HsaINT0108931 @ hg19
Intron Retention
Gene
ENSG00000137474 | MYO7A
Description
myosin VIIA [Source:HGNC Symbol;Acc:7606]
Coordinates
chr11:76883794-76885960:+
Coord C1 exon
chr11:76883794-76883931
Coord A exon
chr11:76883932-76885801
Coord C2 exon
chr11:76885802-76885960
Length
1870 bp
Sequences
Splice sites
5' ss Seq
ATGGTGAGT
5' ss Score
10.13
3' ss Seq
CTTGGCTGTGTGCCTGGCAGCTG
3' ss Score
9.01
Exon sequences
Seq C1 exon
GGCGCCGAGACCAGGAAGCGCTCGCCCACACTTAGCAGCCAGTTCAAGCGGTCACTGGAGCTGCTGATGCGCACGCTGGGTGCCTGCCAGCCCTTCTTTGTGCGATGCATCAAGCCCAATGAGTTCAAGAAGCCCATG
Seq A exon
GTGAGTGGCCCTGGCCTGGGGTTGGCGGGTGGCGGCTAGGGTGACGTGGAGGAGCTAGGTCAAGAATAAGGTAGGGTGGGAGTGAAGGATGTGAGACTTTGTCCCTTTGGGGAATGGGGGGCACCCCGGGAGCTTACAAAACAAGGCCCCCTATTTATTGGAGGCAGCAGGTGCCTTGGAAAGAGCCTAGACTCTGCGGGGGGTTGCAGCAGGTTCAGATCCTGCCTCTACCATGTACAAGTGGGCGACTGCAGACAAAGCAGTTTCTTCTCTTATGCCTCAGTTTCCTCATAGATGGAAACGGGACTGACCGTATCTACCTCCTAAGGCTATTCCATGCAGTAATGCTTGCAGATGCCCACACCCAGCAAGTGCCCAGTGATTGGCAGCTGTGGTTCTTGCTGGGGCTGCTTCTTTGAAAGTCCCCTTCTCCTTTGGCCCAGCTCAACCACCACCTCCTCCTGGAAGCCTCCCCCATCTCTTCAGCTGGTTGGGATATCCTCATTCTTGACTTTTCTGAATAACATTTGTTGGGCCCTTTCTGTGTGCCCAGCATAGGCTGGATGGTCAGTCCACAGCCTCCTTCAACCTTCTCAAACAGCCCGTGAGAAAGGGACTGTGCTGGTCCCAGGTTAGAGATGCGGGACTGGGGGCTCAGGGAGGTTAAGGGGCTCAGGCTGGGGCCACCTCGCTGCGAGCCCTCTCCTTTCGCAGCACAGGCTCTGGGAGGGTTGTTTACCCAGAGGCCTGCAGGGAGGCACAGGGGGAAGCTGGGGCCTCGGGATCTGGGGAGGGAAGGAAGGCCGGGGAAAGTGGCCCGGAGAGAGAGGAAACAGTCTCCGGAAGCTGACAGGCTGCAAGACCGTCCCCTCCTGCTGCCTCCTGCCTGGAAAACATGTCCCAGAGTGGATGAGGCCTGTCCCCTTTAGGACTCAGGTCTGCAGGGGCCTGAGGGTCGCAGAGGGCTCCAGTGAGCTCTCCCTCTAATGCAGGGGGTGCAGGGGACTGACACCAGGGCAGTCGGGCACAGTCTTCCCTGGCTCTGAAGTGGGACCCTTCCCTCGGCCCAGTCCTCAGCATCTGTGGACTGGGCCTTGGCAATAGCCTCCTCAAGGGTCTCCTGCCTCCCTTGCCTCCTGTCCTGCCTCCCCTGGCCCCCAGTGACATTGTTCTCAAATGCAGACCTGGCCCAGTCTCTCCCTGCTCTAAAACTTCCCTGGCTTCCAGCATCCATGGATGAGGCCCTCACAGAGCCCCACAGCCTCACAGCCCAGCACCTGCCTTCTACTCTTTCTCCCCAGCCCCTCCACCAACCAAACCCCAGGGCCCTTTGAAAAATGTGCCTCTTCCTTAAGGCAGCTAGAAAGTTGTCTGAATAACCGCAGATCTACAATACCTGCAACGTGAAAGGTCCTCCCTGGGGCTGTGCAGAGCACCCCTCACCTGCACAGCCATAACTTGGCCTGGACGAGCCTCTCTAGCTCCCTCAAGATTCCCAGCAAAGTCCTGCGCTTTCAGGCTTCCAAACCTTTGCACAGGCTCACCCCCTCCAGCCTTGGAATACTCCCCCTCCTGTCAGGGTTAGGGTGATAAAGACGCCTCCTCCATGAAGCTCCCCACTTGGGTGTCCCAAGGGGAATTAATCTGTCTTCTCTGTGCTCCCAAAGCACACAGCTCCACCACGACAGGCCTCACTTTATGCTCTTTTGTGGATTTGAGCTGCAGATCCCGGTGCCTGTCCCAGCTTTGCTCCTCCCATGCCGTGTGGACTTGGCCTTTCTGAGCCTTTGTCTGGGTTGGTCAAGTGCACAGCAGGGCTGCCTCCCAGCAGGAGCCTTGGCCCTGATGCCCTTGGCTGTGTGCCTGGCAG
Seq C2 exon
CTGTTCGACCGGCACCTGTGCGTGCGCCAGCTGCGGTACTCAGGAATGATGGAGACCATCCGAATCCGCCGAGCTGGCTACCCCATCCGCTACAGCTTCGTAGAGTTTGTGGAGCGGTACCGTGTGCTGCTGCCAGGTGTGAAGCCGGCCTACAAGCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000137474-MYO7A:NM_001127179:16
Average complexity
IR-C
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0006316=Myosin_head=FE(6.8=100)
A:
NA
C2:
PF0006316=Myosin_head=FE(7.8=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GGCGCCGAGACCAGGAAG
R:
CTTGTAGGCCGGCTTCACAC
Band lengths:
294-2164
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)