HsaINT0133040 @ hg38
Intron Retention
Gene
ENSG00000184647 | PRSS55
Description
protease, serine 55 [Source:HGNC Symbol;Acc:HGNC:30824]
Coordinates
chr8:10531295-10533048:+
Coord C1 exon
chr8:10531295-10531545
Coord A exon
chr8:10531546-10532905
Coord C2 exon
chr8:10532906-10533048
Length
1360 bp
Sequences
Splice sites
5' ss Seq
CTGGTATGT
5' ss Score
8.14
3' ss Seq
GCGCTTTCTCTCTGGGCCAGCTG
3' ss Score
7.08
Exon sequences
Seq C1 exon
TCCAGAAGAACTGAGTGTCGTGCTGGGGACCAACGACTTAACTAGCCCATCCATGGAAATAAAGGAGGTCGCCAGCATCATTCTTCACAAAGACTTTAAGAGAGCCAACATGGACAATGACATTGCCTTGCTGCTGCTGGCTTCGCCCATCAAGCTCGATGACCTGAAGGTGCCCATCTGCCTCCCCACGCAGCCCGGCCCTGCCACATGGCGCGAATGCTGGGTGGCAGGTTGGGGCCAGACCAATGCTG
Seq A exon
GTATGTGACTGCTCAGCTTCCCCTGGGGAAAAAGCCACTGCAATGTGAAGGAGAGGGGAGGAAGCTAAGGAAGGAGTGAGGACAAGACTTGCATTGGAGCAGATTCCCGCTCAGTGGAGTCTCACAGTGCCCAAAGTTTAGCTCCTTTTGGGTGCCGAAACCCCAAGGTGAGACACCAGGTCTGAGCCAGTCCCCTAGTGCAGTCTGATCCAGCTAGCACAGAGCAGTGTGGTTTGTGTGTTTAACTGAATTTAAACTCTGCAGTTAGCCAGAGGCCCCTCTACTCTGTATTCATAAACATCTTCCCTGATTCCCACGGGTATGTTTCCTACCTGGCTCCTCCAGGCATTGGAGATTCCCACCCTGGGCTAGGCTCTGACGGTCCTGGAGCGTTGCCTGGCTCTTCTTAGAAATGAATCTGTTGTTCCTTGTTGTTATGCTGTTACTTGGCCAAAACAGAAGAAAGTCTACTGGGACAGAAAAATATGACGAAGGGCCCGCTGGACTGTCCCCCAAAAAAACCCAACAAAACCAAAAGCAAATAGATAGGGGAGGGGAGGGGATGAGAACAGCAAAGCATTGCGTCAGCCTGAAGGAGGCTCTCGATCCACAGGGATGATTTGCAGCGAGCCTGGGCCTGGACAACCGTGGGTGTTTCAGGAGTTTAGCAACCAGAGGGGGAAGCGGTGGGACCTTAGTTCTGGGCTCCAGGCACTCCTGGAAAGGTAGAAGAAGGAGAGGAGGCACATGGGCATGCACAAGTTTAAAAATCTTCAATCAGGGGAAGAAATGTGAAATCTCTTTGTGGTCAGAGTTAATGAGATGGAGAGGAATTCAGGTGAATTCCCGGCATCTGGCGGCCCAGAAAGGGCCTCTGCAAATCCCCTCTAATCCCATCTCAAAACACTCTGCCAACCTGCCCTTGCTGAGGACCTAAAGTTTTTTCACCGGGAGTGCAAACCCACTTTCCAAGGCCCTGTGTGAAGGAAATGCCATCCTCATGTAATAAAATGTCACAATAGGCAAATGTATTGATATGGCAGGATTATGCTGAGAAACAGTCAGTAGCCAGTTCCAAGAAGCTGAGTCTGTGGGGCTGACTGGGGTCAAGTTGGAAGTCTTCTTGGGAGTAGAAATTTGGTTTTGAATGAGAAGAATAGTTCCAGTAGCTGTGGGAGTTGTTGGGGGAGTGGGTAAGTTGCAGGCATGGGGTAACCTGAAGGAAGTGAGGGGCTGCAGAGCCTGTGAAGGAAGGGGATGGGGGCTGGGGGACACAGGGCCGAGGGCACAGTCAGCTGCATCACGAACGTGGGGACATGAGGCCCAGTGGCTTCTCTAATGCGCTTTCTCTCTGGGCCAG
Seq C2 exon
CTGACAAAAACTCTGTGAAAACGGATCTGATGAAAGCGCCAATGGTCATCATGGACTGGGAGGAGTGTTCAAAGATGTTTCCAAAACTTACCAAAAATATGCTGTGTGCCGGATACAAGAATGAGAGCTATGATGCCTGCAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000184647:ENST00000328655:3
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0008921=Trypsin=PD(63.4=97.7)
A:
NA
C2:
PF0008921=Trypsin=FE(20.6=100)
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GGACCAACGACTTAACTAGCCC
R:
TTCTTGTATCCGGCACACAGC
Band lengths:
346-1706
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development