HsaINT0133050 @ hg38
Intron Retention
Gene
ENSG00000185198 | PRSS57
Description
protease, serine 57 [Source:HGNC Symbol;Acc:HGNC:31397]
Coordinates
chr19:685546-687188:-
Coord C1 exon
chr19:686925-687188
Coord A exon
chr19:685923-686924
Coord C2 exon
chr19:685546-685922
Length
1002 bp
Sequences
Splice sites
5' ss Seq
TCGGTAAGA
5' ss Score
10.53
3' ss Seq
CACCTCTCCTTTCACTCCAGGCC
3' ss Score
9.26
Exon sequences
Seq C1 exon
CTGAACGGCTCTGCTGTCCTGGGCCCTGCAGTGGGGCTGCTGAGGCCGCCAGGGAGAAGGGCCAGGCCCCCCACAGCGGGGACACGGTGCCGGGTGGCTGGCTGGGGCTTCGTGTCTGACTTTGAGGAGCTGCCGCCTGGACTGATGGAGGCCAAGGTCCGAGTGCTGGACCCGGACGTCTGCAACAGCTCCTGGAAGGGCCACCTGACACTTACCATGCTCTGCACCCGCAGTGGGGACAGCCACAGACGGGGCTTCTGCTCG
Seq A exon
GTAAGATCCCCTCCCTGCTCCACCCACTTACTGTGTGGGGAAACCAAGGCCCACAGAGAGGGTCAGGGCCAGGAAGGGCCTTGGGAACTGAGTCCCATTGATGTTGGACCAGACGGAGAAGCTGAGGCCCAGGGAAGGCAGGGAGTTGGCAAGGGTCATGCAGGGCTGCCATGTTCAGCTGTGCAGGTTGCGCACTGCACAAAGAGCCAAGCACTTGTGTATTTATACAAGCAGTATTCAGTAGAGGGTAGTAACAGATTGAGAGGAAGCAGCTCCCACTCCTAAAACCTTGCCAGATAAACGAATCCCCAGGTGCCAAGGGAGACACTGGCCCTGGAGGGTCTTTTACCGCAGGCAAGAGAGCGACTTGGTTCAGGACACACACTTAGCCCAGCAGCCCGAGTCCAGGAGAAATGAGACTGTCCACTTTCCCGATGCGTGACCTTGGAAAAGTCACTTGATTTCTCTGGGCCTCTTTTTCTCCATCTGTAAAACTGCTACACTATTAGTATCCAGTTGATGGTATCAGAGCGGATTCTAGATGGCAGGAGGGTAGGATGAGGGATTTTAGGGTGAGTATACGGGGAGCCCTCTCCAAGGAGAGCACCTTTGAGCTGAGACTTGAAGGAATCCTTAGAAGATCTGAGGAAACACACGCAAGGCAGAGAGACCTGTTAGTAGAGGGCTGCCGCGTACAGCTGTGTAGGTTGTGCACTGCCCAAAACACTGCAGACTCGAATGTTCACACAGGCAGCATCCAGCGCAGGGCAGGAACAGGTCTCCAGGCTATACAAAGGCCGTGGAGCACTGAGGAGGCTCAGCGGGGAGGGCAGAGAAGTGGGTGGGGGCTGGGTCCTCAGGGCCTGGAGGGGAGAAATGAATTTACTTTTTCCTTGGAGAGCAGTAGGGAGCCACAGAGGGTTCTGAGGCAGGGAGGGCCGTGGTGAGATGTGCCTGCAGCAGCTCCCAGAGGCCCTGACCTCACCTCTCCTTTCACTCCAG
Seq C2 exon
GCCGACTCCGGAGGGCCCCTGGTGTGCAGGAACCGGGCTCACGGCCTCGTTTCCTTCTCGGGCCTCTGGTGCGGCGACCCCAAGACCCCCGACGTGTACACGCAGGTGTCCGCCTTTGTGGCCTGGATCTGGGACGTGGTTCGGCGGAGCAGTCCCCAGCCCGGCCCCCTGCCTGGGACCACCAGGCCCCCAGGAGAAGCCGCCTGAGCCACAACCTTGCGGCATGCAAATGAGATGGCCGCTCCAGGCCTGGAATGTTCCGTGGCTGGGCCCCACGGGAAGCCTGATGTTCAGGGTTGGGGTGGGACGGGCAGCGGTGGGGCACACCCATTCCACATGCAAAGGGCAGAAGCAAACCCAGTAAAATGTTAACTGAC
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000185198:ENST00000613411:4
Average complexity
IR
Mappability confidence:
NA
Protein Impact
Alternative protein isoforms
No structure available
Features
Disorder rate (Iupred):
C1=0.091 A=NA C2=0.235
Domain overlap (PFAM):
C1:
PF0008921=Trypsin=FE(38.7=100)
A:
NA
C2:
PF0008921=Trypsin=PD(18.7=60.9)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CACTTACCATGCTCTGCACCC
R:
CTGAACATCAGGCTTCCCGTG
Band lengths:
350-1352
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development