HsaINT0122171 @ hg38
Intron Retention
Gene
ENSG00000133256 | PDE6B
Description
phosphodiesterase 6B [Source:HGNC Symbol;Acc:HGNC:8786]
Coordinates
chr4:663770-664221:+
Coord C1 exon
chr4:663770-663870
Coord A exon
chr4:663871-664113
Coord C2 exon
chr4:664114-664221
Length
243 bp
Sequences
Splice sites
5' ss Seq
CAAGTGCGC
5' ss Score
4.41
3' ss Seq
CCCTTGTTCCCTGGGTTCAGGAA
3' ss Score
8.87
Exon sequences
Seq C1 exon
ACCCTGAACATCTACCAGAACCTGAACCGGCGGCAGCACGAGCACGTGATCCACCTGATGGACATCGCCATCATCGCCACGGACCTGGCCCTGTACTTCAA
Seq A exon
GTGCGCGCCTTCCGGGAGGGGGCGCCTCGCGGGGCGGGCGGGTAGCCTGGGACCCCCGGCAGACACGGGGGCGCAGCGGCGGCACAGCCCGGGGGACGCAGCCCCGGATTCCGTCCCTGCCCGCCGGCCCCGCGCACCCCGGATGGGGCCTCGCTCGGGCTCCGCGCCTCCCTGCAGACGGGCGCTTGGGGCGGGGTCTCCACACTTGCTCCCACCTGCACCTCCCTTGTTCCCTGGGTTCAG
Seq C2 exon
GAAGAGAGCGATGTTTCAGAAGATCGTGGATGAGTCCAAGAACTACCAGGACAAGAAGAGCTGGGTGGAGTACCTGTCCCTGGAGACGACCCGGAAGGAGATCGTCAT
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000133256:ENST00000255622:16
Average complexity
IR
Mappability confidence:
NA
Protein Impact
Alternative protein isoforms
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0023314=PDEase_I=PU(22.9=97.1)
A:
NA
C2:
PF0023314=PDEase_I=FE(14.5=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
ACCCTGAACATCTACCAGAACCT
R:
ATGACGATCTCCTTCCGGGTC
Band lengths:
209-452
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development