HsaINT0124916 @ hg38
Intron Retention
Gene
ENSG00000011405 | PIK3C2A
Description
phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha [Source:HGNC Symbol;Acc:HGNC:8971]
Coordinates
chr11:17122702-17129467:-
Coord C1 exon
chr11:17129300-17129467
Coord A exon
chr11:17122814-17129299
Coord C2 exon
chr11:17122702-17122813
Length
6486 bp
Sequences
Splice sites
5' ss Seq
ACGGTAAGT
5' ss Score
11.81
3' ss Seq
TTATTTTTACATCCGTGAAGGTT
3' ss Score
5.75
Exon sequences
Seq C1 exon
AATCATTTTTCCTATCCAGATATCACAATTGCCATTAGAATCAGTTCTTCACCTTACTCTTTTTGGAATTTTAAATCAGAGCAGTGGAAGTTCCCCTGATTCTAATAAGCAGAGAAAGGGACCAGAAGCTTTGGGCAAAGTTTCTTTACCTCTTTTTGACTTTAAACG
Seq A exon
GTAAGTATTACCGAATTGTAATGGTGAGTCACTGTGGACACATCTGCACATCAGAATTGGCTAGATGACAAGGAGGTGAGGGGAGGAACATAGATGAGTGAATGAGCCTCTTCAGTTTTTCTAATGTGATAAAAGGAGGTCAGTTCAGAGACACAGATTAGAGGAAATCAAAGTTAGTCTGCTATATTCTAAACATATCTGAATAGGTATGCACAGCTTTGTTTGCCACTCACTGTTCCATGGAGAAAAGCAGCAGCCAATGACTGTCGTTTATATAAAGTACTACATTGTTGACATAATACCACAGTCTTGTAAGTTCCCTTGATGTTAACCAAAGAACTTCGTTTTTCCTTTTCCCATTTCTTTCCTACTCTTCTCCAGTTTTAGAGAATCTATAGGTGCACATTATTCCCTTCCTTAATTCTCTTTACTAATCTATCCCTTACTGCCAAATGCCCCTAGTCTTTAATTGCCATACATCCCACAAGTATGCAAAACCCTATTAGGGATTCTTTCCCTTATCCTTAGGGGTAAAGGAACTTCTTTTGAGCTTGGTGTCTGTTAATAGCCACTGGGATAGTATAATCTATATGGCCTTTCAGCTGAATATTTTAATTATGTTTTAAGGAATAATGTTTCATGAGATGATCAAGAGTTTTCCAAAGGAAAAATAATTGGGTAAGTTCGGGATATGTTACATTCAGCACATGGGTGCATTCTGGAGAATAGATGATGCACATTGGCATATTAAAGCATCTCTAGGCAGGGCTCTGTGGCTCATGCTTGTAACCCCAGCAATTTGGTAGTCCAAGGTAGGCAGATCACTTGAGGTCAGCAGTTTGAGAACAGCCTGGCCAACATGGTGAAATCCCACCTCTGCCAAAAATATAAACATTAGCTAGCTGGGCATAGAGGCACACCCCTGTAATCCCACCTACTCTGTAGGCTGAGGCATGAGAATCACTTGAACCTGGAGGCAGAGGTTTCAGTGAGCCCCTCCCCACCCCCCGCCAAAAAAAAAAAAAAGCATCTCTAAAGTTCTAAAAGAAAAATTAAAAAAAAAAAGGAGAAAAAAGCATCCCTAAAGCTTTGTAGTCAAGAAGCCTATTTAACTGGGTCTTATGGCAATATATTTACTATAATAACAAACACTTATGTAGCACTTACTATGTGCTAGGTATTCATCTGAGTGCTACATAGGTATCCTTATATTTCTCACAACTGCTCTATGAAATAAGTGGTGATTTTATCCCTTTTTACGGAGTGGGGGGAATCAAAGTACAGAGATTAAGTGACTTTCCCCAGGGCACTTAGCTAGTATGTGGTAGAATTGGGATTTGAACCAGGCAGTTTGGCTACAGGGTCTACATTCTGAACTATTACCCTATATTAACATACTGAAACTTAGTTGATACCATGACACTTTTTTGTTGTTCTAGAATATATCTTTTGAAACCTTGTGTCCCTTGGGACAGTTTGGGAAATGCTTTAATAATAGATCTATTTAACTTAAAACAAATACCGAGAATGAAAATTTCTGCTAATCTAATACTTTTTCTTCTTAAATGGCAAATACACCATTTGATTTGCCAGTAATCATCTGTTGACAATAATAGGATGTTCAAAACACTGACTTGACAAATTTGTTCTTGAAATATTCTTTTCCCATGTGCTTAAAAATAACATTTATTGGCTGGGCACAGTGGCTCACACCTGTAATCCCATCATTTTGGGAGGCTGAGGTGGGTGGATCACTTGAGGTCAGGAGTTCGAGACCAGTCTGGCCAACATGGTGAAACCCCATCTCTACTAAAAATACAAAAATTAGCCAGGTGTGGTGGCGCACATCTGTAATCCCAGCTACTTGGGATGCTGAGGCAAGAGAATTGCTTGAGGCTGGGAGGCAGAGGTTGCTGTGAGTCAAGACTGCGCCACTGGACTCCAGCCTGGGTGACAGAGCGAGACTCTGTCTCCAAAAGAAAAAAAAAACACATATTTATTTTAAAAATATTTTTCTTTATTTTAGTCGCTTCCCCCCTATTTGAGGAGGCAGTATAAGATTTTTTGTTCTCTACATTTTGGTGGATTCAGATTTTAATACCTGACATAATTTTGAACTACCAAAGGCTAAAGAAAGGCAGTTGAAGGGATTACTGTTAATGGTGTGTATTAGGAACCTTTTGCTAAATATAATACATTACTACTCTAAAACAGAATATGCTTATATACTGTGAAGAATTGTATTCACCACTGTCTTTGATAAATTAGTGTCAGAGAGCAGTTATATGAAAGTTAAATACAATTTCATCATTATCATTAATTTTTATAAATAAATTCTGAAAACCTTCTTGCTCTTGAAAGCACCAGGAGTCTTTGCATAATTAGAGAACTATCACATTTTGCCACTTTTATTGTCTAGTAATAAATGGTTTTGTTAGATAAATGATATAATATTCTTTCATAATTCAAGAGACTATCAAGTGAAGGGCAGTTGACTTCTGCTAGACATTTAAATAGTTTGCATCCAACACTCTGCTGTTAAAATAGTGAATAGATTGTATTAAGCTTGAGACTGCCAAGTAGTGCAGGCGATCTTGGTAATGTTAGGACTTCACGTTCAAGGAATACTCAGAAATTAAGAGGGAAGATGATTAAGAGAGATGATTATTATTATTACACTTTGTTTCTCTACATTAGTACATGTAGAGAAACAGTATATAATATAGTTGAGTTAACCACTGTGTTATAATGATTAGTAATCCTAGTCTTGAAATTCTTTATGAAATAATTTCTGTTGAAGATGCAATCTTATATGACCTAATGGTCACTATTATTGAAGCCAAATGACTCAAAGGCATTTCATTCAGCCTTAATAACAAATGAGTTCTTTTTTAAAAAACTTTTTTTTTGTAGAGATGGAGTCTCACTGTTGCCCAGGCTGGTCTCAAACTCCTGGCCTCAAGTGATCCATCTTCCCGCCATCCGATCCCATCCGGTAGCTCAGATTATAGGCGTGAGCTACCATGTCCAGCACAAATGAGTTCTTAACTAATTTTTCTGAAAACTGGCATATAAACAGAATTAAGCAGTTAACCTGTCTTTCCTTTACAGTTATTTCTGAGGGTTACTAAATAATTGAGGTGGCAAAGTTTTTTTTGTTTTTGTTTTTGTTTTTTGAGACAGAGTCTCACTCTGTCACTCAGGTTGGAGTGCAATGGCATGATCTTGGCTCACTGCAACCTCTGCCTCCTAGGTTCAAGTGATTCTCATGCCTCAGCCTCCAGAGTAGCTGAGATTACAGGTGTGTGCTACCATGCCTGGCTAATTTTTGTGTTTTGGGTAGAGACAGGGTTTTGCAATGTTGGCCAGGTTGGTCTCGAACTCCTGGCCTCGAGTGATCCACCTGCCTTAGCCTCCCAAGTGCTGGGATTACAGGTGTGAGCCACCATGCCTAGCAGTAATTGATATGACAAAGTTTTTTTTATAGAAAATCTTTAGCTAGCCCGTTATGGTGGCTCATGCCTGTAATCCCAGCACTTTGGGAAGCCAAGGCGGGAGTTTGAGACAACTCTGGCCAATATGGCGAAACCCTGTCTCTACTAAAAATACAAAAAAGTTATAGCCAGGTATGGTGGCTCGTGCCTATAGTCCCAGCTACTTGGGAGGCTGAGACGGGAGAATTGCTTGAACCCGGGAGGTGGAGTTTTGCAGTGAGGCGAAATTGCACCACTACACTCCAGCCTGGGCGACAGAACGAGACTCCATCTCAAAAAAAAACAGTGAAAATCTTTAGATAATAGATGCAGAAGGAATGATAGAATTAGAATATTATAATTTTGCAACCCATGCTGAAATAATAGATTTCGGCCAGGGTTTCTCAATCTTGGCAGTATTGACATTTCAGACCAAATAATTTTTTGTTGTGGAAGACTGTTCTGTGCATTGTAGGATGTTTAGCGGCATCCCTAGATTCTACCCATTAGATGCCAGTTGTCCCCCTCAGTTTACAACCAAAATTATTTCCAAATTACCAAATGTCTGCTGGAAGGAAAATCACTCCCAGTTGAGAACCATTGATGTAAGCAGTGATCATCAGTGCCGCCTTTTTTGTTTTTTGTTTTAAAACCTTAAAATCTGTGAAAATGCCTTCCTAAAACCATTAAATAGTTTTTCTGCAACTTCATAATTGATGGCTTAAACTGATGGCACTAGAACTAAACTGATCAATAGTAACATCACAGAGAGATAACCCAAAGAGTGTGTACCTTTTAATTTGATAGAATTAGAAGTAGTATACAATACCAACTGCAAAATAGTAAGTATTCTTGCCAAAGAACTAAATCTGAATCAAATCAGGCCTCTAGGTCTAACTTCTTCTCTATGGAAAATACAGGAGGACATGTGAAATGACACCAGAGGAGTATAACCAGCAAAATTCAGGATATGGAAAATTCTACAGAACAAAAGGCCTGGTATCATCAACAAATAAATAGAAAAAAAGAGAAGGAGACCAAACAAGAGTTAACAAACTTTTTCTGTAAAGGGTGCCAGATAAAAGTAGTTTAGGCTTTGCAGACCATATAGACTCTGTCACAAATGCAAAAGCAGTCGTAGACAGTACATTAACAAATGAGCATGGCTATGTCTGGTAAAAGTTTATTTACAAAGCCAGGTGTGAAGGCCAGTTTGTTTACATGTGGCTATAAATAAACTCTGTAAAGGCAGGTTGGAGTTTGCTGACCCTGAATTAAAAGATGCTTAAAAAGACATCCAAATGTATTGTGCCACTGCACTTCAGCCTGGGCGACAGAACAAGACTCCGTCTCAAAAAAAAAAAAAAAAGACATCCAAATGCAAGTGTTAGGCCTTGCTTGGATCTTGTTTTAAGCAAACCAACTGTTTTTAAAAAACATCATTTATGGGACAATCAGAGAAATTTGAATAGTGACTAGATATTTTATGGTCTTAAGTAATTATTGTTAATTATTTTAGGAGGGATAATGGTATTGTACTTATTACAGGAAACTTTATTTTTTAGAGATATATAACAGTATTTGTAGATGAAATAATATGATCAGGATTTGCCTTAAGTCTAGTTGGAAGTAAGGGTGGTTCTTAGACATAACAGACTATAGCCCGGTGTGGTGGCTCACACCTGTAATTCCAGCAGCTCAGGAGTTCAAGGCTTCAGTGAGCTATGATCACACCGCGCATTCCAACCAGGGCGACAGAGTGAGGCCCATCCCCATATATATATATATATGATGGATTATAAGGTATCAAAGATTCAAAGCCTGTTTGTCAAGAGAAAATTTTAAAACTGGAGTCTAGTTTTGGTAAAGATATTTGCTGTTTGAATAAAATGAACAAAGATTTGACAAACTATAGTTTTCTGCTTTTGTATATCTTACGTTGTTTTCAGAAATTTCTTCTGTGTAAAGATATGTCAATATCTTTGAAAGAATGTTTTGATTGAGTAGGCCATAAATTAGTAGTCTAGGGCAAGGGTCAGCATACTTGGCCCATTGCTTCTTTTTATAAATACAAATACAGTTTGTTAGAGCATAGCATGCATATACATTTATATGTTGTTCATGGCAAATTTGAACTACAACAGGAAAATTTAGTCTTGCAGCAGAGACTTTATGGTCCACAAAGCCTAAAATATTTACTCTCTGGCTCTTTATAGAAAAAGTTGGCAGACCCCTAGTCTAGGAAACAGATAAAACTTCTCATATCTGGCCAGGTGCGGTGGCTCATGCCTGTAATCCCGGCACTTTGGGAGGCTGAGACAGGCAGATCATATGAGCCTCAGGAGTTCAAGACGAGCTTGGGCAACATGGCGAAACCCCTTCTCTACAAAAAAAAAAAAAAAAAACAAGAATTAGCTGAGCATGGTGCCACGTGCCTATAGTCCTAGCTACTTGGGAGGCTGCAATGGAACAATCATCTGAGCCCAGGGAGGTCAAGGCTGCACTTAGCCATAGTTGTGCTACTACACTCCAGTCTGGGTGACAGCAAGACCCTGTCTCAAAACAAAACAAAACAAAAAAACGTGTTTTGTTTTCTTTGGCTTGTATTTTTGATCTAATGATTAAAGTCAGGAAGCAGTTCTGTAATCCAAACCACCACCTTGAGATATATTTCTTTGTAGAAAATCTTCAAAGACTATTCTTAAACTTCCTATTTCTAGAAGTTGTTTTCTGAGTCCTTACCTTTTTTGTGTTCTGTCCTCAACACCATTTTCCCCAAGATAATGTCCTTTAATTCTCCCTCTCTTTGTTCCCACCCTACATTTCAATACATTTACCCTACACCTGAAAAGTTTCAGTACAATGTGGAGAGTGAATCCTTCTGATATGTTCTTAAAGATATCCTTTTTATTTAGTTGATCTCATACTAACTTTTCAAATTCATTACATGTGTTGTAAATTTTGAATTGATTTTTAAAATGAAAATCACATTATTATTTTTACATCCGTGAAG
Seq C2 exon
GTTTTTAACATGTGGAACTAAACTTCTATATCTTTGGACTTCATCACATACAAATTCTGTTCCTGGAACAGTTACCAAAAAAGGATATGTCATGGAAAGAATAGTGCTACAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000011405:ENST00000265970:12
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.175 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0079219=PI3K_C2=FE(39.7=100)
A:
NA
C2:
PF0079219=PI3K_C2=FE(26.2=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development