HsaINT0124939 @ hg19
Intron Retention
Gene
ENSG00000011405 | PIK3C2A
Description
phosphoinositide-3-kinase, class 2, alpha polypeptide [Source:HGNC Symbol;Acc:8971]
Coordinates
chr11:17167410-17169175:-
Coord C1 exon
chr11:17169064-17169175
Coord A exon
chr11:17167490-17169063
Coord C2 exon
chr11:17167410-17167489
Length
1574 bp
Sequences
Splice sites
5' ss Seq
ACAGTAAGT
5' ss Score
9.49
3' ss Seq
GTGTATATGTGTTTGTTTAGGCA
3' ss Score
7.68
Exon sequences
Seq C1 exon
TAATCATTGCCTTGGAAGTCATGAGCATATTCAAAACTGTCGAAAATGGGACACAGAAATTAGACTACAACTCTTGACCTTCAGTGCAATGTGTCAAAATCTGGCCCGAACA
Seq A exon
GTAAGTGTGTACCTCATAACTGAATTCCATTTGTTTGAATCTGAATAATTCTGCTAATTTGCCAATTTTCAACTTGTACATTTTTCATGATTTCATAGTTAGAATGGGGTGATGAACTCATCCTCAACAGGAATCTTCTTAGCAAATGAGGGGAGATGTTCAATCATGGAGGTTTAGGTAACATAGTCCTTAGAGGTAGAGGCATATTTGAAAATCAAAGTGGAGAAATTAAAATTTGGTTGGTAATAGCTTTATACAAGAGTGAAAACATCAGGGTGAGTCAGGGAAAAATGGGGAAGAAGGAAAAATTTTGAATACTAAATATGGGTTGGGGATGAAAAGAAAATCCACACTGACCTTTGTACCAAACTGAGAAAAATAAATTATTCATCACAAAATGAAAACTAATTCCCTGTTTTAAAAGTTCACTACTTTCAGTAGGTGGATGCTGTTTAAAAAAAAAAGTGCTTTCAATGCTTTCTTTTGAGGTTAAAGCAAAATAGAATGCAGCAAATTTAGCCATTTTGTTTTACTGCGTGAACCCTTGATGAACTTAAAATCGAATTTTTAATCTCTAAAGAGAATTATTCTTTATTTGTTAGAATTTTGGATGGAAAAATATCAGTGATGTCTGCTTTCTTTTTTTCTTGGTTTTCTTGAGTTTTGCTTTTATGTTAGGTAGAATTCATTTCAATTGGGTAAAGACTATTTCATAAAATTTGGTACATTTTAGCAGTCATTGGTAACTTTTCTTCTTAGTTTCTTAAGGAATGATGTTCTTTTTTTTTTTCTTTTGGAGACAGAGTTTCCCTCTGTCATCCAGGCTGGAGTGCAATGATGTGATCTTAGCTCACTGCAACCTCTGCCACCCACCCTCAAGCGATTCTCATGCCTCAGCCTCTGGAATAGCTGGAACTGCGGGCATGCACCAACCCACCCAGCTAATTTTTTTTTTTTTGTATTTTTAGTAGAGACGGGTTTTTGGTGTGTTGGCCAGGCTGGTCTCGAACTCCTGGCCTCAAATGATTCACCTACCTTGGTCTCCCAAAGTGCTGGGATTACAGGCGTGAGCCACCGCGCCCTGTCAGGAATGATGTTCTTGACTACATTTGCGTAATGTAGACTTAGGGTAGAAGAGCGAGTACCTTGTTCATGATGGGGAGTGGGAGGAAAATTGATTATCATTAGAAAAAATAATGCAGAAATTTAAATGACCTCCATCTGTTTTCTACCCCATATGCATTTGGCTATCAGCCATCTTTAGTGTTTTTAGCTCTCTATTCTCTATATATAGAACAGAAGTAGTTTTTGTTCCAAAAGCTATTTATATATCTGAAAGTAGGCTTGAAAGCATTTATGTTTTCCATTTAACAAACAAGTTTTTTTTCAGGATGTTGACTCACTTTTTTTCTGAGTCAGTTACAAATAATATTTAATTCTGATAGAATTTTATTTTCAGTTCTCAGAAAAACACTTTAGTTGCAAGATTTTATCATACACTTAACTATATTTAATTTGACAATAGAAAGACCAAAGAGTGGATGTGATTTTTTTGTGTATATGTGTTTGTTTAG
Seq C2 exon
GCAGAAGATGATGAAACACCCGTGGATTTAAACAAACACCTGTATCAAATAGAAAAACCTTGCAAAGAAGCCATGACGAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000011405-PIK3C2A:NM_002645:5
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.037
Domain overlap (PFAM):
C1:
PF0079413=PI3K_rbd=PD(27.9=76.3)
A:
NA
C2:
NO
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
ATCATTGCCTTGGAAGTCATGAGC
R:
CTCGTCATGGCTTCTTTGCAA
Band lengths:
190-1764
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)