HsaINT0120122 @ hg19
Intron Retention
Gene
ENSG00000100767 | PAPLN
Description
papilin, proteoglycan-like sulfated glycoprotein [Source:HGNC Symbol;Acc:19262]
Coordinates
chr14:73735265-73741347:+
Coord C1 exon
chr14:73735265-73735431
Coord A exon
chr14:73735432-73739202
Coord C2 exon
chr14:73739203-73741347
Length
3771 bp
Sequences
Splice sites
5' ss Seq
CAGGTAGGA
5' ss Score
9.79
3' ss Seq
TCTCCCCTGTCGTTCTGCAGCAC
3' ss Score
10.74
Exon sequences
Seq C1 exon
GAACGGGCTACCTGTGCAGGCTGATGGCCACCGTGTCCACCAGTCCCCAGATGGCACGCTGCTCATTTACAACTTGCGGGCCAGGGATGAGGGCTCCTACACGTGCAGTGCCTACCAGGGGAGCCAGGCAGTCAGCCGCAGCACCGAGGTGAAGGTGGTCTCACCAG
Seq A exon
GTAGGAAAGGTCTATATCCGGGGATGGGAAGGACATTCCCCAGTAGATTTACTGGTTCTCAAGGGCTGGCTCTGCAGTCTGAGGGACTCTGGTTTGAATCCTGGCTCACCCTGCCAGTTGCTGGTAGTGTGACTTGGGGCAAGGGGCTTACCTTCCTGAGCCTCATTTTCCTCCCGTCTACAGTGGGGCTGCTCCACCACCTGAGAGGGCTGTAGTGGAGATGAAGGAAATGATGCTCTGCTGGGCCCCTGGAGATAGCTTAATAGACATTAATGCATGCAGGACATTCAGACTCACCGATTTTGAGACATATGACTGACTGGAATTTCATTATAAAACTTAAAACTTAAGGCAGACCACTAAAATCTGTCCACTCTAATCCACTCTAAACCACTAAAATCTGGCCACTTTATGGCCGTTTGACCATATAACCCAGAAAGGAAAGGGCAGGGATTATCATCACCATTTTACAAATGAGACAGGTATGCAGAGAGCGTAAGTGGTGTTTCCACCGGTCACACCGCAAATGTGGCCTACCTGGGACTAGAGCCCATGTCTTTTGACTCCCCATGTTTTTTTTTTTTTACCCCCACGAAATTACTATACTTGTACCTAAGTGGAATCTTACTTGCATCATTTGATATTTGATATTGTAGCCTTACCTCCTCTAGCTACTACTCTATCATACTTCAACAAATCCAAATTGCCTGTAAGATGCATTATTTTTGTACCAAGAAAAAAATGCTGCCAGTGAAACGACACAATTCTGATACCATCAATTAGGATGCAAACCAACTTGAGAGATGTGAAAATAAGTGCATATCAGAACTGATGAAACAGATTGTGGTTCAGAGTTCACACTTACAAGAGATATGTTCAAATAAGCAGGAGGGAAAGGGGGACAGGGCTTTGCTCGTCCCCCAGCCTGTGCTTCCTTGTGTCCTTGGTTCTTGTTCACGGAGGGACTGAAGACAGAGTGGTACCTCGGGCCAAGCTGCCAATTCTCACAGGCCTGATACAGACCTTGGGGGAGTATGCCAGGCTCGGAGGTGCCAGGGCCCTTCCTGCCTGGTCTTCTGGGCATTCCTGACAATCAGGGCTGCAGCGCCATGCCAGGAGCACGGTTACACTCAGAGGGGCAGGCCTGGCTGCTTCCTGGCTGCCAGGCTGAGGGTGGAGACTGGCCAGTACTAGAAGTTGAAGGTCTGGCTGAAATGTTGCTTTGTGAGTGGGACTGACTTGTCGGCTTCCTGTCTATGATCTCTTTAGAGATCGCCTCCCCAGGGCCCAGCTCAGTGCTTGGCATCACTAGGTGCTCATGTTGTGGCTGGAAATGTTGTCCAGCGGCTTTTTTCTCACCTGTTGCTCGGCGAGCGGGAGGGAGGGTTACAGGGTTCCTTCCTGCCGCTTCGCCAGCCCGCCGCCTTGACCTCTGTCCGGGGCCTCGCTCGGCCCACCGTCTCGCTCCGCCCACTTGGCCGGGCAGGCTGCGCTCCGCTGACCCGGATCCCGCACTCGTGGCGGCCCCGCGCTCAGCGCACGGCACAGGCGGCTTCCGCACTGGGTGCTAACGTATAGACAAGGGGAACATGGTGGCGCCCGAAAACTCGGAGATGCCAGCAACCGCGGAGCCCCAAGGGGGTGTTACAGGGACAAATGTTCCCGCCGCTCGCAGCTCGGTGAACGGGAGCGTTAAAACTCGTTCTTCCCTCCATTCCCTCCTGCTCACCCAGCTACAAAAGCCGCGACACTCAGATACATGGTGACTAAGTGCCTGCCTGCACAATGATGGAGTTACATTGGCGAAAGCACCACACTCCAGGGACTACTTTTCACCTGTATCATGTCCAGAAAATTGACCTTGTCTACATAATAACCAAATCAAGGCTGTGTGACAAAGCAAAATGCAGATTCACAGTGAGAGAACTGTCAAGAGGACCTAGACATTATGTTTGCGATTAGCTCCAGATGGGATTACATGGAAAACCAAACTACAATGAGAAACTTGCCTGATACCTGGTCACCACGCTGAAATGGCCTGAGATGTGTGTCCCAGATGGGACAGACATGGCCTCAGTCTGGCCACTCTCCTCCGGTCCTCTGCTGGCTGCTCTCACCTGTTCATTTTTTGTTGGGTCATACGGTGTGCGGCTGCCTGACCCTGCCCTACTCATGGTTGGGTGGCACATTGAATTTCAGTGTTAGCACCAGGGTAGGAGGCCTTGGGGTGGTCAGGCTGAGGTAAAAGGGACATAGCTCTACTGGGAGGACTTCTCAACATCGCTGTGAAGTAGGTTGCTGTTGCTGTTATTAGTCCCATTTCACAGATGAAGAAATGTGCATAAAGGGCTTAAGCAACTTGCCCAGAGTTACCCAGCTGGCAAGTGGCAGAGCCCGGATTGAGCCCGGGCAGTATGGGTCCAGAGCTGGTGTGCTTAATCACTATGCTGAGTTCCCACTATGATGGGTCTTGGGCTGTACCAGCTCAGAGTTGATACCAAAGTTACAGATTTTTAGAAACAATATGCATTAATGGCTTTGTTATCTATATAAATTTAGGTAGGTAATAGTCTGGTTATACCAATATACCAAACGTTTGTAAGGTTGTTCGCTGCTAGGTACAGTCTTTTAGTGGTATTTTGTGAGTAAACAAGGGGAGAGAGAAAGATAAGCTTTCTCTGGCTGCTTGAGGTCTGACTTCAGGGAAGGTACCACTCTGGTCTAAGTCAGCTGAGTTTTAAGAACCCCTTCCAGAAGAGAGATGAAGCAGTAGAATGAAATTTTTTTTTTTTTTTTAAGACAGAATCTTGCTCTGTCACCCAGGCTGGAGTGCAGTGGTGTGGTCTCAGCTCACTGTAACCTCTGCCTCCTGGGTTCAAGCGATTCTTCTGCCTCAGCTTCCCGAGTAGCTGGGACTACAGGGGCACGCCACCATGCCTGGCTAATTTTTGCATTTTTAGTAGAGATGGGGTTTCACCATATTGGCCAGGCTGGTCTCAAACTCCTGACCTCGTGATCCGCCCGCCTTGGCCTCCCAAAGTGCTGGGATTACAGGCATGAGCCACCACACCCAGCTGAATGAAACTTAATAGGGAGTTATGAGATACAGACGTTCCTAGTAAATTCAGAGGGAGAGAAAACAAGGGCTTTGCTTTGTTCTCAGTGTAGTTAGTATTAGAGCCACCGTTAACAGGACTGTTTTCCTATTACCTTGTCTAATATGCATTGCTTCCTCTGGGGAAAGTGAAAAACTGGAAGGATGAGGACCCAGGTGACTAAGATAAGCTGGTGATATTGAAGGGACAAAACTTTGATGGTTGGAGGAACCCAGCAGAGAAAGGGAAAAGATAAGAGCTCTTGCTAACTCAAAATTTTACTTGGGGCTGATCCTACCTGCTCTCCCAATCCAGAGGCAAGAACAGTTGTCATTTAGTAATTCAGGTCTCAAACATAAGGAGTTAACTTCAAGAGATGTTTAATTATCCAGTCAATAAATATTTGGGAGTCTAGGAAGAGCTATTCAGTGGGCTGAGGCCACAAATAATAATGGGAGGACCACTGCATGTTGAAGTGAGGCCAAGAAACAGGTAGAAATCATCATCCCTCATAGAGTTTGTACGTATGGTTAAAAGGTTACAGGGTAAGTGCACTTCGTTTTCAATCTGGCAGTTATAATGCTGTGTTCCTTTGAAGGAAATGAAATGGCAGGTGAGAATTTTCAGCATACACAGAGCTTCCTCACCACCTTCTCTCTCCCCTGTCGTTCTGCAG
Seq C2 exon
