HsaINT0137717 @ hg38
Intron Retention
Gene
ENSG00000105122 | RASAL3
Description
RAS protein activator like 3 [Source:HGNC Symbol;Acc:HGNC:26129]
Coordinates
chr19:15456104-15456646:-
Coord C1 exon
chr19:15456502-15456646
Coord A exon
chr19:15456249-15456501
Coord C2 exon
chr19:15456104-15456248
Length
253 bp
Sequences
Splice sites
5' ss Seq
TGGGTGAGC
5' ss Score
7.23
3' ss Seq
CTGGCTGTGCTGGGCTGCAGGAC
3' ss Score
6.16
Exon sequences
Seq C1 exon
GCGCTGGTGACTGACCTGGGCACTGCGGAGCTGGCGCGCTGTGGAGGCCGTGAGGCGCTGCTGTTCCGGGAAAACACATTGGCCACCAAGGCTATCGATGAGTACATGAAGCTCGTGGCACAGGATTACCTCCAGGAGACCCTGG
Seq A exon
GTGAGCTGGGGGAGAGTCCATGTCAGCGGCCTGCTGGTGAGCTAGGGGACCTGGGTGAAGTTCTAAGAGTCCTTGAGCAACCTGGATTCTGGTAGTGAGTGGTGTTTTGGGGGTGCTAGGATCCTGGGGACAATTGGGAGCTCCCCAAGATGTTGGGTGCCTCCGGAATAACCTGAAGACAAGGTTGGAGGATGGGTGTGGCAGGTTTTGGTGGTCATGGCCCCAGCCCCTATCTGGCTGTGCTGGGCTGCAG
Seq C2 exon
GACAGGTTGTGCGGCGTCTCTGTGCTTCTACTGAGGACTGTGAAGTGGACCCCAGCAAATGTCCAGCCTCGGAGCTGCCAGAGCACCAGGCCAGACTTCGGAACAGCTGCGAGGAGGTCTTCGAAACCATTATCCATTCCTACGA
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000105122:ENST00000343625:10
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.020
Domain overlap (PFAM):
C1:
PF0061614=RasGAP=PU(27.3=95.9)
A:
NA
C2:
PF0061614=RasGAP=FE(27.9=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal3)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CTGGTGACTGACCTGGGCA
R:
TCGTAGGAATGGATAATGGTTTCGA
Band lengths:
287-540
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development