HsaINT0126175 @ hg19
Intron Retention
Gene
ENSG00000160447 | PKN3
Description
protein kinase N3 [Source:HGNC Symbol;Acc:17999]
Coordinates
chr9:131469501-131475477:+
Coord C1 exon
chr9:131469501-131469684
Coord A exon
chr9:131469685-131475330
Coord C2 exon
chr9:131475331-131475477
Length
5646 bp
Sequences
Splice sites
5' ss Seq
CAGGTAGTC
5' ss Score
5.3
3' ss Seq
CCCGCTCACTCTCCCCACAGGGA
3' ss Score
13.81
Exon sequences
Seq C1 exon
GCCCAGGCCCAGCTACAGGAGTCCTCTCAGAAACTGGACCTCCTGCGCCTGGCCTTGGAGCAGCTGCTGGAGCAACTGCCTCCTGCCCACCCTTTGCGCAGCAGAGTGACCCGAGAGTTGCGGGCTGCGGTGCCTGGATACCCCCAGCCTTCAGGGACACCTGTGAAGCCCACCGCCCTAACAG
Seq A exon
GTAGTCAGAAGTTCCTCCCCCTTCAAAGCTCTCCTTCTTTTTGGGGGGAGGCCGGAAGCACAAACAACTCTGATGAAGAGTTCAAGAGTTCCAGTCCTGCCCCAGCACCCACTAGCAGCGTGACCTTGGCAAACTGACATTCCTTCTTCAAACCTCAGTTTATCCATCTGTAAAATGTGGATGATATAGCACCTACCTCATAGGGTTGCTGTGTTGCACGTGATGTGCTAAGCACAGTGCCTAGCACAGTCAGCACTCGGACAGCGTAGCTTGTATTTACATAAATAACCAGAATAATGCTTAAAGCACTGGTGTTAGGAAGCTCGCAGCCCTGGAAAGCTTGATACCCAGCACTGGGCAGCTTGGACTGTTAGAAAGTTTTCTAGGCTGGGCGTGGTGGCTCACGCTGGTAATTCCAGCACTTTGGGAGGCTGAGGTGGGTGGATCATGAGGTCAGGAGTTCCAAGACCAGCCTGGCCAAGATGGTGAAACCCTGTCTCTACTACAAATACAAAAATTAGCCGGGCGTGGTGGCGGGTGCCTGTAATCCTGGTTGCTCAGGAAGCTGAGGCAGAGAATTGATTGAACCCCGGAGGCGGAGGTTGCAGTGAGCCGAGATCACGCCACTGCACTCCACCCTGGGCGACGGGGCAAGACGCCGTCGCAAAAAAAAAAAAAAAAAAGGTTTTCTTGGGCCAGGCATGGTGGCTCATGCCTGTAATCCCAGCACTTTGGAAGACTGAGGTGGGCGGATCACCTGAGGTCAGGAGTTCAAGACCAGCCTGGCCAACATGGTGAAATCCTGTCTCTACTAAAAATACAAAAAAGTAGCTGGATGTGGTGGCACATGCCTGTAGTCCCAGCCACTCGGGAGGCTAAGGCAGGAGAATTGCTTGAACCCAGGAGGTGAGGTTGCAGTGAGCTGAGATTGCGCCGCTGCACTTCAGCCTAGGTAACAGGGCAAGACTCCATCTCAAAAAATAATAATAATAATTTCCTTGGAAAAAAAATAATAAAATTAAACTAAAATTGCTGGGTGCAGTGGCTCACACCTATAATCCTGGCACTTTGAGAGGCTGAGGTGGGAAGATTGCTTGAGCTCAGGAGTTTTTTTGAGACCCAGTCTCAAAAAAAAAAGAAAAAAAGAAAGTTTTCTTGGCTGGGCACAGTGGCTCAAGCCTGTAATTCCAGCACTTTGGGAGGCTGAGGTGGACGAATCATTTGAGCCCAGGATTTCTAGACGAGCCTGGGCAACATAGTGAAACCTCATCTTTAGAAACAAAAAAAATTAGCCGGGCGTGGTGGCGCATGCCTGTAATCCCATCTACTGGGGAGGCTGAGGCAAGAGAATTGCTTGAACCTGGGAGGCAGAGGTTGCAGTAAGCCAAGATTGCACTGTTGCACTCCAGCGTGGGTGACACAGCAAAACTCTTTCAAGAAAAAAAAAAAAAGAAAGAGTTTTCTGGTCTGGCTCAGTGGCTCATGTTTATAATCCTAGCAGTTTAGGAGGGTGAGGCATGTGGATCACTTGAGTCCAGGAGTTTGAAACCAGCCTGGGCAACATGACAAAGCTCCATCTCTACAAAAAATACAAAAATCGCCGGGCGCGGTGGCTCACGCCTGTAATCCCAGCACTTTGGGAGGCCGAGGCGGGCGGATCACGAGGTCAGGAGATCGAGACCATCCTGGCTAACACGGTGAAACCCTGTCTCCACTAAAAATACAAAAAATTAACCGGGCGTGGTGGCGGGCGCCTGTAGTCCCAGCTACTCGGGAGGCTGAGGCAGGAGAATGGCGGGAACCCCGGGGGGCGGAGCCTACAGTGAGCCGAGATCGCACCACTGCACTCCAGCCTGGGCCACAGCGAGACTCTGTCTCAAAAAAAAATAAAAAAATAAAAAAATTAGCCAGGTATGATGGTACGTACCTGTAGTCCCAGCTACTTGGGAGGCTGAGGTGGGAGGATTGCTTGAGCCCAGGGAGGTTGAGGGTACAATGAGCCATGATCGCGCCACTGCACTCCAGCCTGGGCAACAGAGAGCCCGTCTCAAAAAAAAAAAATTAGGCTGGGCACGGCAGCTCATGCCTGTAATCTCAGCACTTTGGGAGGCCGAGGTGGGTGGATCACCTGAGGTCGGGAGTTCGAGAGCAGCCTGACAAAAATGGAGAAACCCCGTCTCTACTAAAAAATACAAAATTAGCCGGGCCTGGTGGTGCATGCCTATAATCCCAGCTACTCAGGAGGCTAAAGCAGGAGAATTGCTTGAACCCGGGAGGTGGAGGTTGCAGTGAGCCAAGATGGCACCATTGGAATCCAGCCTGGGCAACAAGAGCAAAACTCTGTCTCAAAAAAAAAAAAAATTTGCAAAAATTAGCTGGGTGTGGTGGCGGGCGCCTGTAGTCCCAGCTACTCGGGAGGCTGAGGTGGGAGAATGGCATGAACCTGGGAGGCGGAGCTTGCAGTGAGCTGAGATTGTGCCACTGCACTCCAGCCTGGGTGACAGAGTGAGACTCCAAACAGAGTGAGACTCCGAGCAGAGTGAGACTCTGAGCTCTGTCACCCAGGCTGGAGTGCAGTGGCGCGATCTCGGCTCACTGCAAGCTCCTCTTCCCGGATTCATGCCATTCTCCTGTCTCAGCCTCCCGAGTAGCTGGGACTACAGGTGCCCGCCACCACACCTGGCTAATTTTTTGTTTTTGTATTTTTAGTAGAGACAAGGTTTCACCGTGTTAGCCAGGATGGTCTCGATCGCCTGACCTTGTGATCTGCCGGCCTAGGCCTCCCAAAGTGCTGGGACAGGTGTGAGCCACCGCGCCCGGCCAAAAAAGTTAATTTTCTTATCTTGCACTGAGATCTGTCTCCTTGTAGCAGCAGCCAAATCATCATCAACAAATAATCTGAGAGCATGGGCTTTGAAGCTGTATCCCACCGAGATACAGTGAGAGCTGGAAAGGCCAGTGCCTGTCTCCACAGAGCACTGCTACAGGGCCGACTGACCCCATTCCATTGTGAGCAGAGCTGAGAAGAGGAAATGCAGGCTCTGGATGGAGCCCTCTCACCTGGCCTTGGGGAATCGAGGAATATTTTCTTTTCTTTTTTTTTTGAGATGGAGTCTCGCACTGTCGCCCAGACTGGAGTGCAGTGGTGCGATATCAGCTCACTGCAACCTCCGCCTCCTGGGTTCAAGCAATTCTCCTGCCTCAGCTTCCCGAGTAGCTGGGATTACAGGCCTGCACCACCATGCCTGGCTAATTTTTGTATTATTAGTAGAGACAGAGTTTTGCCATGTTGGCCAGGCTGGTCTCAAACTCCTGACCTCAGGTGATCCATCTGCCTTGGCCTCCCAAAGTGCTGGGATTACAGGCGTGAGCCAACCATGCCCGGCCCAAGGAATGTTTTCTAGAGGAGGTGGTGTCTTGGCCTTGAAGGACTTACACGGGAGTACTTATGGCCAAGTAGACAAGTTGAGGAACGCAGAAGAAACAGCTTGTTAAAAGGCCTAGAAGTCAACTACTCAAGGCCACCCCATATCCTGTCCCCTGGCTAAACACCCCAGATACTTGAGTTGTCCTTTTTTTTTTTTGAGATGGAGTTTTGCTCTTATTGCCCAGGCTGGAGTGCAGTGACACGATCTTATTGCCCAGACTGGAGTGCAGTGGCGCAATCTTGGCTCACTGCAACCTCCGCCTCCCGGGTTCAAGCAATTCTCCTGCCTCAGCCTCTTGAATAGCTGGGATTACAGGCATGTACCACCACACCTGGCGAATTTTTATATTTTCAGTAGAGATGGGATTTCTCCATGTTGGTCAGGCTGGTCTCGAACTTCCGACCTCAGGTGATTTGCCCGCCTTGGCCTCCCAAAGTGCTGGGATTACAGGCGTGAGCCACCTCGCCCCACCTCTTTTTTTTTTTTTTTTGGAGACAGAGTCTTGCTCTGTCGCCCAGGCCGGATTGCAGTGGTGTGATTTCGGCTCACTGCAAGCTCTGCCTCCCGGGTTCACGCCATTCTTCTGCCTCAGCCTCTCGAGTAGCTGGGACTAACTACAGGCGCCCGCCACTGCGCCCGGCTAATTTTTTGTATTTTTAGTAGAGACGAGGTTTCACCATGGTCTTGATCTCCTGACCTCGTGATCTGCCCACCTCGGCCTCCCAAAGTGCTGGGATTACAGGTGTGAGCCACCACGCCCGGCCTTTTTTTTGGGGGGGGTGGGGGACAGAGTCTTGCTTTGTCGCCCAGGCTGGAGTGCAGTGGCATAATCTTGACTCACTGCAACCTCCGCCTCCCAGGTTCAAGCGATTCTCCTGCCTCAGCCTCCCAAGTAGTTGGGATTACAGGCGCCCACCGCCATGCCCGGCTAATATTTGTATTTTTAGTAGAGACAGAGTTTCACCATGTTGGCCAGGCTGGTCTCGAACTCCCGACCTCAGGTGATCCACCTGCCTCAGCCTACCAAAGTGCTGGGATTACAGGTGTGAGCCACCACGCCCGGCCTCAAGTTTTTGTTTTGTTTGTTTTTTTTTGAGCTGGAGTCTTGCTCTGTCGCCCAGGCTGGAGTGCAATGGCACAATATTGGCTCACTGCAACCTCTGCCTCCCGGGTTCAAGTGATTCTCCTGCCTCAGCCTTCCGAGTAGCTGGGATTACAGGTGCCCACCATCATGCCCGGCTGGTTTTTGTATTTTTAGTTGGGATGGGGTTTCGCCATGTTGGTCAGGCTGGGCTTGAACTCCTGACCTCAGGTGATCTGCCTGCCTTGGTCTCCCAAAGTGTTGGGATTACAGGCATGAGCCACTGCGCCCGGCCGAGCTGTTCTTTCTAAGCTTCTCTTTCTACCCTGGACCCCTGCCTTTGTTTACAAGTTCTCTCTGTGTGTAACCCCCAGGCCCAGACTCTCCCTAAATGATACTCTTGGGCCTGCTTCGTGTCCTCAAAAGCTGCTAGATCCCCACTGCTTTCTCTACCCTTTGAGGGACAACCCTCTAGTGACGTGACACATGAACTTACTCCGTTGACAAAACACGTTTCATATCCATTGGGAGAGGTGGGGCAGAGCTGGGACTCACCTCCACTGTTCAGATGGGGAAACTGAGGCCCAGGGAGCAGGTGGGTCCGGACAGGAAGCCAGGCTTCCTGCTCCCTGTCCCAAGCTCTTATCCTTGCCACAGTGCTCTCTAGGCCCCACTTCTAGGCAGCATCTCGTCATGTGCTGTGGCTCTGTGCAGCCTGGCTAAGGTCTGAGGTCTGAGCCTATGTCCCTGCCGCTCCAGCATGTGGAGGGGAGAGCCAGTTGCTCTGCCCTGGAAAGAGGTGGCTGCCACAGAGAAGTGTGCATTCTGGGACAACGTGGCTCCTCACCTGGGAGTGTCCAGGTCGGAGGCCTCCTAGGGTGTCATCGGGGTCCAAGGGTACCCTTTGGGGGGCTCATGGTGCTTGGGAGCTGCAGGACAGTCAGCAGGCTCCAGTCTAGGCACTCTAGGCCGCCACACTGAGTGAGGTTCCTCAGGTAACTGCCCTGGCCTCAGGTGGGTACGGTCTGGGTTCAGCCACCTCCTGGAGAGGGTGGCCTTCCTGGGGTCCCAGGACACCTTGGTGGTAGCAGTGGGAAGATGGCATCTGACAACGCCCCCCGCTCACTCTCCCCACAG
Seq C2 exon
GGACACTGCAGGTCCGCCTCCTGGGCTGTGAACAGTTGCTGACAGCCGTGCCTGGGCGCTCCCCAGCGGCCGCACTGGCCAGCAGCCCCTCCGAGGGCTGGCTTCGGACCAAGGCCAAGCACCAGCGTGGCCGAGGCGAGCTTGCCA
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000160447-PKN3:NM_013355:6
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.532 A=NA C2=0.130
Domain overlap (PFAM):
C1:
PF0218511=HR1=PD(43.8=51.6),PF154561=Uds1=PD(40.6=45.2),PF118963=DUF3416=PD(51.2=71.0)
A:
NA
C2:
NO
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)