HsaINT0126158 @ hg19
Intron Retention
Gene
ENSG00000160447 | PKN3
Description
protein kinase N3 [Source:HGNC Symbol;Acc:17999]
Coordinates
chr9:131464802-131467822:+
Coord C1 exon
chr9:131464802-131465218
Coord A exon
chr9:131465219-131467581
Coord C2 exon
chr9:131467582-131467822
Length
2363 bp
Sequences
Splice sites
5' ss Seq
CAGGTGAAC
5' ss Score
5.56
3' ss Seq
GCTTTCCACCGGCTCTGCAGCCT
3' ss Score
5.06
Exon sequences
Seq C1 exon
GGCTCCCGCGGGCGCGCGGCGGGGAAGGCCAGAGGACCTGGGCGCGGGCGATGTGCCTCCTGAGCGTCCAAACCGGGGGTGAGGCGCGGTCACGCCCAGCGGGAACCGCAGGCGCCGAAGCCCGGGTACTGGGCCCAGAATCCCGCGGAATTTTGGATCCGAGGGAGGCGCTGGGGCGCGGGACCTCGGGCGTGGGGTCCCGGGCGCTGGATCGGCGCGGACGGGAGGCGGCGCTGGTCCCGCGGGCCAGCGGGTCTCGGGAGGGGGCGCCCGATCCCGCGTCTCCGGCGCCGCTTCCCGGGAAGTTTCAAGTTTGAAAGTCCTGGCGGAGGGTCTGCGGCTTCCGGGACCGGAGTGGCTGAGAGAAGGGCCCCAAGCGGCCGGAGCGGCGCCATGGAGGAGGGGGCGCCGCGGCAG
Seq A exon
GTGAACGGCGTGGGAGGGGCGCGCGGGCCCGGGGGGTGCGAGAAAGCCTCTGTCATCGCCCCGGAGCCCCGAACCGCGGCCGCTTCCCCCGATCCTCCCCTCACCCGCGCCCCTTCCCTGCCCCTGCCCTGGCCCCGGCCCCGCGACGCCCTCGCAGAGCAGACCTGATCTCCGGGTTCGGTGGTTCCTGGACCTTGCACAGTCTCCAAATCAGTCCGCGGCTGACCCGGAGACTGAACCCCAACCAGCCCGTGAGCGAGGACGGCTGAGTCCGCAGTGTGCGCCACCAGGGTGGTCCCCAGAGTGTCCTTAAGTCGGTTCTCCTCGGTGGGGCTCCAAGGCCGACGGGAATTAGCCGGGATAGAAAGGCGGGGCACAGGGGCCTGGGGGGGTTAGAATGTGCGCGCAGCGGGGGGCGCAGTCTGTGCGCGCTTGGCAGTGGCAGGAGTCCTTCCCGGAGCACAGGAGGCACGAGGGGAGCGTAGATGAGAGGGGAGCGGCCTCCCCCGCCCCAGGGCGGGAACCTTTGGGTACATAGCGGGTTCTAGAATGCGGAGGGGGCTGGGTTTCCTGCCAGAGCTGGCAGTAGGTGCGCGTGGGCCCGGAGGACCGAGGCCATGTCTATCTGCTCCTGAGGAGGGAGAGGTGGTGTCCTGTTCCGGAGCGAGTGGTTGGGAGGGGGGCATTTGCGGACAGGAGTGGGTCCCCGCAAAGAGCGGAAAGGAGGTGGTGTGTGTGTCCATGTTGGAGTTCCAACCCAGGGCAGACGGGACCATGGGGGTGTTGCGGGGTGCGTGTAGACTCCTTGAGCGCCCAAGCCAGTCGTTTAGGCCGCCTTCAGGGCTGGGGCTCGGTCTGCCCCCTCCCACCCCCTTCCTCTGGAGGTCCCTCCGCCTGTTCCAGACGTAGCTTGTACACATTTTCCGATTTCCTGCGGGGCTCCGCCCTGCAGCGGCAGCTGGGTGACTCAGGACCCCGGTGGCCGGGCCCCCAGCTCCATGGGACCTTTGTTTGCTCCGGTCTTTGGCTCTGGCCCTGTGGCCTAGGGCGGTCAGAGGATTTCCTGAGCCTCGCCCTTGCCCTCTGACAGCTGGGCCAGCAGGCCCCGCTGAGGTCTGGGGTGGGGGGGTCCCTGAGTCTGGGGTTGCGGCCCCTTCCACTGGGCTCAGGAGAAGATGGAACACAGAGAGGTAAGATGGGGTTCCTGCAACAGCCCGTGTTGCGGGGCATCATGGGTTACCCGGCCTGAGGTCACCTTTGGCACCGGTTGGTTTGAAATGCTGGCGGCTGGAAAGGAGGTGTTCCTGTTCCTGGCTCCAACCTGGGTGAAGCCGTGAGAGAGCCTTCTACTTCCTCCCGGGAGCTGAGCAGGGAGTGGGCACCCGGAGACCTCCCCAGTTCCTCTCTGTGCCTCTGCTTTGCTACCTGTGGCATTGGGACATCAGGGGAACAAGCCCTGGCTCCCAGGCCCCTGGCTGCCTTCTCATGTGGCTTCGTGTGAACCCCTATTCGGCGTAGCTTTTGTGGCTCCTGGACTCTACTTTGGGTCCCAGATGTAGAGAGAGCAGCCTGATTACCCAGGGCTGCCAGGGACAGCTGGGGCCCGAGAGATGGTGGCCCCTCCTCTGTGTCTTGACTGTGGGCAAGTTACTTCACCTCTCTGGGCCTCAGTTTCCTCACTAGAAAATAGGGGTAATAGTACAGGCGTGGTGGCTCACACCTGTAATCCCAGCACTTTGGGAGGCCAAGGCAGGTGGATCACCTGAGGTCAGGATTCAAGACCAGCCTGACGAACATGGAGAAACCCCGTCCCTACTAAAAATACAAAATTAGCCGGGCTTAGTGGCGTGTGCCTGTAATCCCAGCTACTCAGGAGGCTGGGGCAGGAGAATCGCTTGAACCCGGGAGGCAGAGGTTGTGGTGAACCGAGATCGTGCCATGGCACTCCAGCCTGGGCAACAAGAGCAAAACTGTCTCAAAAAAAAAAAAAAGAAAAAGAAAAAGAAAAAAGAAAATGGGGGTAATGACCACCGCTACCGGGTGGGGTGGCTGGGAGGAGTGATGTGGTAATATATGCAAAGCACTTAGAATAGAACCTGGCACCCATTTACCGTGTGAACTGTCCCCCCCGCCACATCCTTCTCTAACGGGCGGAGGACAGGAGCCTGGCCTAGATGAGTGGCCTCGGAGTTTCCATCTGGCTCAGGCCTGAGCTCTAAGGGGAGAGAGGCTTCCAAAACCCTGTGCGAGTCAGTCCTGGGTGCCGTCCCTTCCTTCGCCTCCATCTGCAGTGAGCAAAGGCTGCTGGTGGCCGCTGCACCCCATGGCTGTTCTCCACCCTCTGCTTTCCACCGGCTCTGCAG
Seq C2 exon
CCTGGGCCGAGCCAGTGGCCCCCAGAGGATGAGAAGGAGGTGATCCGCCGGGCCATCCAGAAAGAGCTGAAGATCAAGGAGGGGGTGGAGAACCTGCGGCGCGTGGCCACAGACCGCCGCCACTTGGGCCATGTGCAGCAGCTGCTGCGGTCCTCCAACCGCCGCCTGGAGCAGCTGCATGGCGAGCTGCGGGAGCTGCACGCCCGAATCCTGCTGCCCGGCCCTGGGCCTGGCCCAGCTG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000160447-PKN3:NM_013355:1
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion (1st CDS intron)
No structure available
Features
Disorder rate (Iupred):
C1=1.000 A=NA C2=0.753
Domain overlap (PFAM):
C1:
NO
A:
NA
C2:
PF0218511=HR1=WD(100=82.7)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)