HsaINT0108932 @ hg38
Intron Retention
Gene
ENSG00000137474 | MYO7A
Description
myosin VIIA [Source:HGNC Symbol;Acc:HGNC:7606]
Coordinates
chr11:77174756-77175464:+
Coord C1 exon
chr11:77174756-77174914
Coord A exon
chr11:77174915-77175371
Coord C2 exon
chr11:77175372-77175464
Length
457 bp
Sequences
Splice sites
5' ss Seq
CAGGTACAG
5' ss Score
8.68
3' ss Seq
GTTCCCCATCCTCACTCCAGGGC
3' ss Score
8.91
Exon sequences
Seq C1 exon
CTGTTCGACCGGCACCTGTGCGTGCGCCAGCTGCGGTACTCAGGAATGATGGAGACCATCCGAATCCGCCGAGCTGGCTACCCCATCCGCTACAGCTTCGTAGAGTTTGTGGAGCGGTACCGTGTGCTGCTGCCAGGTGTGAAGCCGGCCTACAAGCAG
Seq A exon
GTACAGGGCTGAGTGCACAGAGGGCAGGAGGGGAGGGTCCCAGCTTTGGCTGGGCAAGGGTCCCAATTTTCTTATCAGGACCATGGGCGGGGCTTGACATCTGCTTGACCTCTCAGGTGCAGCACGGAAAATTGGGGTTCAGGTATTGGAATGCATCAGTGGGCTTCAGTTGCCATGTTCAGCTGGTGAGGACTTCACACATGGTGGTGTAAGGAACAAGACCAGGGCTGCCACGCGGGCCCTGGATGTCAGTTGTGAGAAAGGGTTTTGCAATCATACCATCCAGCTGAGCTAAGGAGAAAACTGGGGCTCAGAGAAGGCAGGACCCAGCTGAGGTCACACTTCGAGTCAGGGGCAGAGCTCGGGAAGAGCCCTGCCTCTCAGCCTCGGGGACACTCCGGAGGCCTTCCCACTGGAGAGGCTGTCCATTCCCTTGTGTTCCCCATCCTCACTCCAG
Seq C2 exon
GGCGACCTCCGCGGGACTTGCCAGCGCATGGCTGAGGCTGTGCTGGGCACCCACGATGACTGGCAGATAGGCAAAACCAAGATCTTTCTGAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000137474:ENST00000409709:17
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0006316=Myosin_head=FE(7.8=100)
A:
NA
C2:
PF0006316=Myosin_head=FE(4.5=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GTTCGACCGGCACCTGTG
R:
TCAGAAAGATCTTGGTTTTGCCT
Band lengths:
248-705
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development