HsaINT0133029 @ hg19
Intron Retention
Gene
ENSG00000151006 | PRSS53
Description
protease, serine, 53 [Source:HGNC Symbol;Acc:34407]
Coordinates
chr16:31096101-31096581:-
Coord C1 exon
chr16:31096431-31096581
Coord A exon
chr16:31096346-31096430
Coord C2 exon
chr16:31096101-31096345
Length
85 bp
Sequences
Splice sites
5' ss Seq
TGGGTGAGT
5' ss Score
8.73
3' ss Seq
TCCACACTGCCTCTGCACAGGCG
3' ss Score
7.37
Exon sequences
Seq C1 exon
CCTGTGGATCCTTGAGGACAGCAGGTCCCCAGGCAGGAGCACCCTCCCCATGGCCCTGGGAGGCCAGGCTGATGCACCAGGGACAGCTGGCCTGTGGCGGAGCCCTGGTGTCAGAGGAGGCGGTGCTAACTGCTGCCCACTGCTTCATTGG
Seq A exon
GTGAGTCTTGGATCCCTCTCTGCTGTGCCCCCTGCCCCTGCCGGCAGCCCTGTCACCTGGTGCCGTCCACACTGCCTCTGCACAG
Seq C2 exon
GCGCCAGGCCCCAGAGGAATGGAGCGTAGGGCTGGGGACCAGACCGGAGGAGTGGGGCCTGAAGCAGCTCATCCTGCATGGAGCCTACACCCACCCTGAGGGGGGCTACGACATGGCCCTCCTGCTGCTGGCCCAGCCTGTGACACTGGGAGCCAGCCTGCGGCCCCTCTGCCTGCCCTATCCTGACCACCACCTGCCTGATGGGGAGCGTGGCTGGGTTCTGGGACGGGCCCGCCCAGGAGCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000151006-PRSS53:NM_001039503:7
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.137 A=NA C2=0.072
Domain overlap (PFAM):
C1:
PF0008921=Trypsin=PU(19.5=84.3)
A:
NA
C2:
PF0008921=Trypsin=FE(37.3=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CAGGCTGATGCACCAGGGA
R:
CATGCAGGATGAGCTGCTTCA
Band lengths:
167-252
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)