HsaINT0137687 @ hg38
Intron Retention
Gene
ENSG00000111344 | RASAL1
Description
RAS protein activator like 1 [Source:HGNC Symbol;Acc:HGNC:9873]
Coordinates
chr12:113104161-113105883:-
Coord C1 exon
chr12:113105714-113105883
Coord A exon
chr12:113104299-113105713
Coord C2 exon
chr12:113104161-113104298
Length
1415 bp
Sequences
Splice sites
5' ss Seq
CAGGTGGGG
5' ss Score
6.92
3' ss Seq
GCGACAATCCTCTTCCCCAGATG
3' ss Score
7.16
Exon sequences
Seq C1 exon
CTGGTGTCCCAGCCAGGGCCCTGTTCCCGCCCTCGGCCATTGTTCGAGAAGGCTATCTGCTGAAGCGCAAGGAGGAGCCTGCCGGCCTGGCCACGCGCTTTGCCTTCAAGAAGCGCTACGTCTGGCTCAGCGGGGAGACCCTCTCCTTCTCCAAGAGTCCTGAGTGGCAG
Seq A exon
GTGGGGTTCCAGTCCACTATGGAGGGCTTTCCAGGGGTGGCCTTTTTCAGTGTGCTGCCTCTTTGTACCCAGGGGGAAACTGAGGCCCACAGTGGGGCAAGGCCCCAAGATGCCATAGCAACTTAACAACGACAAACTCTCAGGACAGGCTCTGCTCACAAGTTCAGGCCAATGTGGGCACAGGACATGGACAGGCACCATCATGCATCCTTCAGAATGTGCACATGCGGTGGCGGGGATACGCCTCCCAGATGTGGATGCACACAGGACAGGGATGATGCTGAGCCTCTCTCCAATGCTCCCACCAGGATCTAGACACATGCTAGACAGACTCATAAAATTGAATGTGTTCACTAGGAACGTGTGCAGATGTTCAGGCACATCCATCCAAGCATTCATTCACTCGTTCATTCATTCAGCAAACATTTATTGAGTGCCTATTATGTGCCAGTGTCCTAGGCACTGGAGATACAGAAGTGAACAAGACAGGTGAAAATCCTGCCCTTGTGGGGCTGGCGTTCATGACTAGAATGCCCCGAGACACGTGCTGGAATCTCCCGAATGGGGAGCTGTGTGCACACCAGTAGATGATGACGGCTAACGCTGAGAAGGGAGCCCACGCTTCCTGTTTCTATTTTATCAGAAGAATGGAGATTCTAGGGGTCAGTTCTCTGGGTTCCAATTTTGGGTCCACCCAATGAGTGACCTTGGAAGCGTCATCTATCCTCTTGCACCTCAGTTTTCTCATCTGCAGGTTGGAGAGAATAACAGAACCAACCCCAGAAGTTTGTTGTGATAATTAAATAAGTTGATCAATGTAAAGTGCTTGGAATCGCGTCCCAAGTACCATAGAAGTGGTAGTTATTATTAACAAGGAAATGGATGCCCAGAGAAGTTGTCACTTAGAGAGGTGGCTGGGCACGGTGGCTCATGCCTGTAATCCCAGCACTTTGGGAGGCCGGGGTGGGCAGATCACTTGAGGCCAGGAGTTCGAGACCAGCCTGGCCAACATAGTGAAACCCCGTCTCTACTAAAAATACAAAAATTAGCCGGGAGCGGTGGTGCACGCCTGTAATCCCAGCTACTTGGGAGGCTGAGGCAGGAGAATCGCTTGAACCTGGGAGGCGGAGGTAGCAGTGAGGCCAGCTCGTGCAACTGCACTCCAGCCTGGGCGGCAGAGCGAGACTCTGTTAAAAAAATAAATAAATAAAAATTAAAAAAATAAAAGGGGATAGGGCAGGACTCATGGAACAGCTCACATGGATGGATGGACGAGCACACAGAGCACAGACTTACAGGGTTGAATGTCCCGCCGCTGGGAACTGACTCCACCTGCTGCACACAACCAGACGGAAGGTGTCCCCACCCCGGCCCTAGCCCCCAGCCCATCCTGCAGCGACAATCCTCTTCCCCAG
Seq C2 exon
ATGTGTCACTCCATCCCCGTGTCTCACATCCGCGCCGTGGAGCGCGTAGACGAGGGCGCCTTCCAACTGCCCCACGTGATGCAGGTGGTGACGCAGGACGGCACGGGGGCGCTGCACACCACCTACCTCCAGTGCAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000111344:ENST00000261729:17
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0016924=PH=PU(40.2=75.4)
A:
NA
C2:
PF0016924=PH=FE(42.1=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CAGCCAGGGCCCTGTTCC
R:
CTTGCACTGGAGGTAGGTGGT
Band lengths:
299-1714
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development