HsaINT0133039 @ hg19
Intron Retention
Gene
ENSG00000184647 | PRSS55
Description
protease, serine, 55 [Source:HGNC Symbol;Acc:30824]
Coordinates
chr8:10387017-10389055:+
Coord C1 exon
chr8:10387017-10387209
Coord A exon
chr8:10387210-10388804
Coord C2 exon
chr8:10388805-10389055
Length
1595 bp
Sequences
Splice sites
5' ss Seq
GTTGTAAGT
5' ss Score
8.3
3' ss Seq
CTCTGGTTCTCTGCCACCAGTCC
3' ss Score
7.06
Exon sequences
Seq C1 exon
AATGTGGTGACAGATCTATTTTCGAGGGAAGAACTCGGTATTCCAGAATCACAGGGGGGATGGAGGCGGAGGTGGGTGAGTTTCCGTGGCAGGTGAGTATTCAGGCAAGAAGTGAACCTTTCTGTGGCGGCTCCATCCTCAACAAGTGGTGGATTCTCACTGCGGCTCACTGCTTATATTCCGAGGAGCTGTT
Seq A exon
GTAAGTACCATGGGCCTCCCACTGCCACCTCTCAGGGCGCCCACCCCTGGGGCACCCTCCCCCTCACCCACACCTGGTGGCTGAGAGGAACCTGCGACTGCTCGGTATCCAGTCGGCATGAATGGCTCCCACCCATCCACCCACCCCCCAGCCTGTGGGGACGTGGAGGTAGCCAGCCTGAGGCTGTGTCCTCCTCACATCACCAGAGCCAGTGACTACAACCTCCCTGAGGTCACACCTACCCTCTCCCGGAACACCTGTGGCTTGATGGAGCCAAGCGGCTTGGTCCAAATGCCTCTCCTAGGGCATTCAAGTCCATCTAGGGGGAAATCCTTGTAATTCTGGAAGCCTGACTTCCTGGGCCACCTGACCCCCTACTCTCCTGCTCCTTGTAGAGCGTTCTCTGTGTGACAGCATGTGGATGGATGCCTGGCATTACCAAGGACTAACTATGTGCTGGGGACCCTGCTAAGAAACTTTCCCCTATTGGCCGGGTGCGGTGGCTCACGCCTGTCATCCCAGCACTTCGGGAGGCTGAGGCAGGTGGATCAGGAGTTCGGTGGTCAGGAGTTCGAGACTGGCCTGGCCAATATGGTGAAACCCCATCTATACTAAAAATACAAAAATTAGCTGGGCGCGGTGGCGTGCGCCTGTAGTCCCAGCTGTTCAGGAGGCTGAGACAGGAGAGTTGCTTGAACCCAGGAGGCAGATGTTGCAGTGAGCCAAGATCGCACCACTGGCACTCCCGCCTGGGCGACAGAGCGAAACTCCATCTCAAAAAAAGAAAAATAAACTTTCCTCTATTAACTCATTTAATCACACAGTGACCCCTGAAGCAGGTAGAATGAATAGCCCTCGTTTATAGATAAGGAAACTGATGTCCAATACACTGAGGCTGCTCACCCACAGTACCCATCTAGTATATAGAGACAGAATTCAAATTCTGGCTCTAGCACTTGTGCTTTCTGCCACACCAGCTCAAGGAAGTTTGAAGACACACACACTGATTTTAGAAGGTTAATCAAAAACCCGGGGACAGTTTCTTCATGGCATAACCACAGACCTTTGTGGCACCCGCTGTCGTGGGATATCAAATATCCTCTGGGGTTCGGAATGTGGGCTTATTACTGAAGATCCTGTCTGCTTGGTCAGTGGCAGGTCTAGACTAACTTCTGGTCCTGAGTTTCTAAAGTGCTGGTAGACCAGTTGATACAAAACAGATATAATAATGAATGCCTTATCTATCTGAAGGTCAGTTTGATCCGTGCCAAGTGGCTTTTTGTGGGCTGTGTAGAGTGCTCTAAACCCAGCTCGGCCTTTGCTGTATTAGACAGAAGCACCTCATTCATATCCCTGGGGCCCCTGATGGTGCAGTGGTCTGGCTGTGGTCTGCACACCAGCTATTCTGTTTTGTTTTGTTTTGTTTTGTTTTTTCCTACCTTTTTCCAATCCTCACACCTTCTGATCAACAGCCCCAGTAGGGTTTAAAGGTCCTAGAGCTACATGGGATTTAGGTTTCTGGGCACAGCCAATTCTGCCGCTTTTGAGACTTCCCTTCCCCTTCCACTTGCCCCTCTCTGGTTCTCTGCCACCAG
Seq C2 exon
TCCAGAAGAACTGAGTGTCGTGCTGGGGACCAACGACTTAACTAGCCCATCCATGGAAATAAAGGAGGTCGCCAGCATCATTCTTCACAAAGACTTTAAGAGAGCCAACATGGACAATGACATTGCCTTGCTGCTGCTGGCTTCGCCCATCAAGCTCGATGACCTGAAGGTGCCCATCTGCCTCCCCACGCAGCCCGGCCCTGCCACATGGCGCGAATGCTGGGTGGCAGGTTGGGGCCAGACCAATGCTG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000184647-PRSS55:NM_198464:2
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.040 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0008921=Trypsin=PU(21.1=73.8)
A:
NA
C2:
PF0008921=Trypsin=PD(63.4=97.7)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GTGGCAGGTGAGTATTCAGGC
R:
CAACCTGCCACCCAGCATTC
Band lengths:
342-1937
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)