HsaINT0133020 @ hg19
Intron Retention
Gene
ENSG00000206549 | PRSS50
Description
protease, serine, 50 [Source:HGNC Symbol;Acc:17910]
Coordinates
chr3:46754391-46755991:-
Coord C1 exon
chr3:46755708-46755991
Coord A exon
chr3:46754558-46755707
Coord C2 exon
chr3:46754391-46754557
Length
1150 bp
Sequences
Splice sites
5' ss Seq
ACGGTGAGT
5' ss Score
11.45
3' ss Seq
AATGGGGCCCTGTCCCACAGGCA
3' ss Score
8.21
Exon sequences
Seq C1 exon
GCGTGATGTTATCTACTCAGTGAGGGTGGGGAGTCCGTGGATTGACCAGATGACGCAGACCGCCTCCGATGTCCCGGTGCTCCAGGTCATCATGCATAGCAGGTACCGGGCCCAGCGGTTCTGGTCCTGGGTGGGCCAGGCCAACGACATCGGCCTCCTCAAGCTCAAGCAGGAACTCAAGTACAGCAATTACGTGCGGCCCATCTGCCTGCCTGGCACGGACTATGTGTTGAAGGACCATTCCCGCTGCACTGTGACGGGCTGGGGACTTTCCAAGGCTGACG
Seq A exon
GTGAGTCAAAGCCTCTGCAGACCAGGGCGGGTGCTGTGAGAAAGGACGTGGGTGCAGGCCAGGGTGCCACCACAGATGGATGTTTCTGAGGCACCTTCCCCAGGGAGCCTGCCGCTCCCGGGACCTTCCTGCCAGGCTCTCATCTCTGAGGTCTCCTTCCCCTTGAGGATCTCGTGGGGAACACCTCACTGCTGCTCCAGCCTCAGGGGACCCTGATTGCCTTTGAATCCTGAGTCAGGCCAGGGCATGTAAACAGAACTTCCTTGAAGGCAGAGAGGCACAGAGTAATACCTCACAGTCCACACCCACTGCCCAGGCATCGGCAGCTTGCAGCAGAGCACCTGAGGTCGGGGGAGCAGTCTTCTGTGTTGTAAAATGCTGCCCAGAAGGCCCACATGGCTGGCTAGGGGCCGTCTGCAGCTGGAGCTCATGGTTTCCCCTCCCCTCAGTGGGCCTCAACTCCTGGTCGTCCCAATTCAGGAGCAAGGCCCAGAGAGCAGGTGTGTTCTCTCAGGAACATCCAGGGGACCCTAGAACTGTCTACTTCCTTCAGGGGGTCCCCAGCCCATAAGAGAGATGCCCTTCCCTGTGGCCTCAAGGAACCAACTTACTCTCAAAACAGCTCAAGGGGGCTTCAGCCCATGTGGGAGGACCTGGGAGTGACTTTGTCATCCCTGCTGTGGCCTGTCTCCTGTCTCCCAGGAGCTTAGGCCAGGGACAGGGACACACTACTCAGGGAGGCAGAAGGAAGAAGCAGTGCCTGGCCTCCATGGAGGGGTCTGGGAAGGCTCAGCAGGGAAGAGGCCTGTGGGAGAAGGGATGCTTGAAGAGAAGGAAGGCTTGGCAGGCCCTCAGGAGGGAAGGAGTGGCAAAAGCCAAGAGGCCGAGTGTGGTGGAGGTGGTGTCAAGGGCCCCAGTGGCCTGGGCACTGCAGGAAGCGAGAGCAGGCCCGGCAAGGCTGGGTTGGGGGTACTCTGCTCCGGGGGCTCTGTGTTGAGGGCCCTAGATGGGTATGGGCTAGAACGAGGGCAGAGGTGTGTGGCTAAAGCAGAAAAGGTGGGACGTGGGGAACAGTGGAGAGAGGACGAGTGAGGCTGGCGGTAGTGGGCAGCGGTGAGTGGCTGCGCCTAAATGGGGCCCTGTCCCACAG
Seq C2 exon
GCATGTGGCCTCAGTTCCGGACCATTCAGGAGAAGGAAGTCATCATCCTGAACAACAAAGAGTGTGACAATTTCTACCACAACTTCACCAAAATCCCCACTCTGGTTCAGATCATCAAGTCCCAGATGATGTGTGCGGAGGACACCCACAGGGAGAAGTTCTGCTAT
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000206549-PRSS50:NM_013270:4
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0008921=Trypsin=FE(39.7=100)
A:
NA
C2:
PF0008921=Trypsin=FE(23.0=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Conservation
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GTGCTCCAGGTCATCATGCAT
R:
GTCCTCCGCACACATCATCTG
Band lengths:
351-1501
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)