HsaINT0125320 @ hg38
Intron Retention
Gene
ENSG00000186088 | GSAP
Description
gamma-secretase activating protein [Source:HGNC Symbol;Acc:HGNC:28042]
Coordinates
chr7:77326212-77328637:-
Coord C1 exon
chr7:77328606-77328637
Coord A exon
chr7:77326274-77328605
Coord C2 exon
chr7:77326212-77326273
Length
2332 bp
Sequences
Splice sites
5' ss Seq
TGGGTAAGA
5' ss Score
8.91
3' ss Seq
ATTGCTCTGTTTCATTTCAGGGC
3' ss Score
10.93
Exon sequences
Seq C1 exon
GGTGATTTCTAACCTAGAAGCAAGAAATTTGG
Seq A exon
GTAAGAAAAGATCTGTAATAAAGCCTTCTGGGTTCCAGTCAGTGTTTTGTTTGTAGCACTGTTCTTCCTACCACTGTGGGTTGGCAAGAGAATCACTTCCAGTAGTGTGGTGCAGGCAGCACCTTTTAATATCTTGCTGTTAGAGTGGCCGCACGGCTCTTCCCATGTCTGTCTAGGCACCAGGACCTCCGGGGACAGCTGCTGAATGTGCTTTTGCGATGGGAGTCCCTGGGTGATGGCCTTGCGGTTCTCCTTATTTCCTGTCATACAGAGCTGCCCTCTGGCTGTGCCCACAGGATGCATTTTGGCATTTCCCTTGGCTTGGTGCTGCTTGCTTTCTAGCTGTCTGATCCTACCGGGTCTTGCCTTGTTTGTGCCTCTCATTTGGGTTAAAAATTGGGCACACAGGTCCTAGAGGCATAAAGATGAGGAGCTTCCAGGTAAGCAGTGTGGTTCTGGGGGAAAGAGCACAGGCTTGAGAGCTAGACAGAGCTGGACTTATATTCCAGCATGGCCTCTTGTGTGAACCATGTGCTCCTGGGCAAGTCACTTACCCATTTGTGCACTGTCCTTAGGGGAGTGAGGAGAAAATGAGACTAAATGGGGTAATGCAGATAGCACCTAACATAGTGCTTAGCACATGAGGGTACCTGAGGTGGCTGCTTTATTCCTTAGTGTGTAAAGAAGAAATGTTAACATGTGGCTTCTAAACCAAATGACAGGTATTATATAATCCATAGGTGCGGGGAGTGAGAGGATAGGTTAGGAGCGGGGATGGCTGGAGGAGGGAGGGAGGTTGGAAGAGGCTCCCCAGAGGGCTGACAGGTGAGTTAAGTCTTGATAAACAAAGGGGACTTGGCCAAGTGAAACCAGGGGAGGGGAATGCTGAGCATATTCAGGCACAGGCTTATTTGTAGTTGCCAGAAGAACACTTTCGTGCCTCATGAAGGTCAGCCTTCATTAAATAAGCTTTTGTTTTTATATCCCACTCCTGTTTTATGGGCTTGGATGTTGGGTGATTCTAATGGAAACTATTTTATACAGTGCATTGCTGCACCTCCTCCAGCTGTGCACACAGCACAGTGAACTGTGACAGTGCACTTGTCATCCAGCTTAGGCTGACAGAGCCTGGGCTCACTGACCAGCCCAGGAGGAACCAGCCTCTGCCTTACCAGGCCATCAATCCCTGAAGCCAGGGGATCTGCCCTGCCAGACACGGGCATGTGTGTGTGTGTTTCAGGCTTATCATCCTTGCATTGCTGGGGGTTTCGCAACACGGGGAACGTTGCTGGTCTGGCTGAGGTTTCTGTCGTGCCACCCCTCCTGCCCTGCTTATGGAGCTACTGTATGTGTCAGGGCCGTTTGCATCCTGTTACTAGTCAGTCTATCTTAATGCACTTTAGGAAACTCTTCCCTTTCCTTGCACGTGCTTTGCGTATACTAGTTCCCCATAAAGAATGTCACTGCCTGAAACAGAACATTCTGTGAAATGCAGGGCTGTTGGATTCACATGTTAAATTGTTTCATCTCAATCACGAGGGTTGTGTAGGATCCAGGGAAGATTTATCCCGGGGGGTCAAGAGATATCGATGCCCTCCCAGAAGGAGTTGCCAGCCCACTGAGCAGGGTGGTTCTGCCCTCTTGCCTGGCACTGGATCTCAAGTATTTAAGAAGAAAAGAATGGAATACAAAGAAGTTAGAAGCGCTTTGGGGCAGATTTTCCAGCAAGACTGGGTTTGTCTGCCCCTAGGGCCACTACACTGTAGTGTGCATTGCAAATCATGGTGGAGAAGGTACCATTTGATTTAACATATCACTTTTCCACCTTTACCTAACTACCTTTGTAGTCTGATAACTTGTGCCAGTTAGTATTATTTGCTGCAGTAATTGACTGGCCCCCTCAGCTCAGTAACTCCCAAGGCTACTGAACTACAGGGTTCAGAAAGTAGAAGGGAGCCATGCAGTCCTTCCACCGAGCGCTGTTCCCTCAATTTATGACCCCAGAAGGGTTAAGAGAAGGCCCAAGTCCCTCTGTTTCCAGTGGAGCAGAGGTTCTTAGCAGTGAGTTTTAGTGTTGAACAAAAATCAAAGCTAGAGCCTACTGGGGTTGAGGAATGTGTTGGTTTCTTTCTTTCTCGGTCATTCCCTGTTTCACACAGCTCTGATAAGTTCACCTTGTAGGACTAGGTCACACTTAGGTGATGAAAAATTTTCATCCTGTGTTATGTTTTCTCAATGACTCAGAGAAGGGAAACCCAGGCTGATTCTTCTTCCTTCTAACCCATCTCCTGAAAACTGCTCAGAGCCTAACTATTGCTCTGTTTCATTTCAG
Seq C2 exon
GGCCAAGATTAACACCCCTCCTGCAGGAGGAAGACAGCCACCAGCGGCTGCTCATGGGGCTG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000186088:ENST00000257626:22
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
NO
A:
NA
C2:
PF149591=GSAP-16=PU(4.0=19.0)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development