HsaINT0137718 @ hg38
Intron Retention
Gene
ENSG00000105122 | RASAL3
Description
RAS protein activator like 3 [Source:HGNC Symbol;Acc:HGNC:26129]
Coordinates
chr19:15454657-15456248:-
Coord C1 exon
chr19:15456104-15456248
Coord A exon
chr19:15454894-15456103
Coord C2 exon
chr19:15454657-15454893
Length
1210 bp
Sequences
Splice sites
5' ss Seq
CGAGTGAGA
5' ss Score
3.85
3' ss Seq
CATTGCCTCTTCTGCACCAGCTG
3' ss Score
5.96
Exon sequences
Seq C1 exon
GACAGGTTGTGCGGCGTCTCTGTGCTTCTACTGAGGACTGTGAAGTGGACCCCAGCAAATGTCCAGCCTCGGAGCTGCCAGAGCACCAGGCCAGACTTCGGAACAGCTGCGAGGAGGTCTTCGAAACCATTATCCATTCCTACGA
Seq A exon
GTGAGAATCAGGGCCCCAGCAGCTTAGCCCACCCCTGCTTACCATGCTAGCCCCGACCTCCAGTTTAGGGTGGCCAGATAAAATACAGGAGACACTCAGTTAAATTTGATGCAATAATTGGGACCATGCTTATACTAAAAAATTACTCATTTGAACCAGGCATGGTGACTCACGCCCGTAATCCCAATGCTTTAGGAGGCCGAGACAAGAGGATTGCTTGAGCCCAGGAGTTCAAGGCCAGTCTGGGCAACATAGCAAGACTCCATCTCTCCAAAAAGCTTTTTAAAAATGAGCTAGGCATGGTGGCACACACCTGTATTCCCAGCCGAGGCTGGAGGATCGCTTGAGCGCAGGATTCAAGGCTGCAGTGAGCTATGATCATGCCACAGCACCCCAGCCTGGTTGACAGAGACCCTGTCCCAAATAAAAGTAAAAATATAAATAAAAATCACTCCGTTATCTGAAATTCATGTTTAACTGGATGTCCTGAAGTTTCGTTTGCTGCATCTGGCAACCCTATCACCATGCAACCCTATCACCACTGACCCCAAGTAACCTGAGACCCAATTCCTTGTCCTGTAACCACAGTTGATTCCATATCCCCAATTTCATGCCACTGGCTCCAGTTAACATAGGACCTCAATCCTATGACCAGATGATGCCCCAAGTCCATGATCCCTGGCTTTAAGTGACCCTCCACCTCAAATCCCATGCAACTGATCACAGGAGACCTGGGATTCCAATCCCTTGACCTCTGACCCTAGGTTAACCTGCATACCTAATCCCTGACTTCAATCAAGTGACTTCTGACCCTAGGTGACCTCCAGAGCCCCAATCCTACTTTATATCTTGTACTCTGGCCCACCAGTCTCATGTCTAATTATAAGTACATCCAAGCTCATAACCTCTGTCTTCATGTGACCCTGTATCCCCAACTATAAGAGTATTATCCCCAGCGATTGCCATAGCTACACCATAAGCCATGGCCCCATGCTGATTCATAACCCCAAGCATTGTTATCTCAGATATTCCCAATCCTAGAGCCCAGACCCCAGGTTCAGTGAGAAGGAAGCCTGCATGGGCTTCATGAATAGCTCTCTGGAGGATCATGGACCAATCATGCAGTGCTTCTGGGACTCCCAACCTTATGACTTTAACCTTTATGCCCATAGCCTCCCCGTCTGACCATTCATTGCCTCTTCTGCACCAG
Seq C2 exon
CTGGTTCCCTGCGGAGCTGGGCATCGTGTTCTCAAGCTGGCGAGAAGCATGTAAAGAACGTGGCTCTGAGGTGCTGGGCCCCCGACTGGTGTGCGCCTCCCTCTTCCTGCGGCTCCTGTGCCCTGCCATCCTGGCACCCAGCCTCTTTGGTTTGGCACCAGACCATCCAGCACCCGGCCCAGCCCGCACCCTCACACTGATTGCCAAGGTCATCCAGAACCTCGCCAACCGTGCCCC
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000105122:ENST00000343625:11
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.020 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0061614=RasGAP=FE(27.9=100)
A:
NA
C2:
PF0061614=RasGAP=PD(44.2=95.0)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GGCGTCTCTGTGCTTCTACTG
R:
GCGAGGTTCTGGATGACCTTG
Band lengths:
358-1568
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development