HsaINT0139890 @ hg38
Intron Retention
Gene
ENSG00000205517 | RGL3
Description
ral guanine nucleotide dissociation stimulator like 3 [Source:HGNC Symbol;Acc:HGNC:30282]
Coordinates
chr19:11416836-11418784:-
Coord C1 exon
chr19:11418671-11418784
Coord A exon
chr19:11417060-11418670
Coord C2 exon
chr19:11416836-11417059
Length
1611 bp
Sequences
Splice sites
5' ss Seq
CAGGTGAGG
5' ss Score
10.07
3' ss Seq
CCACCTCTCCCCTCCTGCAGGCT
3' ss Score
11.62
Exon sequences
Seq C1 exon
GCACCGCTGCAGGACTGGGGTGAAGAGACCGAGGACGGCGCGGTGTACAGTGTCTCCCTGCGGCGGCAGCGCAGTCAGCGCAGGAGCCCGGCGGAGGGCCCCGGGGGCAGCCAG
Seq A exon
GTGAGGAGGGGGTTTGGTGGGTGGCGCGGGGCCGGAAGCGACCAGTTGAGGGCGGAGCTGGAGAGCCGAGCACAGGCCGCCAGGTGCAGTGGGCGGAAGGAAGGGAGGGGCTCGGAGGCGACCAGATGAGGCGACCAGGTAGAAAGGGGACTGGGGGCGGCCAGGTAAGTGGGGGGAGATCCAGGGAATGGGGTGGGGCCAGGCGATGGCCGCGCAGTTCCCGAGAGGAGCCTAGGGACAACTTGGTAAGGACAGAACTGGACGGCAGAGTTGGGAAAGGCAGGTTTAGAGGGCCGGGGCTGGAAGGTGGAATGGGGTTGGTTTAGAAGTGGCTAGGTGAGGGCGGATGGGGCAGCCAGTGAAGCGCGACAGGAGGGCTGAGGGAAGCCCTGGGTGGAAAAGAGTGTGTGGGGCGGGGGCGGGGGGGTGGGGGGAGGGGACGGGAGGGGGAGGGGACGGGAGAGGGAGTAGGGGACAGGGCATGGGAGAGGGAGGGTTTCCAGGGCAAGTTGCAGGAGCTATTTGTGGATGGGGAGGAACAATAACTTCAAGCGGGCAGGGAGTGGGGCACACACCTATAATCCCTGCGCTTCGAGAGACCAAGGCAGAAGGCCAGGAATTGGAGACCAGCCTGGACAACACAGCAAGATTCTCTCTAATAAAAATAAAAATTAAAAAACTAGCTGTGCGTGATGATGCCCAGCAGTGGTCCCAGCTACTCAGGAGGCTGGGGCAGAGGGACCGCTTGAGTCTAGGACTTGGAGGCTGCAGTGAGCTATGATTGTGCCACTGCACCCCAGCCTGGGCAACAAAACAAGACCTGTTTCTAAAAAAAACAAACCAAAACAATAACTCCAAGAAGCCGGGAGACAGAGGAATCACATGAAAGAATGGTGCTACAGGCGGGGCGAGGTGGCTCACGCCTGTAATCCCAGCACTTTGGGAGGCCGAGGCAAGTGGATCATCAGGTCAGGAGTTCAAGACCAACCTGGCCAAGACGGTGAAACACCGTCTCTACTAAAAATACGAAAAAACTAGCTGGGCTTGGTGGCGGGTGCCTGTAATCCCAGATACTTGGGAGGCTGAGGCAGAGAATTGCTTGAACCCAGGAGGCGGAGGTTGCAGTGAGCCAAGATCACGCCACTGAACTCCAGCCTAGGTGACAGAGTGAGATTCTGTCTCAAAAAAAAAAAAAAAAAAGTGGTGCTAGGGGCTGGGCACGGTGGTTCACGCCTGTAATCCTAGCCCTTTGGGAGACTTTGGGAGGCCAAGGGGGGCAGATTACTTGAGGTCAGGAGTTCGAGACCAGTCTGACCAACATGGTGAAACCCTATCTCTACAAAAATACAAAAATTAGCTGGGCTTGGTGGTGTGCGCCTGTAGTTTCAGCTACTTGGAGGCTGAGGAAGGAGGATTGCTTGAACCCAGGAGGCAGAAGTTGAAGTGACCCAAGATCGTGCCACTGCACTCCAGCCTGGGCAACAGAGTGAGACTCTGTCTCAAAAAAAAAAACAAAAAAAAAAAGAGTGGTGCTAGTGATGAATGTGACTAGAGAAGGGGTGCTGTGAGGACCACTCCTGCTCTCTCATGGCCACCTCTCCCCTCCTGCAG
Seq C2 exon
GCTCCCAGCCCCATTGCCAATACCTTCCTCCACTATCGAACCAGCAAGGTGAGGGTGCTGAGGGCAGCGCGCCTGGAGCGGCTGGTGGGAGAGTTGGTGTTTGGAGACCGTGAGCAGGACCCCAGCTTCATGCCCGCCTTCCTGGCCACCTACCGGACCTTTGTACCCACTGCCTGCCTGCTGGGCTTTCTGCTGCCACCAATGCCACCGCCCCCACCTCCCGG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000205517:ENST00000380456:2
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.682 A=NA C2=0.193
Domain overlap (PFAM):
C1:
NO
A:
NA
C2:
PF0061815=RasGEF_N=PU(52.3=74.7)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal3)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CAGGACTGGGGTGAAGAGACC
R:
GCATTGGTGGCAGCAGAAAG
Band lengths:
310-1921
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development