HsaINT0137041 @ hg19
Intron Retention
Gene
ENSG00000116191 | RALGPS2
Description
Ral GEF with PH domain and SH3 binding motif 2 [Source:HGNC Symbol;Acc:30279]
Coordinates
chr1:178858777-178861442:+
Coord C1 exon
chr1:178858777-178858831
Coord A exon
chr1:178858832-178861364
Coord C2 exon
chr1:178861365-178861442
Length
2533 bp
Sequences
Splice sites
5' ss Seq
AAGGTAAGA
5' ss Score
10.57
3' ss Seq
TTTATAATGGAATCCAACAGGAA
3' ss Score
4.24
Exon sequences
Seq C1 exon
GTAGCAGCGATGGTTCTGAACTAAGTGAAGAGACCTCATGGCCTGCTTTTGAAAG
Seq A exon
GTAAGATAAATTGTCCATTTGAACTACTTGGAGTTTATTTTGTCTGGGTTAAATAATATAATACAAATTTTCAGAGATAATATTTACTACATATCCCTAAGCGATTAAGTTTTCTACTGGTAAAAGAAATTAGAAGTTGATATTTAAGTTTGGATATGTAAGTAATGAGAATGAATGATAGTCTTATCTCTAAATGTTTATTTGGTGGCATGACACATGTATTTGAATTTTAATACATTTACATTTATAACTTAAAAATAATAACCGATCATCGACAAGTAACCTACTTACATATTCAAAAAATTATTTCCTTAAGTTCTGGTTCATTTAAGTAATTTTAAGGCATTTAGTGGAATGGTCAACTTTATTCTCTGCTGCTTTGTCAAGGACAAAATGATTTAATAAATTTTAAATTATACAAGTAAAGCAAGTTAAGGTTAGAATTTAAATGGTCATAAACTCAAAATTTTCAGAGTACACTTTTATACTGAAATACTCTAAGTTGTGCTCCCTTCTCCTTCCTTTGTTGCTTTAAGCTGTTAAATCTGTCATCTGCCTGTAGCAAATATCATACTATATTGAGGTCTAAGTACATATAAGATCTGAAGAATGTGACCAAACAATGCAAATAATTATTTATTAAATGTCCATTAGGATTCTTATGTTTTCACTGACCATTTCAGTTCTGCCATTTCAGACTCATAAGGTATTTGGCTTTTGACCAAAACAATTGCTCCCTTTTTTGTATATGAACTAAGTAACTAAATTTCTGAAAATGCCTATATTCATTACTCAAGCGGGTCATTTAGATTGAATGTTAAATGTCATATTAATACTGAAGTTGAAAATGTGTAATTGCATAACTCCTTATCAGTCACAATTTATAAAACAATTTTAAATTAAATTTTATTTGAAATCATAAATTTCATGCTGTTTAATTGGAAAAATAGATCCTTATTTTTTATGTGACTTCATAAAGATTTCTCACTATTATGTGATTAAGATTTTGTTTATAAGTTCTACATTGCAAAGTACTTTTGATCCTTTCTACTCTAATTATCAGTGTTCCCAACTTTTGTTCTCTTTGTTTTGCGGGATAATAATAAGTAAAAACAAATTATTTTTATTTATTTTTGCATTATTTTTCTTGCAACCTTTACTTCTGATCTGTTCATTTGGGTTTGCCTGAAATGTGAAAAACACAAGAATTGCCTTTGACATGTTGTCTGAATTTGTTCAAATTGTCTTTCCCTCTAGAAAGAACGTAAAACCATGAGAAGTTGATTATAGAGTGTACTGTAATCTTTATATTTAAAAAATATTGATTAACCAAATTGTTTTTTAGATTGCTTGACTTATGACTAACCAGAATGGTGGTGTGTTAAATAATCTGTTCTCATCCCAGCAGGTTACTTATGAAGACAGTATTTAATGATGTTACCTTCACGTCTCAAAACAATTTTTTTGCTTTATAACAGGTGTTTTGCTTTGCAGACATGTGTGGCTAAAAAAAGCTACTTTTCTTATGCCAAGTTTAAAATAGTGGGCTCTTAGAACATTTTGAGAACAGTGAAATGAATGCTGCCCAGCAAGATTCAGACATGAAATAATAGAAAGTGAATAAAGAACTAGGATATAAAGTACTACTCATGGATAGTGAACTTGAAAAATGTACTCTGAATGTTGACATACCATTTTCTGTTCTTATTTTCTAGACAGACATCAAATACATTGTCTTATTTTCTAGACAGAAATCAAATACATTGTTGTCTTTTTTTCTAGACAGACATCAAATACATTGTTTAAGTTGCTAAAATAATGCTTTTCCTTTAAAACATCATTTATCAACAGTGCTTTCGGGTTTTCCTAGGCAAAGAAGTATCAGTATTTTTATGTGTCTGTTTTTATTTTTTTTGTTTTTAACTATTATGTGCCATTTTGGATAAGTATTAACTCATCATTTTTATCATTTATTGGCTTTGTCAGTTAATGTAGAAATAATATAACGCCTATATTACTCAGTTCATTTCTTTTATTTACTATAAAGGATAAAGAGGAAAATAAAGTTTTCCTCATGAGTTTACAAGCCACATTGCTTTTAGGTGTCTTCATAGGGACATATAATAAAAATGAATTACTTATATAAATCCGGGCATCATATTTAAACTAGAATCCAAGAAGTGGTATAGAAACGTAAGAATTTTTGAAGTATTTTTGAGGTTTTTTTTTTATTATTTGGCTATAAATAGCTCTTTAATTCTTTTAGCAGATTTGTGAAAGTGAATGTATATGTAAATATATGGTGTGTACTAAATACCTCTAAGTATTTCTAGAGTCAATAGTAGAAGAAAAAATTTTTTGAAATCTATGCTGCATGCTTTAAAAAAGAAAGAGGAACAATCACATACTATCCTTTTGTAAGATTTAGAAAGCTATATTACAAGAAGAAACTATTATACTGTTCTAGGTATTGATAATGACTGTGTGAATAAAAGTATATGTAATATATACAATTTATAATGGAATCCAACAG
Seq C2 exon
GAACAGATTATACCATTCTCTCGGCCCGGTGACAAGAGTGGCACGAAATGGCTATCGAAGTCACATGAAGGCCAGCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000116191-RALGPS2:NM_152663:14
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.484 A=NA C2=0.222
Domain overlap (PFAM):
C1:
NO
A:
NA
C2:
NO
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)