HsaINT0133024 @ hg38
Intron Retention
Gene
ENSG00000151006 | PRSS53
Description
protease, serine 53 [Source:HGNC Symbol;Acc:HGNC:34407]
Coordinates
chr16:31087537-31087826:-
Coord C1 exon
chr16:31087806-31087826
Coord A exon
chr16:31087700-31087805
Coord C2 exon
chr16:31087537-31087699
Length
106 bp
Sequences
Splice sites
5' ss Seq
GTGGTAAGG
5' ss Score
8.37
3' ss Seq
TGACTAACTCCTTTCCACAGCCT
3' ss Score
8.1
Exon sequences
Seq C1 exon
GTCTTCAAGCCGCTCAGCGTG
Seq A exon
GTAAGGTCTGGGGACACGGGGCCTAGGTCTTACTTGGGTCTGGGTTGGGACTGGGGTGAGGTCAGGACAGGTATCTGCTGTCAGTGTGACTAACTCCTTTCCACAG
Seq C2 exon
CCTGTGGACAGCGTGGCCCCGGCCCCCCCAAGCCTCAGGAGGGCAACACAGTCCCTGGCGAGTGGCCCTGGCAGGCCAGTGTGAGGAGGCAAGGAGCCCACATCTGCAGCGGCTCCCTGGTGGCAGACACCTGGGTCCTCACTGCTGCCCACTGCTTTGAAAA
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000151006:ENST00000280606:2
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.125 A=NA C2=0.436
Domain overlap (PFAM):
C1:
NO
A:
NA
C2:
PF0008921=Trypsin=PU(18.3=76.4)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GTCTTCAAGCCGCTCAGC
R:
CAGTGGGCAGCAGTGAGGA
Band lengths:
175-281
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development