MmuINT1026668 @ mm10
Intron Retention
Gene
ENSMUSG00000030660 | Pik3c2a
Description
phosphatidylinositol 3-kinase, C2 domain containing, alpha polypeptide [Source:MGI Symbol;Acc:MGI:1203729]
Coordinates
chr7:116368747-116372962:-
Coord C1 exon
chr7:116372795-116372962
Coord A exon
chr7:116368859-116372794
Coord C2 exon
chr7:116368747-116368858
Length
3936 bp
Sequences
Splice sites
5' ss Seq
ACGGTGAGT
5' ss Score
11.45
3' ss Seq
TTCTTTTTATGTTCATTAAGGTT
3' ss Score
8.06
Exon sequences
Seq C1 exon
AATCATTTTTCCTATCCAGATATCGCAGTTGCCATTAGAATCAGTTCTTCATCTTACTCTGTTTGGAGTTTTAAATCAGAGCAGTGGAAGTTCCCCTGATTCTAATAAACAGAGAAAGGGGCCAGAAGCTCTGGGCAAAGTTTCTTTAACTCTATTTGATTTTAAACG
Seq A exon
GTGAGTGTTAACTGAATTGTGATGGTGAGTTCTCTGATACTCTGTACATCAAAAACAGGCTGGAGGCCAGGTTGGAAGCAGTGACAGGCATAAGCTTTGAGCTAGAGAAAGTAGTCTCTCTGCTGTAGTCTCAGAGTTAGCTGGTGAATATGCAAAGGATGGCTTGTCACTCACTGATCCAGGAGAAAAGCGGTAGCCAAACACTGTCATTTCTGTAAAGTATATTATGACACAATGCAATGGCTGTATCAGTTCTTGATTCTAAAATCTATTTTTTATAATTCTCACCTTTCTCCATTTTCAGAGATAGAACAATATTAAACAGTTCTAACTCACTAACAAGTCCTTAGTGTTATGAGCCCTTGATCTAAGAGTTCTAAAGATCTTTCCTGGGGATAGTAACCTCATATGTGCATGTGGAGTTTCAAGTACAACCATGATTGCCATTCATTACCTTATATCTGAGGCACAGGGTCTCAGACTGACTAGCCAATGAGCTCCAGGAACCCACCACTATGTCCACTTCCCTCATCGCTGAGATTGCAAATATACCTGGCATCCTTGGCTTCTTAATATGAGCTCTGGAGATCAGGCTCGGATCATGCTTGTAGAGAAAGCATTTACCAACTGAACCGTCTCCTCGGCCCTGAAATTGTTTATTTTTTGGGAAATACAAAACAATTTATAGATGAAATATGTAATGAAGATTTGGAATTCTCCTCCAGAAATGGAGTCATAAGTGATTGTGTACTACCTAATATGGGTCGTAGGAACTAAGGTCATTTATAAGAGCAGCAAGTACTCTAAACCACTGAGCCATCTCTCTATCCTTTATTCATACATGCATACGCAAAAAATTTAAATATTAATCTTGGAAAAAAGAACTTTAATTTATCAAAGTATATAACTTAATTGTTTTAAATAGTTGCTAGTTCGAGAATAAGGATCAATGTATGTTTTGAGTCCCACTGCCCTTTTTTTTTTTAACATTCAGTTATAGTGTATGTGTGTGGGTGAGTCAGAAGGTAGTTTGCAGAAGTTAGTTCTTTTCTTCCACAGTGTAGGTTTGGAATTGATTACAAGAGCTAAGACATCTTACCAATCCCACTTCCTGTTTTTAATAAATATATTTTGTTATATCATACAACATACTCATTTATATATCATTCTTAAGTACTTTATATTACTATAGCCAAATGAAGACGTTGCAACAGAGACTGTTATAGCTGAGATTATAAATATGTGCTACCATGTCCAGCCTTTTAAACTGTATTTATTCATTTAAATTTACTTTATGTATGTGAACATTTTGCCTGCAAGGATGTCTGTATACCATGTACATACATGCATAGTAACCACAGAGATCAGAAGTCTGATTCCCTAGAATTAGAGTTACAGGCAGCTGTGAGCCACTGTGTGGATGCTGGGAATCAAACCTGGTTATTCTTCAAGAGTAACAAATGCTCTTAACCACTGAGGTAACTCTCTAGCCCCTAATTTTCATTTTTTATTGTTTTTAGGCACGAAATCACTATGTAGCCCACGTTATACCAAACTTAAGGTTCTGTCCCTTGAAAAAGAAAGACAGGGTTATGTTTGGTGGTGGACCCATAAGGTGTCGGGGAAGGGGGTGCCTTTGTTGGCCCACACTAAGGCATCCCTTCCCCCTGGGGTAGCAGCCACACTATGGCATAGTATAGAATAGAGTTTATTTAGGACAGGGGGAGGGGAGTTGAGGGGGTAGTAGAGACAGAGACAGACAGACAGACAGAGAGACAGAGAGAGAAAACGATTAGAGGCTGGCCTGGGCACGTGGAGAGAGGGGAGAGGGGGGAAGGGAGAAGAGACTGAGGGGAAAGGGGGTAAGAGAGCAAGAGAAGAGATGACACCACTTCCGCCACAGCTTGCCATTGCTCCCTTTCCACCTCTGTTCCATTATCACTTTATCTATTTGTGTGTGTGTGTGGTGAGAGCACAACTCAGAGCTCAGAGTACAGTTTTCTCTTTCAAACATGGGTTCAGGGAGTGGACCCAGGCTCTCAGGTTTCTCTGAAACTTCTCTGAATATTGAGATTACAAATATGTAGGCTCCTAAATATTTATTGTCTAGCCTTTTAGAGAAAAAAAAATGTACTGAGGAGTGCTAAATATAGTTTGCTTCAAGTAAGTTGTGTTTCAGTGGTACAAAGCACTTACTGATTCTCTTGGCTTTTTATTCTAATGGTAAAAATCAGGATGCAGTTCTGTAATCCAGGTCGTGACCTTGAAGTCCTGGTCTCTAGGGGAAACTTGGACACTTCCTGTTTACATAGTGGTATTAGACAACAGTGGCCGTCCTTATCCCTTCTCTGCTCTCTTCTCAATGCCATTCTTTCCAAGATGCATTTTTATTCTCCCTTTTTCTGTTCCCACCCCAACTTTAATATTTTATCTAACTTCTCAGTAGTGTAGTAGCTGACTCCTTCCAATGTATTCTTTAAAACTGTACTGTTTTACCAACATTCCAAGTTGATTATCATGTTTTGTGGGTTTGAAATTTTTTTTATTAATTTTTTTAATTAATTTATTTATTTATTTATTATATGTAAGTACACTGTAGCTGTCCTCAGAAGAGGGAGTCAGATCTCGTTACAGATGGTTGTGAGCCACCATGTGGTTGCTGGGATTTGAACTCCTGACCTTCGGAAGAGCAGTCGGGTACTCTTACCCACTGAGCCATCTCACCAGCCCTTTTATTAATTTTTTATTAGGTATTTTCCTCACTTACATTTCCAATGCTATCCCAAAAGTCCCCCATACCCTCCCCCCCCCACTCCCCTACCCACCCACTCCCACTTTTTGGCCCTGGCATTCTCCTGTACTGGGGCATATAAAGTTTGCAAGTCCAATGGGCCTCTCTTTCCAGCTAGGCCATCTTTTGATACATATGCAGCTAGAGTCAAGAGCTCCGGGGTACTGGTTAGTTCATAATGTTGTTCTACCTATGTTGGGTACTTTCTCCAGCTCCTACATTGGGGGCCCTGTGATCCATATAATAGCTGACTGTGAGCATCCACTTCTGTGCTTGCTAGGCCCAAGAATAGCCTCACAAGAGACAGCTATATCAGGGTCCTTTCAGCAAAATCTTGCTAGTGTATGCAATGGTGTCAGCGTTTAGAGGCTGATTATGGGATGGATCCCTGGGTATGGCAGTCTCTAGATGGTCCATCCTTTCGTCTCAGCTCCAAACTTTGTCTTTGTAACTCTTTCCATGGGTGTTTTGTTCCCAATTCTAAGAAGGGGCAAAGTGTCCACACTTTGGTCTTCGTTCTTCTTGAGTTTCATGTGTTTTGCAAATTGTAACTTATATCTTGGGTATTCTAAGTTTCTGGGCTAATATTCACTTATCAGTGAGTACATATCATTTGAGTTCTTTTGTGATTGGGTTACCTCACTCAGGATAATGCCCTCCAGGTCCAACCATTTGCCTAGGAATTTCATAAATTCATTCTTTTTAATAGCTGAGTAGTACTCCATTGTGTAAATGTACCACATTTTCTGTATCCATTCCTCTGTTGAGGGGCATCTGGGTTCTTTCCAGCTTCTGGCTATTATAAATAAGGCTGCTATGAACATAGTGGAGCATGTGTCCTTCTTACCGGTTGGGACATCTTCTGGATATATGCCCAGGAGAGGTATTGCGGGAACCTCCGGTAGTACCATGTCCAATTTTCTGAGAAACCTCCAGATTGATTTCCAGAGTGGTTGTACAAGCTTGCAATCCCACCAACAGTGGAGGAGTGTTCCTCTTTCTCCACATCCTCGCCAGCATCTGCTGTCACCTGAATTCTTGATCTTAGCCGTTCTGACTGGTGTGAGGTGGAATCTCAGGGTTGTTTTGATTTGCATTTCCCTGATGATTAAGGATGTCACAGTATTCTTTTTATGTTCATTAAG
Seq C2 exon
GTTTTTAACATGTGGAACTAAACTTCTCTACCTTTGGACTTCATCACATACAAATTCTATTCCTGGAGCAATCCCCAAAAAAAGCTATGTCATGGAAAGAATTGTGCTACAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000030660:ENSMUST00000170430:13
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.175 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0079219=PI3K_C2=FE(39.7=100)
A:
NA
C2:
PF0079219=PI3K_C2=FE(26.2=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Conservation
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Ribosome-engaged transcriptomes of neuronal types
- Neural differentiation time course
- Muscular differentiation time course
- Spermatogenesis cell types
- Reprogramming of fibroblasts to iPSCs
- Hematopoietic precursors and cell types