HsaINT0119110 @ hg19
Intron Retention
Gene
ENSG00000183378 | OVCH2
Description
ovochymase 2 (gene/pseudogene) [Source:HGNC Symbol;Acc:29970]
Coordinates
chr11:7723704-7725336:-
Coord C1 exon
chr11:7725245-7725336
Coord A exon
chr11:7723877-7725244
Coord C2 exon
chr11:7723704-7723876
Length
1368 bp
Sequences
Splice sites
5' ss Seq
CAGGTAAGA
5' ss Score
10.77
3' ss Seq
TTACTCTTTGCTTTCCATAGAAA
3' ss Score
9.87
Exon sequences
Seq C1 exon
GTATCTCTGAAACAAAGGCAGAAGCATATTTGTGGAGGAAGCATCGTCTCACCACAGTGGGTGATCACGGCGGCTCACTGCATTGCAAACAG
Seq A exon
GTAAGAAAGGCCTAGCCCATGAGTGAAGACCACACCACCATTTCTTCTCCCTTGGAATCATCAGCAATAACCCTATTAAAACATGGACCTGTGTGATAGGTGAGTATTGGTTTAACAGATGAATATCCTAATTGCATGACACAAATGGGGCTGGGTGACATTGTCAGATGGCACTTGGTAGATGACATATATTCTTTTCAGAGGTAAAATTCGTTTTTACTTAAAATAACTGGAAGTTAATAATAGCATCCAAGTCAGAAAAAAAAGAGCATTACAAAGAAGGATTTGTGAAAGTTTTCTTCTAGTTTTCTTAAATTTCAGTGAAAAAATATCTAGTTCATTATGCATCTGAAGAAATGGATAAAAGAAAACAAAGGGAGACCAGTAAAGTAGAAAGTAGGCTCCCTGTCTTCCTTCCCATTGATCCTGCCTCTCTGGGACTCAACCCAACAACTTCCCTTTACCCACTTTCTTGTGTGATCCAAATATCCTATTATTGACAGTGTTCTGGGCGTATACTAGGCTGTAATCAAGATCATGTTCCCATATAGTCATTCTTTCATTTCAAGTCTGCAAACATTTCCTGGATGTTTACTTTGTGCTAGATACCAAAGGTACCAAAATGACTAAGACATGATTTCTGCCCCCAGAGAGTTGACTCTTCTTTTAACAAGAGTCAACCGATCATCTCACAGCAATGTGGCAAGTGGTAGGTAAGAGAGACATTATGTGTTAAGTTAGGTACCTAATTTGGCCAAGAGTCAGGGAAGTATACCTAGAGAAAACATGCCTTTTTCAATTTTGTATAGAAGCATCACTTCTGGGAATGAAGCGTCTCAAAGGATGGCAAGCTGAAGTCTTTATATATCTCAATGCATCCCACCAAGTTCCTTTCAGAGAACATTAGTTAGTTATAATGCAGTCTGTGCCTTATAATATATACTAAGCATAGGATCTCTGACATTGAAGTAGCATACTTACTGGGAATCACAAATCATTCCCAAAGGGTCTCACTGATATTAGGTCAGGTCAACCTCCCAGGGTAGCTGAATAAAGTCCCCTATAGCTGTAGAGCCCTGAACTACAATGTATGTGCCTCTCTAGATATTTTCAAATAACATTGCAAAGTATTAAATTCATCATATCCTTGGCTATATATGAACCCACTCTTCACTAGTCCTCTACTGGAAGTTGGAATCTCTGCATTTTTTTCTAACAGTGTTGGAATTATTCTCACTTTCTCTGCTCAGCAGCCTCACACCCCATATTATTTATCCATATCATTTTAAAGAAGCTAGTGTGTCAACCATTGCAACTGTACTCAGAGGCACAATGAAATTCATTCATTTTACTCTTTGCTTTCCATAG
Seq C2 exon
AAACATTGTGTCTACTTTGAATGTTACTGCTGGAGAGTATGACTTAAGCCAGACAGACCCAGGAGAGCAAACTCTCACTATTGAAACTGTCATCATACATCCACATTTCTCCACCAAGAAACCAATGGACTATGATATTGCCCTTTTGAAGATGGCTGGAGCCTTCCAATTTG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000183378-OVCH2:NM_198185:3
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0008921=Trypsin=FE(12.3=100)
A:
NA
C2:
PF0008921=Trypsin=FE(23.9=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Rat
(rn6)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GTATCTCTGAAACAAAGGCAGAAGC
R:
GCTCCAGCCATCTTCAAAAGG
Band lengths:
254-1622
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)