HsaINT0137042 @ hg19
Intron Retention
Gene
ENSG00000116191 | RALGPS2
Description
Ral GEF with PH domain and SH3 binding motif 2 [Source:HGNC Symbol;Acc:30279]
Coordinates
chr1:178861365-178863159:+
Coord C1 exon
chr1:178861365-178861442
Coord A exon
chr1:178861443-178863053
Coord C2 exon
chr1:178863054-178863159
Length
1611 bp
Sequences
Splice sites
5' ss Seq
CAGGTACAA
5' ss Score
7.09
3' ss Seq
TCTTTTCTTCGTTATTATAGTTC
3' ss Score
7.22
Exon sequences
Seq C1 exon
GAACAGATTATACCATTCTCTCGGCCCGGTGACAAGAGTGGCACGAAATGGCTATCGAAGTCACATGAAGGCCAGCAG
Seq A exon
GTACAATTCCCCTGCATTCAGGGGTCACAGAACTCCCTTATGGTGTTGGTGATTGGCTTACATGGGTGTGGTCTGACGTTATTTCTTTTCTTTCTCAACTAATTGATTTAAAAACTAAACAAATTACCTAGAAAAACTTTCTTTCCAAGATCTAATATGAAGATAAATTTCAACTATTCTTTCTGATCCACAGAGCTAATTGCTAAAACTTGCATCTTAATGTTACATATTTTAAAATGCTTCCAAGTTGGTAGCCTTTAAACTGCACCAGTCTTTCTAATGCTGATAGTTTTTGAATGAACAATATAAAAATCTGCTTCTTTATTCATAAGTTGTAATCAAAGCATTTTCTTTGCTAATAAATTTATATTTGATTTGTCTTTTTAAAAAGTTTTTCAGATAAACTACAGGTCCTGAATGTAGACGAGTCTATTTCATAAAATAATCATTTGTATATTTAAATTCATATTCATTCAGTTGTTTGTCTGGTTAAACCAGGTCTCTTTTGGACTGTTATTAGCTGTGGAGGCAGATAAGGGTGGTGTATTGATTGGGAACGTGGGGTTTAGTGGTGATGGGTAATCAGTTCATAATACAACAAAATACCAAACTTCAGAAGCAAACTTTACGTCAGTTTGATGGTGTCTAATCTCCGTGCATGTACCTCCCTGAATATAAATAGCTCTAGCATGAAATTTCTACTGGTTTATAGGTTCTTAAGTCACTCTGAAGACACCTAAATAATCACAAAGGAATAAACTGGCAAACTTTAGTTTTCATTGCTCTTATAGGAATTCTGCAGCTCATGTCAAGTCACCAGTGACATTTTTGTCAGCATGTATGTTTTATTGGCTCATGTAGAAATCATTAATTATTGTATTAAACATAGGACCTTAAATCAATTAGGGAAAGATATTAAAGTGTTGGTTATTTTGTGATTTTTTTTTTTTTAAAAGATACATGAAAAGGAAATCTTGAGTTTTGGGTTTTTTCCTTTCGTGGAGAGCTATTAGGCCATAATCACTTATCCATTGACACCATTTAAATGTTATTAAAATGTATTGCAGAAAGCTAGTTTTTAAAATATATTATTATTGACTTTATTACTTCTTTCTGCTATTTTAGAATTAAATTAAGCATGTTTTCTTTTTTTTTTTTTGAGCTTGTATTTTTATTTTCAGTTTTATATATACTTAAATACTTTTAACAAATAGAATCCTCATTTTTCCTACCAGGACTTAAAGTTTCTATGTGGAAAATAAGGTTGCAACAGTGATGCAGTGTGGCATGTTAAGAAGAAGAAAACAAATCTTAAATTTTTAATTTAATATTTACTAAAGTGAATTACTGCATTCTTTCTAAATTATACTGTTCAAATATGTAATAAAGTGTGTTTTTTAACCATCTGCTGACTTTAATAACTTTCTAATCAACTTTTTGTACAGCTTATAAATTTCAAGATTAATAAACCTTTAGAATTGTCAGTGTCTTCTCAGCTCTGAATAAAGTAACAAACTTTTAAAATTAAGAATAATTACATTTTATTTAAGTACCTACTTGATGACTATTGTAGACAAAAGCTCTTATGTGTTCTTTTCTTCGTTATTATAG
Seq C2 exon
TTCTGCAGAATCAGAAGATTTGGCAGTACATTTATATCCAGGAGCTGTTACTATTCAAGGTGTTCTCAGGAGAAAAACTTTGTTAAAAGAAGGCAAAAAGCCTACA
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000116191-RALGPS2:NM_152663:15
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.222 A=NA C2=0.012
Domain overlap (PFAM):
C1:
NO
A:
NA
C2:
PF154131=PH_11=PU(24.3=47.2)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)