HsaINT0108853 @ hg19
Intron Retention
Gene
ENSG00000128833 | MYO5C
Description
myosin VC [Source:HGNC Symbol;Acc:7604]
Coordinates
chr15:52513359-52515921:-
Coord C1 exon
chr15:52515741-52515921
Coord A exon
chr15:52513453-52515740
Coord C2 exon
chr15:52513359-52513452
Length
2288 bp
Sequences
Splice sites
5' ss Seq
ATGGTATGG
5' ss Score
6.63
3' ss Seq
TTTCTAATTCTTCTCTAAAGATG
3' ss Score
6.87
Exon sequences
Seq C1 exon
TGTTTTGGAGAGCCATTTCCAGTCTCAGAAGGATTGCTATGAAAAGGAGATTGAAGCTTTGAACTTCAAAGTGGTGCATCTCAGTCAAGAAATCAACCACCTGCAGAAGTTATTCAGAGAAGAAAATGACATCAATGAAAGCATCCGTCATGAAGTTACCAGGCTAACATCAGAGAACATG
Seq A exon
GTATGGTCTCAGCCAGGGGCCCCAGTCGTGGCCATCATACTAGAGTTGTTCTTTGTCAGTGGCGTCAAATTCAGTTTCTTGGCAGTAAAAGAGTGGATATAAATTACTTTTTCCAGAAGTGAAATAACTTGGTCTGGTGATTAAACTATAAAATGACTGCAGACCAGAGAGCACTCTGATACAAGAGTGTGTGTGTTCACCACAGGATGGCTGCAGGCGCTGTGATTGTCTGTGTGTGCGCGTAAGTGTGTATGTTTTAAAGCCTGTATATTTAAATCAAGCCCTAACCCCTTGGAAAGTGACCACAAAATTGAAGGGTAGCTCTTGAGACAGGAGTGTGTCAGAAGGCCAGTCCTGCTCATGCCTGAAATCTCACCTTTTTTTTTTTTTTTTTTGAGATGAAGTCTCACTCTGTTGCCCAGGCTGGAGTGCAATGGCATGATCTCAGCTCACTGCAACCTCCGCCTCCCAGGTTCAAGCAATTCTCCTGCCTCAGCCTCCCGAGTAGCTGGGATTACAGGCGCCCACCATCACGGTCAGCTAATTTTGCATTTTTAGTAGAGACAGGGTTTCACTATGTGGGCAAGGCTAGTCTCGAACTCCTGACCTCGTGATCCGCCTGCCTCAGCCTCCCAAAGTGGCATAAGCCACCGTGCCCGGCCTTCAAATCTCACCTTTTCAAGGGCTTCCTCTTCCATGACGTGCATTCCTAGCCACTGCATTTGTCTCATTCTTTCTTCCAACTCATGCCTACTGGCCTGGAGAAATGCTTTAGGAATCTCCTCATTCAAAAAGCCATCTCTGTCTTAACCCCACACTGCTGTGGCCATCACCCATTTCTTTGGGGTCTTAGTCAGACTTACAAAGACCCTCTAGGCATACTTCCTCCGCACACCTCCCATTCACTGCCCACCACCCCATTCTGTCGTGTGTCCCCACCACTGGCTGACTCTGCCTGCACAGAGCTGAGCACTAAGGGTTCCTTTGCACCCTCATCTTACTCAGTGTCTCAGCAGCCTCTGGCGATGCTAATCTTGCCCTCTCTGCCTTGTTCTCTTGGCTTCCAGGACGCCCCGCTCTCCCAGCATTCTTGTCCCGCCTCACTGGCTGCTGCTCCCCTACTTCCTTACTACCCCCTCCTCTCCCTAAACTGAGAGTGTTAGGAAATCTCGGGGCTGTAGCAGCAGTTGAGGACCAGGGGTGGACACAGGGAACGGTAGTGGGGGACCTTTACATCTTTGTTTATTCCTTGGATGAAACTTTAATGAGGAATTTGCAGTGAGACCCAATTGCACATTCAAACAAGTACAGATGCTCCTCAGCTTACCATGGGGCTACGTCCCAATAAACCCATCGTATGCTGGAAGTATTGTATTGTAAGTTGAAAATGCATATAATACACCTGACCTACCAAGCATCGTAGCTTAGCCCAGCCTGCCTTAAACGTGCTCAGAATGCTTACATTAGCCTGTACTTGGGCAAAATCATCTAACACAAAGCCTATTTTTATAATAAAGTGTTGAATGTCTCATGTAACTTATCAAATACTATACTGAAAGTGAAACACAGAATGGTTGAATGGGTACTTGAAGTATGGTTTCTACTAAATGCATATCACTTTCACACCATCACAAACTCGAAAAATAGTAAGTTGAGCCATCGTAAATCAGGGGCTGTCTGTATTCTTCATTTAGACTTCAGAGGCCTGGATCTCAGCCACTCAGTTTTAAAATGAGCATGTTTATAAACTTGGGGAAGGAAAAAAAACCCTGTTTTAACCTAACTGGGGGTGGAGGCGATGGACATGTAAAGAAATATACAGATAGGGACAAAGGATTGAGAAACTTACCGGGTGATTCCAGACCTCCACTAACAGAGCAGTGCATGTCCTTGAATTCAAAAGTAGCAGTGGGACCCTTTGAGATGGCTTTTCCTGTTCCTAGATGAGGAGACGATGGCTCTGGGCTTGGACCAAAGACGCTGGCTGCCATTTCTTCACCTAATTCCTCCCTCAACTCAGCATAGGATTTCTATACATGTACACATCCTTCTCTCCCTGTCGTAGCTGTGTGAGAACTGCTTCCTCTGAGCATACTGGTGTTTCCTGAGACTATATAGGTTTTGAGGTTAAAAAAAAATGTTAATCCAGTCTAATGTCGTGGCTAGCTCTTTTACACAGCTATCTGTTCTGCAGGCTGAACACCAAGATAGTTCAGTTTGCTTCTAAGATTTTAAAGTTCATAGATAAAAGTATTTTATATTCTAATATTTCTAATTCTTCTCTAAAG
Seq C2 exon
ATGATCCCAGACTTTAAACAGCAAATTTCAGAATTGGAGAAACAGAAGCAAGATCTTGAAATCCGCCTGAATGAACAAGCTGAGAAAATGAAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000128833-MYO5C:NM_018728:29
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.139 A=NA C2=0.394
Domain overlap (PFAM):
C1:
PF131661=AAA_13=PU(26.8=91.8)
A:
NA
C2:
PF131661=AAA_13=FE(14.8=100)
Main Inclusion Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)