CACCCACCGCCCAGCCCAGGGACCCTGGCAGGGACTGCGTCGACCAGCCAGAGCTGGCCAACTGTGATTTGATCCTGCAGGCCCAGCTTTGTGGCAATGAGTATTACTCCAGCTTCTGCTGTGCCAGCTGTTCACGTTTCCAGCCTCACGCTCAGCCCATCTGGCAGTAGGGATGAAGGCTAGTTCCAGCCCCAGTCCAAAATAGTTCATAGGGCTAGGGAGAAAGGAAGATGGACTCTTGGCTTCCTCTCTCTGGCTGGCAAAGGGAGTTATCTTCTGGAATACATTAGCTCTTTCAAAAACCCACCCAGTGTTTAGCCTCAACGGCAGCCAGTTACCAGCTTCTCTCTGTAGCCTTCAGCAGTGTTTGCATCTCTGACATAACCACAGGCTGCTGTTTTCAAGAAGAGCAATCTGTTTGGATAAGAAAAACCTTTACTTTACAGCTTCCCTTTATAATTTGTTACACAGGAATAGTTAAATGCATTTGTTTGTTTGTTTTTTGAGACAGAGTTTCACTCTTGTTGCCCAGGCTGGAGGGCAATGGCGCGATCTCAGCTCACTGCAACCTCCGTCTCCTGGGTTCTTGATTCTCCTGTGTCAGCCTTCTGAGTAGCTAGGATTACAGATGCCTATCACCATGCCTGGGTAATTTTTGTATTTTTAGTTGAGATGGGGTTTCACCATGTTGGCCAGGCTGGTCTCGAACTTCTGACCTCAGATGATCTGCCCGCCTCAGCCTCCCAAAGTGCTGGGATTACAGGCATGAGCCACCACGCCCAGCCATCAATGCATTTTTTTTATTTTTTTTTTGAGACAGAGTTTCGCACTTCTTGCCCAGGCTGGAGTACAATGGTGCGATCTTGGCTCACTGCAACCTCCACCTCCTGGGTTCAAGCGCTTCTCCAGCCTCAGCCTCCTGAGTAGCTGGGATTACAGGTATGTGCCACCATGCCTGGCTAATTTTGTATTTTTAGTAGAGACGGGGTTTCTCCATGTTGGTCAGACTGGTCTTGAACTCCCGACCTCAGGTAATCCGCCCGCCTCGGCCTCCCAAAATGCTGGGATTAGAGGTGTGAGCCACTGTGCCCAGCCCATCAATGTGTTTTAAAGCTAGCTGTCAGGGTTCCACTTAATTTAAAGCTGGGCAGGGAGATGTGTAATGATTTCAAAGTTAACACCTGTTTGTTTTCTAAAGGGCATGCCAAGTCCTGCTGTATCAGGGAAGTATTCTGTGCTAAAATCAGCGATGGTTCATTGCTCTAGTCTCTCTCACCCTTCTAGGCAGTGCATCAGTCAGCTCTAAATCTGGTGCAGAGGGTTAACAGCATAACCCTTGTTGGCAAAATGGAATAGATGTTAAGACCTCAAATAGGGATTTGGGATGAAACAGCTGCAGTTAGCACTGTTATCTGAGCATGAAAGAACTGGAAACGCTCCTTACGTCGAGATGTTGGACCTTGAAGCCCTCCTGAGGCCAACATGCAAATCTGGCTGTGACGGTTCATCTGACACCTGTGTAAAGCTGACCAGCCTGCTCTGTACAGTGACAATGAGGAGCCCCTCTCTTCCTTAAGTAGGAATCTGTGAAGCAAAATGTTTGCTGCCAAAGACAAATCAGACTGTCAGTCATTAAAAACAGCATTAGCAGGATGAGGATAGCAATGGGGAAGGGTTGTGGGCAATGCAGTAACAGGGAAATGGCTTCAGAAATGGTTTGAGTTGGAAGACAACATTCTTCATCTCTCAGGACTTCTAATTCCTTGATGCTAAAAGAAGAGGCATGGATTCTATGAGCTTCCAAGTCCCTTTCCACTTTAACCTTCTACAAATCTTTCAGAGGACTGCCTAGTAGCAAAGGTTATTCCTGGACACAGGAAAGACGGGCATTACAGGGACCAAAGCTCTGAAAGGTGACTTTTATTACCAACACACTGGCTGGAAAAGGGACAAACCACATCACGGGTGAGTGATACTTCTCAGTCTTCTCTACTCATTCAACAAAGGAAATGTGGGCTGGGGCAGAGGTCTTTTTTCATTTAATACTGGAAAAATATTGAAGAGCATCCATGTTCACTTATGGCTGGTTTTGCTATAGAAATTGGAAAATAAAGGCCACTTTTTTGAAATCCCCAGTTTAATTAA
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000100767-PAPLN:NM_173462:25
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
Alternative protein isoforms
No structure available
Features
Disorder rate (Iupred):
C1=0.228 A=NA C2=0.321
Domain overlap (PFAM):
C1:
PF0767911=I-set=PD(59.8=91.2)
A:
NA
C2:
PF0767911=I-set=PD(14.0=30.4)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)