HsaINT0108940 @ hg38
Intron Retention
Gene
ENSG00000137474 | MYO7A
Description
myosin VIIA [Source:HGNC Symbol;Acc:HGNC:7606]
Coordinates
chr11:77181951-77182600:+
Coord C1 exon
chr11:77181951-77182154
Coord A exon
chr11:77182155-77182423
Coord C2 exon
chr11:77182424-77182600
Length
269 bp
Sequences
Splice sites
5' ss Seq
CTGGTAAGG
5' ss Score
9.68
3' ss Seq
ACATGCGCGCTCTGCCCCAGGCA
3' ss Score
6.95
Exon sequences
Seq C1 exon
GACCTGGAGCGAGGGCGGAGGGAGATGGTGGAGGAGGACCTGGATGCAGCCCTGCCCCTGCCTGACGAGGATGAGGAGGACCTCTCTGAGTATAAATTTGCCAAGTTCGCGGCCACCTACTTCCAGGGGACAACCACGCACTCCTACACCCGGCGGCCACTCAAACAGCCACTGCTCTACCATGACGACGAGGGTGACCAGCTG
Seq A exon
GTAAGGCCTGCCTGTCACTAGGTCACTGCTGGGTGGGGCCAGGGCTGGGGCTATGGACTCTGCTGCTGGTGGTGGCCGTAGGTGATGAGGGTGGTGGGTCCCTGGGGGCCAGGGACCAGGTCTGACTATAGTCTTCACTGCGGTGCCCAGCCTGAGGGCTGACCATGCGGGAGGGGGTGTCTCCAGCCCACTCCCCAAACCGCCAGGTCATTTTGACAGCTTTAGCAATGTCCTCCGCTCTGGCCTCTGACATGCGCGCTCTGCCCCAG
Seq C2 exon
GCAGCCCTGGCGGTCTGGATCACCATCCTCCGCTTCATGGGGGACCTCCCTGAGCCCAAGTACCACACAGCCATGAGTGATGGCAGTGAGAAGATCCCTGTGATGACCAAGATTTATGAGACCCTGGGCAAGAAGACGTACAAGAGGGAGCTGCAGGCCCTGCAGGGCGAGGGCGAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000137474:ENST00000409709:24
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.485 A=NA C2=0.305
Domain overlap (PFAM):
C1:
NO
A:
NA
C2:
NO
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CTGACGAGGATGAGGAGGACC
R:
GCAGCTCCCTCTTGTACGTCT
Band lengths:
297-566
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development