HsaINT0124939 @ hg38
Intron Retention
Gene
ENSG00000011405 | PIK3C2A
Description
phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha [Source:HGNC Symbol;Acc:HGNC:8971]
Coordinates
chr11:17145863-17147628:-
Coord C1 exon
chr11:17147517-17147628
Coord A exon
chr11:17145943-17147516
Coord C2 exon
chr11:17145863-17145942
Length
1574 bp
Sequences
Splice sites
5' ss Seq
ACAGTAAGT
5' ss Score
9.49
3' ss Seq
GTGTATATGTGTTTGTTTAGGCA
3' ss Score
7.68
Exon sequences
Seq C1 exon
TAATCATTGCCTTGGAAGTCATGAGCATATTCAAAACTGTCGAAAATGGGACACAGAAATTAGACTACAACTCTTGACCTTCAGTGCAATGTGTCAAAATCTGGCCCGAACA
Seq A exon
GTAAGTGTGTACCTCATAACTGAATTCCATTTGTTTGAATCTGAATAATTCTGCTAATTTGCCAATTTTCAACTTGTACATTTTTCATGATTTCATAGTTAGAATGGGGTGATGAACTCATCCTCAACAGGAATCTTCTTAGCAAATGAGGGGAGATGTTCAATCATGGAGGTTTAGGTAACATAGTCCTTAGAGGTAGAGGCATATTTGAAAATCAAAGTGGAGAAATTAAAATTTGGTTGGTAATAGCTTTATACAAGAGTGAAAACATCAGGGTGAGTCAGGGAAAAATGGGGAAGAAGGAAAAATTTTGAATACTAAATATGGGTTGGGGATGAAAAGAAAATCCACACTGACCTTTGTACCAAACTGAGAAAAATAAATTATTCATCACAAAATGAAAACTAATTCCCTGTTTTAAAAGTTCACTACTTTCAGTAGGTGGATGCTGTTTAAAAAAAAAAGTGCTTTCAATGCTTTCTTTTGAGGTTAAAGCAAAATAGAATGCAGCAAATTTAGCCATTTTGTTTTACTGCGTGAACCCTTGATGAACTTAAAATCGAATTTTTAATCTCTAAAGAGAATTATTCTTTATTTGTTAGAATTTTGGATGGAAAAATATCAGTGATGTCTGCTTTCTTTTTTTCTTGGTTTTCTTGAGTTTTGCTTTTATGTTAGGTAGAATTCATTTCAATTGGGTAAAGACTATTTCATAAAATTTGGTACATTTTAGCAGTCATTGGTAACTTTTCTTCTTAGTTTCTTAAGGAATGATGTTCTTTTTTTTTTTCTTTTGGAGACAGAGTTTCCCTCTGTCATCCAGGCTGGAGTGCAATGATGTGATCTTAGCTCACTGCAACCTCTGCCACCCACCCTCAAGCGATTCTCATGCCTCAGCCTCTGGAATAGCTGGAACTGCGGGCATGCACCAACCCACCCAGCTAATTTTTTTTTTTTTGTATTTTTAGTAGAGACGGGTTTTTGGTGTGTTGGCCAGGCTGGTCTCGAACTCCTGGCCTCAAATGATTCACCTACCTTGGTCTCCCAAAGTGCTGGGATTACAGGCGTGAGCCACCGCGCCCTGTCAGGAATGATGTTCTTGACTACATTTGCGTAATGTAGACTTAGGGTAGAAGAGCGAGTACCTTGTTCATGATGGGGAGTGGGAGGAAAATTGATTATCATTAGAAAAAATAATGCAGAAATTTAAATGACCTCCATCTGTTTTCTACCCCATATGCATTTGGCTATCAGCCATCTTTAGTGTTTTTAGCTCTCTATTCTCTATATATAGAACAGAAGTAGTTTTTGTTCCAAAAGCTATTTATATATCTGAAAGTAGGCTTGAAAGCATTTATGTTTTCCATTTAACAAACAAGTTTTTTTTCAGGATGTTGACTCACTTTTTTTCTGAGTCAGTTACAAATAATATTTAATTCTGATAGAATTTTATTTTCAGTTCTCAGAAAAACACTTTAGTTGCAAGATTTTATCATACACTTAACTATATTTAATTTGACAATAGAAAGACCAAAGAGTGGATGTGATTTTTTTGTGTATATGTGTTTGTTTAG
Seq C2 exon
GCAGAAGATGATGAAACACCCGTGGATTTAAACAAACACCTGTATCAAATAGAAAAACCTTGCAAAGAAGCCATGACGAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000011405:ENST00000265970:5
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.037
Domain overlap (PFAM):
C1:
PF0079413=PI3K_rbd=PD(27.9=76.3)
A:
NA
C2:
NO
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
ATCATTGCCTTGGAAGTCATGAGC
R:
CTCGTCATGGCTTCTTTGCAA
Band lengths:
190-1764
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development