HsaINT0122169 @ hg38
Intron Retention
Gene
ENSG00000133256 | PDE6B
Description
phosphodiesterase 6B [Source:HGNC Symbol;Acc:HGNC:8786]
Coordinates
chr4:662509-663187:+
Coord C1 exon
chr4:662509-662618
Coord A exon
chr4:662619-663099
Coord C2 exon
chr4:663100-663187
Length
481 bp
Sequences
Splice sites
5' ss Seq
GAAGTAGGC
5' ss Score
3.93
3' ss Seq
CTCCACCACCTGTGTAACAGGTC
3' ss Score
6.56
Exon sequences
Seq C1 exon
ACCGGCAAACTGAAGAGCTACTACACGGACCTGGAGGCCTTCGCCATGGTGACAGCCGGCCTGTGCCATGACATCGACCACCGCGGCACCAACAACCTGTACCAGATGAA
Seq A exon
GTAGGCACCTCAGGGCGGGCATGTGAATTAGCCCTAAATCAACTCCACGCCCTTGGCGTGAATTAGGCTTCGCATAGCAGGCTATGTAGAAAGTGGAGTCCACGGCCAGGCCCCGTACTCCAGCACTGTGGGAGGCCAAGGCGAGGGGATTGCTTGAGCCCAGGAGTTCGAGACCAGCCTGGGCAACATGGCAAGAGCTCTCCTCTACAAAAACTTAAAAAAAAAAAAAAAAAAAAAAGCTGTGTATGGTGGCGCACACCTGTGGTCCCAGCTACTTAGGAGGCTGAGGTGGGAGGATCACTTGAGCCCAGGAGGTCAAGGCTGTATTGAGCCATGATTGCACCACTGCACTCCAGAGTGGGTGACAGAGGCAGACCCTGTCTCAAAAAAAAGAAAGTGGGGCCCATCTGGGGGGGCTGCAGAGCGCAGGGTGGGCCAAGGGCAGGTCCCACGGGCCTCACCTCCACCACCTGTGTAACAG
Seq C2 exon
GTCCCAGAACCCCTTGGCTAAGCTCCACGGCTCCTCGATTTTGGAGCGGCACCACCTGGAGTTTGGGAAGTTCCTGCTCTCGGAGGAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000133256:ENST00000255622:14
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0023314=PDEase_I=FE(14.5=100)
A:
NA
C2:
PF0023314=PDEase_I=FE(11.6=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
ACCGGCAAACTGAAGAGCTAC
R:
CTCCTCCGAGAGCAGGAACTT
Band lengths:
198-679
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development