HsaINT0108917 @ hg38
Intron Retention
Gene
ENSG00000137474 | MYO7A
Description
myosin VIIA [Source:HGNC Symbol;Acc:HGNC:7606]
Coordinates
chr11:77205462-77206202:+
Coord C1 exon
chr11:77205462-77205617
Coord A exon
chr11:77205618-77206096
Coord C2 exon
chr11:77206097-77206202
Length
479 bp
Sequences
Splice sites
5' ss Seq
GAGGTACAG
5' ss Score
6.62
3' ss Seq
TGCCCCTGCTGCCTTTTCAGAAA
3' ss Score
10.01
Exon sequences
Seq C1 exon
GTACAGCGAGGAGCGGGGTTGGGAGCTGCTCTGGCTGTGCACGGGCCTTTTCCCACCCAGCAACATCCTCCTGCCCCACGTGCAGCGCTTCCTGCAGTCCCGAAAGCACTGCCCACTCGCCATCGACTGCCTGCAACGGCTCCAGAAAGCCCTGAG
Seq A exon
GTACAGCGGCCACCAGGGGCAGGGACAGACACTGGGGCGGGCTCCTGGCCACGCGGGGCTTGTGGGATGAGCCCCTTGGGGATGAGGACCACATAGCAGTTGGGCCCACCCCTGGGGTACCTCAACTGCCAGCTAGACGGAGGTGCGGATCCTGCAGCTGCTCAGGATGCAGCTGGAGAGTCCGGCTGCTCGGGAGTGCTCAGCCCAGAGCTCCCAGGCTATCGGGTGGGCACAGACACCTGGGCCCACTTCATACTCTCCGAGGGCACTTGTGTTCTTCACTTTGCTGGGCCTCTCCACACCCATCGTCCCATTTTACAGATGAGGAGCTCAAGGCTCTGGGAGACTCAGTGGCCGGTCACATCATAGGAAGTGGCAGGCGGGGATCAGAACTGGGGTTGTCTGCCTCCAAGTGTCCCGGTCCCCTGGTCTCCACAGTCCCACGCACATGCCCCCTGCTGCCCCTGCTGCCTTTTCAG
Seq C2 exon
AAACGGGTCCCGGAAGTACCCTCCGCACCTGGTGGAGGTGGAGGCCATCCAGCACAAGACCACCCAGATTTTCCACAAAGTCTACTTCCCTGATGACACTGACGAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000137474:ENST00000409709:40
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0078412=MyTH4=FE(48.6=100)
A:
NA
C2:
PF0078412=MyTH4=PD(15.9=47.2),PF093795=FERM_N=PU(8.5=22.2)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GAGGAGCGGGGTTGGGAG
R:
TCGTCAGTGTCATCAGGGAAGT
Band lengths:
254-733
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development