HsaINT0108912 @ hg19
Intron Retention
Gene
ENSG00000137474 | MYO7A
Description
myosin VIIA [Source:HGNC Symbol;Acc:7606]
Coordinates
chr11:76909540-76910863:+
Coord C1 exon
chr11:76909540-76909666
Coord A exon
chr11:76909667-76910579
Coord C2 exon
chr11:76910580-76910863
Length
913 bp
Sequences
Splice sites
5' ss Seq
CAGGTGAGG
5' ss Score
10.07
3' ss Seq
CTGGCCTTGATCTCCTTCAGGGA
3' ss Score
8.89
Exon sequences
Seq C1 exon
GCCCCAGTCTCCCCAAGAACGACGTCATCGTGGCCGTCAACTGGACGGGTGTGTACTTTGTGGATGAGCAGGAGCAGGTACTTCTGGAGCTGTCCTTCCCAGAGATCATGGCCGTGTCCAGCAGCAG
Seq A exon
GTGAGGAGGCCCGCATGGAGATGCAGACAGACAGAGGGGAAGGAGAGGGGCTGGAGCTTCCCTGCGGGTCACAGGAAGTGAAGAGGCATGAAGTGGCCTGCCTGGTTGCACGTGATTGGGCAGTTTGTGCCGCACTGTGCAGACCCCTCTGGCACCTCCTAGTGGAGGGATGGGCTTGGGCTTTACAGCACATTAAGGCTGTTCTGAGACAGGAATGGGCTGTCAGGACAGGCAGGGGCAGGTGAGTGTGTACAAAAGAGCTTGACCTGGGGGTTCAGGGGACTGAGTAGCACTCACTCTATGTCTTCATTCCTAAAACAGGAGTCTTAATACTTTTCTCGCATAACAGTGGTGGGGAATGAATGCAATAATAGATGGGAGAGCTCTTTATAAACTGCAAAGTGCAGTGCACATAGGTGGAATGGTGGGGTGGGTTGCTGGGATTGACTGGCTTTCCCAGCAGTGCAGTGGCTCCCTCCTCCACCATCTGGGGCTTGTAGCAGTGTCTTTGGGTTGTGTCTGATATGGGCTGGAGTCAGACTGTGTCCAGCACTGACCAGACACATGCCAGGCACACAGGATGCAGTAGTGACAAGATAGTCCTTGTCCTCTTGGATCTTCAGTCAAGAGAGGAGACAGACATTGAATAGGCCATTTTAAAGCATGGTATGATCAGGGCTGTGGGAGGGCAGGGAGGACTTCCTGGAGGAAGTGGCATGTAGGTTGAGATTTAAAGGGTGAGTAGGAATTAGACAGGCAAAGGAGAAGTAGGCCGGGCCACTGTGGGTCTCCCTCTGGGCCATGCCTGACTCTGGCCAGGCCAGCTCTGACTTAGCCTGAGATGTGTCTGAGCTGGGCCACGTCTCCCACTGGTTGGGGCATGACTGACTCAACTGGCCTTGATCTCCTTCAG
Seq C2 exon
GGAGTGCCGTGTCTGGCTCTCACTGGGCTGCTCTGATCTTGGCTGTGCTGCGCCTCACTCAGGCTGGGCAGGACTGACCCCGGCGGGGCCCTGTTCTCCGTGTTGGTCCTGCAGGGGAGCGAAAACGACGGCCCCCAGCTTCACGCTGGCCACCATCAAGGGGGACGAATACACCTTCACCTCCAGCAATGCTGAGGACATTCGTGACCTGGTGGTCACCTTCCTAGAGGGGCTCCGGAAGAGATCTAAGTATGTTGTGGCCCTGCAGGATAACCCCAACCCCG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000137474-MYO7A:NM_000260:34
Average complexity
IR-C
Mappability confidence:
NA
Protein Impact
No protein impact description available
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.021
Domain overlap (PFAM):
C1:
NO
A:
NA
C2:
PF146041=SH3_9=PU(13.6=8.3)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
Associated events
Conservation
Rat
(rn6)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GGACGGGTGTGTACTTTGTGG
R:
CTGCAGGGCCACAACATACTT
Band lengths:
353-1266
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)