MmuINT0127534 @ mm10
Intron Retention
Gene
ENSMUSG00000048752 | Prss50
Description
protease, serine 50 [Source:MGI Symbol;Acc:MGI:2447303]
Coordinates
chr9:110862262-110863896:+
Coord C1 exon
chr9:110862262-110862545
Coord A exon
chr9:110862546-110863729
Coord C2 exon
chr9:110863730-110863896
Length
1184 bp
Sequences
Splice sites
5' ss Seq
ACGGTGAGT
5' ss Score
11.45
3' ss Seq
ACTGGGGACCTGTCCCACAGGCA
3' ss Score
7.35
Exon sequences
Seq C1 exon
GAACCATGTTAACTACATAGTGAGGGCGGGGAGCCCGTGGATTAATCAGACGGCAGGAACCAGCTCAGATGTGCCGGTCCATCGAGTCATCATAAACCATGGCTACCAACCCAGACGGTACTGGTCATGGGTTGGCCGGGCCCATGACATCGGCCTTCTCAAGCTCAAGTGGGGGCTCAAGTACAGTAAATACGTGTGGCCCATCTGCCTGCCTGGCCTGGATTACGTGGTGGAGGACAGTTCTCTCTGCACTGTGACAGGCTGGGGATATCCCAGGGCTAACG
Seq A exon
GTGAGTCAGAGTCCCCAACCCCCATCCTAGGGTGCATGGGTGGGAGAGAGGACTTGGGTGTGGCTGGGGTGCCCCATGGACGAACATTTCTGGGGTGCCTTTTTTTAAGGAGCTGACCTATCCAAGAACTTTCTTTTTGGCGTCTCATCTCTCAAGTCTCCTGCCTCTTGGGGTGTCTTGTCAGTGAACATAAAACAGTCAGGCCTCTCAGAGTCACGACTGCTGACGTAAACAGAACTTTCTTTTTTCTTTAAAGATTTTTTAAAATTTTATTATTATATCTAAGTACACTGTATTTCAGACACACCCCAAAGAGGGCATCAGTTGTGAGCCACAGTGTGGTTGCTGGGATTTGAACTCAGGACCTTTGGAAGAGTAGTCAGTGAGTGGACCTTGTGAGACTCTCAGCTTTTCAGACACAAAAAACATCTTTTCTGGGAAGCATCTAGCAATCCCGAGAACCAGTCTCTTGTACTCTCTACCTACCGATACCCTATGGTTGTGTGCGGGTGACAAGCTCTCATTCTGAGACCTCCCTACTCTCAAGAAAGTTCTGTTTAGGGCTGGAGAAATGGCTCAGGGGTTAAGAGCTGAGAGTCTCACAAGGTCCACTCACATCCTCCTTCCCTCCAATGCCCTGCCCCGCATCCCTTGTCATTCCATTGTAGGAGCCAGGCTCTCATACCCGGCCACAGGATTGTTTTTCTGATGGGTTCTGGGACTATCCACTCCCTTTATGGAGTCAATGCACAAGAGACATGCCCTTCTCTGTATCCTTAGGGATCCGATTCCCCCCCTCCCCCCAAACAGCCATGCTGTGGCCTATCTGGGAATAATCGGAAGTTTCCTGACTCCCAGGAGTTCAGGCACCTTTTGGGTGGGATGGAAGATAGTGGTGATGTGGGGGTGAGATAGGGGATCCGGGTAGGGTTGTGGGGTCAGTCTGGGGAAGCTTAGTGAGAAAGAGGCCCCAGGGTTTTGGCCCTGAGAATCCTGGCAGGCGATTGGAAGAGGACTAGCAGAGCCAAGAGGCCAGTAGGTGTGGACTATGTTCCAGCACCTACTTGGGACCTGCTGGCCAGAGGGAAAATAGTCCAGATATATGGCCGCTATGCAAAGGAGACAGAGCCGGTGTCTGTGGGTCACAGTTAGTGGCTAATCCTGACTGGGGACCTGTCCCACAG
Seq C2 exon
GCATCTGGCCCCAGTTCCAGTCCCTCCAGGAGAAGGAAGTCTCTATCCTGAACAGCAAGAAATGTGATCATTTCTACCACAAGTTCTCCAGAATCTCCTCTCTGGTTCGGATCATCAACCCTCAGATGATCTGTGCCTCGGACAACAACAGGGAGGAGTTCTGCTAT
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000048752:ENSMUST00000051097:3
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0008921=Trypsin=FE(39.7=100)
A:
NA
C2:
PF0008921=Trypsin=FE(23.0=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
AACCATGGCTACCAACCCAGA
R:
AGCAGAACTCCTCCCTGTTGT
Band lengths:
355-1539
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Pre-implantation embryo development
- Ribosome-engaged transcriptomes of neuronal types
- Neural differentiation time course
- Muscular differentiation time course
- Spermatogenesis cell types
- Reprogramming of fibroblasts to iPSCs
- Hematopoietic precursors and cell types