlap (PFAM):
C1:
NO
A:
NA
C2:
NO
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal3)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)