HsaINT0118546 @ hg38
Intron Retention
Gene
ENSG00000110048 | OSBP
Description
oxysterol binding protein [Source:HGNC Symbol;Acc:HGNC:8503]
Coordinates
chr11:59593604-59594255:-
Coord C1 exon
chr11:59594010-59594255
Coord A exon
chr11:59593725-59594009
Coord C2 exon
chr11:59593604-59593724
Length
285 bp
Sequences
Splice sites
5' ss Seq
CAGGTAAAG
5' ss Score
9.65
3' ss Seq
TTGAACCTGATTTCTTCAAGGTG
3' ss Score
7.11
Exon sequences
Seq C1 exon
GTAAACTTTAATGAGCCCTTGTCCATGCTTCAGCGCCTTACTGAAGATCTGGAATACCATGAGCTGTTAGACCGAGCTGCAAAATGTGAGAATTCTCTAGAACAGCTCTGTTATGTTGCAGCTTTCACCGTGTCCTCCTACTCCACTACTGTCTTCCGCACCAGTAAGCCATTCAACCCACTGCTTGGGGAGACCTTTGAGCTGGACCGATTAGAGGAGAATGGGTACCGATCCCTCTGTGAACAG
Seq A exon
GTAAAGGAACCTCAGAACCATAACGCATTTCCTTTCTGAAGAAAGAGATGATTTTTTGGTTAATCCCCTGGGTCTTATGTTTGCAGAAATTCTAGTCCCTGTCATCCCAGCTTTTATTCTTTTTCTTCAGAACGTCAGCGTTGGAGACCCTGGAGGTTCTGGGATTCACCTACTGTTGTGGGTGTAAAAACGTCAAGTGTGAATTTTGGTGTTTCTCACCAATTTATAGGCAGTATCTTTTTCTTCTCCTTTCTGCCGTCTTAATTTGAACCTGATTTCTTCAAG
Seq C2 exon
GTGAGTCATCATCCCCCTGCTGCTGCGCACCATGCTGAGTCCAAAAATGGCTGGACATTGCGTCAGGAAATCAAAATCACCAGCAAGTTTCGAGGCAAATACCTCTCCATTATGCCCCTCG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000110048:ENST00000263847:8
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.085
Domain overlap (PFAM):
C1:
PF0123713=Oxysterol_BP=FE(21.5=100)
A:
NA
C2:
PF0123713=Oxysterol_BP=FE(10.6=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GCTGTTAGACCGAGCTGCAAA
R:
CGAGGGGCATAATGGAGAGGT
Band lengths:
305-590
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development