HsaINT0108980 @ hg38
Intron Retention
Gene
ENSG00000169994 | MYO7B
Description
myosin VIIB [Source:HGNC Symbol;Acc:HGNC:7607]
Coordinates
chr2:127632246-127633363:+
Coord C1 exon
chr2:127632246-127632401
Coord A exon
chr2:127632402-127633257
Coord C2 exon
chr2:127633258-127633363
Length
856 bp
Sequences
Splice sites
5' ss Seq
GAGGTGAGC
5' ss Score
8.7
3' ss Seq
GCACACGCTGTCCCCCTCAGGAC
3' ss Score
7.64
Exon sequences
Seq C1 exon
GCACAGCGAAGAGCGGGGCTGGCAGCTGCTGTGGCTGTGCACGGGCCTCTTCCCGCCCAGCAAGGGGCTGCTGCCCCATGCCCAGAAGTTTATAGACACTCGGAGGGGGAAGCTGCTGGCCCCCGACTGCAGCCGCCGAATCCAGAAGGTCCTGAG
Seq A exon
GTGAGCCCAGTGCCTCCAGCCCCCAGCATTGGCCCTGGGCCCGCAGACCTGGGATGCTGTGGGGCCTGGCCAGCCTTCCAGGAGCTCATGGTCCTGGGAGGACTCTCCAGAAGCCAGTGTCAGCTTGGCAGGCAGGATTGGGCCCCGAGCTGCCAGAGAAGAGGGTGGAGGGTGAGGCCCAGGAGGGTCAAGAGAAGGCTCAGTCATAGCCACCAGCTCCCCTGCCCCACCACTGCCCAGCAGTGGCACAGAGGCACTGCCTGAGGGATAGAGAGAAACCTGGATGCCCCAGCCCAGGCCCTCAAGGCTGAGGTCAGAGGCCCATCCTTCCAAGTCCATGCGGCCTCCCTCATCCGCCCACAGCCGTGAAGCTCTTCCTTGGCCGTCTTTGCTCTCCCCCACCCCTCCTGCCTCCTCTGGCTTGGCCTCCTGTGGCCGTGAGGAGGGCAGGTTGACTGTAGGAGTGGCCATAATTTCAGTGGCAGCCGTGGTCACAGAGAGAGGTGGGCGCCCCATAGAGGCCCTGCCAGAGTCCCTGGCCCCTGCCCGATGCCCCTGTTGTGCGAGAATAAGAATACTGCCAGCCTTTCCTGCCGGCGCCTTCCCGGGAGCCCCTGGCCTGGCCCTTCCCCGTGTGTGCCCCAGGCTTTCAGGCACAGCTGCACCATCACTACCTCTGAGGCCGCGTGGAGCCAGGGGCAGCCCCCAGGACATGCGAGGGGCTGGAACCACCCCAGTGATGGTCACTGGGGTTTTCTTTTGTTTCTGGCACATGGTTTAGGGCCCACATCGGGGCTGGGGCATGGGTGAGGATGAGGGTGGGGGTGGCACCTGCAGCACACGCTGTCCCCCTCAG
Seq C2 exon
GACGGGGCCCCGGAAGCAGCCCCCGCACCAGGTGGAGGTGGAGGCCGCAGAGCAGAACGTCTCCCGCATCTGCCACAAGATCTACTTCCCCAATGACACCAGTGAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000169994:ENST00000409816:37
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.057 A=NA C2=0.361
Domain overlap (PFAM):
C1:
PF0078412=MyTH4=FE(49.1=100)
A:
NA
C2:
PF0078412=MyTH4=PD(16.0=47.2)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GCTGCTGTGGCTGTGCAC
R:
CTCACTGGTGTCATTGGGGAA
Band lengths:
238-1094
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development