HsaINT0121854 @ hg19
Intron Retention
Gene
ENSG00000112541 | PDE10A
Description
phosphodiesterase 10A [Source:HGNC Symbol;Acc:8772]
Coordinates
chr6:165752767-165756991:-
Coord C1 exon
chr6:165756880-165756991
Coord A exon
chr6:165752848-165756879
Coord C2 exon
chr6:165752767-165752847
Length
4032 bp
Sequences
Splice sites
5' ss Seq
GAGGTATGT
5' ss Score
9.81
3' ss Seq
TTTCTCCCCATTCATCTTAGGGT
3' ss Score
9.78
Exon sequences
Seq C1 exon
AGACCGTGTAATTGGTTTGATGATGACTGCCTGTGACCTTTGTTCTGTGACAAAACTGTGGCCCGTTACAAAATTGACGGCAAATGATATATATGCAGAATTCTGGGCTGAG
Seq A exon
GTATGTCCTTGATTCTTATATTGACATAGATAGTGAGGAGAAATAAAACGTATGGATCAATTGCTAAGAATACTTTAGTTGTTCATGTTGATAGTTATTTCAGAGAACTGTGGTGAGTCACATACTGAAGGATTTAGCACTTATGCAGATACAAAGAGAGAATGATCATTCTTTTACATATTACTTACATGTGTGTCTAATTCTCTGAGCTCAACTGAAAGAGTTTAGGAACTTACTCACTGAACAGTAGTATAACAGTTATCTTACTTAACAGCTGATCTTTTGTTCATTCATTCAATAAACATTACTGGCCATCTACTTTAGATAGGCACTGGACAAAGTACTCAGAGGGTCCCATAATACAGGATATATCCACCTGCAGTTAAAAATTCAGGAGAATAATTGTTTTGCACCATAGACATTGAGAATATGTAAATATAACCAATAGCTCACCTGCAAATTATGTGTTCTGCAGAATGTGTGGAATATTCATTCATAATACTCCTGAAACAACACGTAAATGACTTTTATTAACGCCTTTTCTTGACTGACTTATCTAATTTATCAGTGATGTGCATTGTACTGCTCAATTTGCTGATGGAATTGTATGTAAGTAAGTAGAATATCATTCTCCCATCCAAATGAGTCACGGATACCTAGGCCTTTGCATATTCAAAAACTACTCTATGAAGAAAGCTGTAAATCTTTTGAGTACCTCTTCTGGTTTGAATAAATAAAAGTAAATTTGGAGGACAAAGCAGCTGATAATTCAATCGTATATCTCATTCATACAGAAGAATGTATGTAAAACATAAACAGCAAATCATTCAGCCACAAGTTTAGTGGGAAAGGTTTATCATGTTGAATTATTTCATAATAATAAAGCCAAAGTATGTTTACTGTATGAGGATCACAGACCTTGAGTTGATTATACTCCCGGCATGATTTCTCCAGAATGCTTTACACATCGCATATGCGTGGTCTCGCATGAGCTTTTTCTTTATTTTATTGTGTATGTGTCAGAACCTAGTTACCATCAGACTCAAGTAGGAAGATTGATTTCAATGCACAGTTGACCCTTGAACAACACGGGTTTGAACTGTGTGGATCCACTTATATGTAGATATTTTTCAATAAATATATTGAAAGATTTTTTTGGAGATCTATGACAAAAATACAGAACAACATATCCTAGAAATATAAAAAATTTAAGTATGCCATAAGTGCATAAAATATATGTAGATACTAGTCGATTTTATCATTTACTACCATAAAATATACAAAAATCTATGATAAGTTAAAATTTATCAAAACTTATATACACACTTATAGACTGGAGAGAAATGTAAACAAACAGATGCCGTGTTAAATTGTAACTGCGTAAAGTTAACCATAGTACATACGGCAGTACTGTAATAATTTTGCAGCAACCTTCTTTTGCTGTTACGGTGAGCTCAAGTGTTACAAGTATCCACTTAAAATGCTGTGTTTAAAATGCTCTGTGATGCTAATTGTCTCTGAGCTATTCGTCTCTCCAGTAAATTGTGTATCACAGTAAAAAGTGATCTCTCGTGGTTCTTGCATAGTTTTCATTGTGTTTAGTGCAATACCTAAGTCCTCCGTAACACCATAGCACCTATACAGAGTTACACTAGGATGCTGGAAGTGCTCCCAAGAAGCAGAGAAAAGTCATGACATGACAAGAAAAAGTTGAGTTGCTTGATACGTTCCCTAGACTGAAGTCTGCAGCTGTGGTTGCCGCCATGTTAACATAAATGAATCCCGTGTAAGGATCGTTGCAAAAAAAGAAAAGGAAATTCATGAAGCCATCACTGCAGCTATGACAACAGGAGCAAAAACCTTGCACTGTTTGTGAAATATCTTTTTATCTCATACTAAAAATGCACGTTTTGTTCAGGTACAGGATTGCTATGAGAAAGGCATAACTATAGACTGTAATATGATTTCTATATTCTAGACAAATGTAGAAAATGTGCAGTCATTAAATGACAACTTAAAGTAAAAGGAAGGTGCAGGATTAAAAGCTGGAGAATTTAATGCCAAAATGTGACCAATATGTAATGGAGATGTTTTTCCTTTATATTATTCACTGGTTATTCAGTCCACAGATAATGATTCAGCTCTCTGCATGCTCTTAGGTGCAGCCTTCACCAACCTCAATAGTCCACAGGAAGAAGCAGGAATATATTCACCAAGTCCTGACAGTTGTTCCCAGTATCTATAAAGTCCTGTCTCTTCTCTCCATCCTCACAATCTTTCCCCTCTTCAGGTCATCACCAACTCATGCCTTGAGTACTGCAACTTTCTAACTGAATTCCTTGCCATTACCTTTTAGAATTTGTGCAAAAGTAATTAATAATGTGGTCTTTGGTGCCAGGTTGCTTGAAATTAAAATTCCGCTTTGGCACTTGGTATTTAACCTCAGGCCAGTTTATGAGATAGGGATGATAATAATTCGGATTCCATCCGTACCCTGCTTCTGATCCTCTTGTTGTAATACAGACCAAAATCATGACCTCCGTGTGGAGAGCCCCACATGGCTGGCCCCCTGCCCACTGTCTGTGCAGGCATATTCCCCATCTCAGCCCCTAGCTGCCATTTAGGTCTTTGTTCCCTGCAGTCTCTGCCTGGAGCATGCTCCTGCCCTCTGTATTCTGTGAAAGCCTCAGATTGGCTCAGCCCTCTGTTAGAGCCATGGTCTGTAGCACTGGGTTCTTTTCCTTTTTAGCATTTTTGTTTCGAGTACATATTCAAATCATCGTTTGTTTAAAAAGCTGTTTCCTTGTTGGACTTGTCAAGTCTTTGAGAGCAAGGGACTTAGTATGTCTCACTCACTTTGGATAGAGAAGCAAAAGGTTTGAGACCACTGATTTTAAATTTAAAGTGGTAACAATGGAACAGCAGCCATGCTTGAAGTGGCTTTGCTTTGTCAGGACAAGTGCTTTGGTCCTGTACATAAAAATACCTAATTATGGTGATAGTAGTTTGTTTGTAGACCCTATTTTAGCAAGTCTGGGAAGTTTCTAGGCTGTACTTCTGATTTCTAAAAACATGACCAACGTTACTAAAATAATAAAAACTATGAGGGAAGAGTGGGAAGTTAGGAAAAATACTAGGAAATCTTAAGAAGATTGTACAAGTTTTACCTTTAACAAATAAATAAAAAGCAAGATAATTTCTAAAATCTTTAAAATGGGAACAGCATATCCTAGAATATTTCATAAGGATTAAATGAAATAATATTTACAAATTACTTAGCTCAGGGCCTGCATCATAGTGAATCTTTAGTAACTATTACCTGTAACTGTAAGTGAATCTTTAGTAACTAACATAGTGAATCTTTAGTAACTATTACCTGTAAGTGAATCTTTAGTAACTAACATAGTGAATCTTTAGTAACTATTACCTGTAAGTGAATCTTTAGTAACTAACATAGTGAATCTTTAGTAACTATTACCTGTAACTGTACGTGAACCTTCAGTAACTAACATAGTTAATCTTTAGTAAGTATTACCTATAATTGTAAATTAGATGATATGTGTAGTTTGTTGTACTGCGTCTTTACTAGCACATTTTAGTCGACTGGTGATGTTTATCTTCCTCTGTAAATATTCCTCTGGAAAGCCAAACTTCACTGAGTTCCATGCACTTGGAAGATCATTTGGAAGAGAGAAGGGCCTGGAGGTTATTCCATATCTTGTTATTGTTATTTCTCCTCACTGTTTACTGTATCTCCTCTTATTATAACATTTATTTACTAACTTCTGCAAAATGAAACCAGTAATAATGGCTGGGTTTCTGGTAATTCAGTAGTGGAGAAAATCAGGATAAAGTACAAAATAATGATACATTAAGTTTTTCTTTATTTTGATGTACTTTTCTTGGGTTAACAACCACAAACATTATTTGTTTTGAAGAAAATTAAGGAATAAAGGGAATAATTCAATAATATCAAAATAGTATAGCAATTTGAAATTTGAGAAAGCATGATTTTCTCCCCATTCATCTTAG
Seq C2 exon
GGTGATGAAATGAAGAAATTGGGAATACAGCCTATTCCTATGATGGACAGAGACAAGAAGGATGAAGTCCCCCAAGGCCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000112541-PDE10A:NM_001130690:19
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.333
Domain overlap (PFAM):
C1:
PF0023314=PDEase_I=FE(15.7=100)
A:
NA
C2:
PF0023314=PDEase_I=FE(11.0=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)