HsaINT0145207 @ hg38
Intron Retention
Gene
ENSG00000188322 | SBK1
Description
SH3 domain binding kinase 1 [Source:HGNC Symbol;Acc:HGNC:17699]
Coordinates
chr16:28317385-28319197:+
Coord C1 exon
chr16:28317385-28317617
Coord A exon
chr16:28317618-28318994
Coord C2 exon
chr16:28318995-28319197
Length
1377 bp
Sequences
Splice sites
5' ss Seq
CAGGTGAAC
5' ss Score
5.56
3' ss Seq
GTTGCTGTTGCTCCCATCAGGCA
3' ss Score
6.32
Exon sequences
Seq C1 exon
GGAGAAGATGAGCGTGGGCTGCCCAGAGCCTGAGCCGCCCCGCTCCCTGACCTGCTGTGGGCCGGGGACTGCCCCTGGGCCTGGTGCCGGTGTGCCCCTTCTCACTGAAGACATGCAGGCCCTGACTCTCCGCACACTGGCCGCCAGCGACGTCACCAAGCACTACGAACTAGTCCGGGAGCTGGGCAAAGGCACCTATGGGAAGGTTGACCTGGTGGTCTACAAGGGCACAG
Seq A exon
GTGAACAAGTGCAGGGTGGCAGGGCTGAGAGGTTGGGGTGGGGCAGGGCTGGGAGGTCAGGGTTGGGGGACATGACCTTGCAGCTGGGCCGGGGCTCTCTGGTGCTCTGTGGAAGCCAGGAGGCAGGGTCAGGGGCCAGATGTAGAGGATGAGGCCTGAGGCAGCCCAGGGGGAAAGAGACTGGGCAGATGGGGCAAGGGAGGAATCCGGGGCAGAGTGGCCAGGGTACAGGATGGGCTGCTGTGGGGCCATCTGGGGTGACTTTGAGACAGCCAAGGGGCTGTGCCAGGAGTGTCTGGGGAGGGCAGGGCTGCCGGCTGTGTCTGAGTATCACCAGCGTCTCAGGGATGTCTGGCCCCAGGAAGGTGGATGGAGAGTGAGGGTGGTTCCTCAGGAACAGGGTGCCACACTTAATGGGTGGTGGAAGGACCTGTGAGGTCAATATTGCAATCACCATCTCTCAGGTGAGGACAGGGAGACCTAGGCCAATTCAGCCACATAGCCAATGCCCTGCAGCTACAGAGGCTGTGAACCAAAACGAGACCCCAGGAGTCATCTCCAGAGCCTTGTCGCTTAGTCACTGAGCTTGATACCTCCCCCACACTGTAGGTCACAGCCGTGCCACCCAGCCAGCCAGGGGCTGGGGCTGTGTGAGCTCCCACAGCTGCACGCGCTTGGGTCCAGGGGCTTTGTGCTAACTGAGGGCAGCAGGAGGAGCACCTAACATGGGGTCACCTGAGCTTTGTTACTTGCTTGCTGTGTGACCTTGAGCAAGTGACTTCACCTCTCTGTGCTTCAGAGTCCTTCTCTGTAAAATAGGGTAACATTAGTGCACAACCCATACAATCATAATGAAGTGTGAGTTGTGAATGTGCAGTGCTGAAGGCAGGGCCTGCGATGTGTAAATGCTCCGTGGACACACATGTGTGCTCCACCCAGCTATGTACCAGATGGGCACAGATGCTTGCCCAGGCACAGAGTTGTGGACACATGCCTTGCAGTGTCTCATTTCTTATTCATTCATCCATTTAGCAAGACAGGAAGCTTAGGGAGACCCGTTCTAGATGGGGTAGGCTGACAAGATAAATAAGCATATGGCGGGCAGGACAAAATGAGAGAGGTGGAGGGCATCACAGGCCCCCTCGCCCCCTCCTCTTGGAGAGCTGCAGAGTGGGTGTAGAAGGCTCAGGTTGACCCTGCCTGCATGGCCTTGGGCAAGTCCTTTCCTCTCTCTGGGTCTGTTCCCATCCGTGAGATGAGGACAGTCATGCCTGCTGGGGACCCTGTTGCACCAGGGTCCAGAGACAGGCATGGGTGCATCCAGTGCGGAGGCACTGGGAGAGGGGGCTTCAACCCTGTTGCTGTTGCTCCCATCAG
Seq C2 exon
GCACAAAAATGGCACTGAAGTTTGTGAACAAGAGCAAAACCAAGCTGAAGAACTTCCTACGGGAGGTGAGCATCACCAACAGCCTCTCCTCCAGCCCCTTCATCATCAAGGTCTTTGACGTGGTCTTTGAGACAGAGGACTGCTACGTCTTTGCCCAGGAGTACGCACCTGCTGGGGACCTGTTTGACATCATCCCTCCCCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000188322:ENST00000341901:2
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion (1st CDS intron)
No structure available
Features
Disorder rate (Iupred):
C1=0.263 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0006920=Pkinase=PU(8.7=30.3)
A:
NA
C2:
PF0006920=Pkinase=FE(25.5=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Cow
(bosTau6)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GGTGTGCCCCTTCTCACTGAA
R:
GGGGAGGGATGATGTCAAACA
Band lengths:
346-1723
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development