HsaINT0146185 @ hg19
Intron Retention
Gene
ENSG00000159307 | SCUBE1
Description
signal peptide, CUB domain, EGF-like 1 [Source:HGNC Symbol;Acc:13441]
Coordinates
chr22:43658726-43687186:-
Coord C1 exon
chr22:43687052-43687186
Coord A exon
chr22:43658852-43687051
Coord C2 exon
chr22:43658726-43658851
Length
28200 bp
Sequences
Splice sites
5' ss Seq
ATGGTGAGT
5' ss Score
10.13
3' ss Seq
TTGTCTGTCTCTCTTCCCAGAGG
3' ss Score
11.48
Exon sequences
Seq C1 exon
ATGTGGACGAGTGTCAGGACAATAATGGTGGCTGCCAGCAGATCTGCGTCAATGCCATGGGCAGCTACGAGTGTCAGTGCCACAGTGGCTTCTTCCTTAGTGACAACCAGCATACCTGCATCCACCGCTCCAATG
Seq A exon
GTGAGTACAGCCTATGCTGACCAGGCATGTCCCCCCCCAGGATGGGCAGCCCCCAGAGTCCCCTTCTCCACATCTCAATTCTGGGGCCCTCAAGGTCAAGGCAGGGAATTTTGGTGGTAGTCTGAATGACTGTTTTGCACGTCTGGTATTGGTTCTGCATGGGCCTCCTTCCAGTTCCTTCCCTCTACCTGCTACACTAGGGCTGCGGGTGTTTCTCGTGTTTATATGTGGGGCCGCAAGTAGCACATGTGACCAGAGGAGCTGTTTTCCTTTCTGAGTTGGGGGCTGGCTGTGGCCAGGAAGAGTGGGGCCCCATTCTCCATGGGCTCCTTCTCCAAAGGGGGCTTGAGGCTATCCAGGCTGTGTGCCAACTTCTCTGTCTCCATGAGCCTGGCAGCACCAGCGACTCCCTGCTGCATGTTCATTGGGTTTCCCGCCAGGAGAGGGTCCTTGTGGTCGGGCGCCTGCTGTTTGGAAGCCAGGCAGTGTGGCAGGCCAGCCTGGGGAGGTGCAGAGGGCCCCAGGAAGACACCCCACCAGCTGGAGCACTAGGTGGCAGACCCAGGCTGAAGTGGAGCCTGGCCACCAGCCAAGCCCAGCAGGCAAAGGAACTTGGTGTTACGGCATCAGTGGTCAGATCCTGGAGTTTCGGCTCAGGGCAGCAGAGCTGTGAGGTGGCGGCAGAGCTGTCCAGAAAGCCAGGACACATGTGCTTGGAGGAGAGAGCCAGGACACATGTGCTTGGAGGAGAGAGCCAGGACACATGTGCTTGGAGGAGAGGGCCAGGACACATGTGCTTGGAGGAGAGAGCCAGGACACATGTGCTTGGAGGAGAGGGGCTTCCAGGCAGAGAACAGCTTTTGCGGAGGCACATCTCTTGCTTAAGATAATGCAAGGGCAGGCATCTGAGGCAGGGCTGTGTACCAAAGCAGAGTGTGCTGTGAGGGCAGGGCAGGAGCCAAGGTTCCCAGGGCCTGGCTGTCGTGAGCTGTCAAGGGAATAAATGTAAGGAAGAAGGCCAGAACTGCCCCAGTTCAGGCACGCCCCCATTGCTGACCCTTAACAAGGAGGAGGCGCTGGAGGCTTGCGGGCATAGAGGGCGTTCCTGGGAAGGTCGCCCCTCTCTGGTACACAGCACCTGCAGAAGGCTCAGAGAGGGGCTCACGCTGAGAGATGGGGAACCAAAGGGCACGCACTGGGCTCCAGGCCAGCCGGACCCTGTGTGAATCCAGCTCCTCCTCTCCCACGCTGGAAGCCTTCCCATGGGCGGCTCTACTGACTGCTCCCCAGATTCCTCGCCTGCAAAATGGGGAAGTGGTGTTACCCGGCAGGGCGTTCAGAGATGGAGCAGGACCATGGGATGAGGTTCCAGCCTCCCGTGAGCAGGCAGGAGGCTGTGAGGTGTGAGTCTGCCAGCCCAGGCATGAGTTTCATTAGAAAACAGTTCCTGAGAAAGTGAAAGCAAAAACATTTAAAAAGTACTCAGGATAATAAAGTGGAAATACTCGAACAGGCTCCTTAGAATTCTTAGTGTTTGTTGCCTCAAAGGCAGGACGGGCCTGCTAATCATGGCTCTGTGGTGTCCCCAGAAGAACAGAAAGCCCGAGCTCCGTGGCTCCTGGCACTTGCTGCTGTCACATTGTCCACACTCCACCCAGGTGGCTCCCGGGCATCAGGAGTTTGTTTTGCGCCTTGTAAGACCTCCCAGTTGTGGGCTGTGGGGCCAAGCTGCCCACGGTGGAGGCAAACCCTATAAACCAGGACTCTGAGCCCAACAGGTTGTATAAGAAGCAGATTGATGGGGACAGAGTGAGCAAGTGCGGGGAGGGGCCTCTGCTTTCATCCAGGGAGGGGAGTTCACAGAGTGACTGCTCTGAGCAGGCTGTAAAGTCCCAGGCCAGGGTGGCGTGAGCCTCCTTTTCAGCCAGGCTGTGTGTGCTCTGTTCCTTTGAAGCCCGGCTTTCTCCCCAGCAGGACTCCAGGTGGAGCTGAGGCCCCTGGTTGAAAGAAGGGTGTGCTGTGGGCAGATCACACCCGCAGCCACAGCCTGTTTGTTACAGGTTTGGCCTGTAAGCATCTGCTGTGCTGAGGAGGTTACAAACCTTAGCGTCCCCTACAGGACTGGGGTTGGGGAGGGGATGACGTGGGAGCAGCGACAGCAGGGGCTGCTGGGGCCACACGCTTACTCTGAGCCAGGCACGGGCCTGAGCACTGCCCAAAGACAAGCTCACTCCACCTTTGCCACTGCCCGGCGAGGCTGGGTTGTGACGCTGAGGAAGGCGAAGCCCAGCGAAGTTAGGGAAGAGGCAGAGCCAGGATCTGAGCCAGGCACGCTAGCTATGGGGCCCGCTCCTTGGGAGGTGATGCGGTGTGAGAGGAAAGAAACGGGTGGTGCAGCAGACGGTGCTGGAGCTGATGAGAAAGCCAGGTGGGAAGCTTGTGGGGAATGTGCCAGGCTGGGCGCGTGCAAAGGCCCTGGGGTGGGAATGGGCACGTGAAAAGCTGAACAAAGGGTGGGACGAAGGAGCAGAGAGCACGAAGCGGGAGGAGCCCGAGGCGGGGAGGTGGGGGCTGGACAACATGGGGCCTGGTGGGCTGTGGCAAGAGTTTGGATTTTGGGTGGAGGGCAGCTGTGGGAAAGCTGGTTGAGCAGAGGTAGGAAGTGATGCTTAGGGGAGAGGGGAGGCCATCTGGGAGAACGCCAGCACTTCCAGGGGCTGGCATCTCATAAATTGTGCAGTGGCTGGTGTTGGGTGGGACCCTGGGCACACATGGCTCACTCCACCCAGATGCCCCAGGTGGTCAGATCCTGATTTTTCAGGAAGCCAGGAGTCCAGCTTTAACCAGAATATGGATTTGGGGGCCTCAGTCCCAATCTGCATTAACCAGCGTGTCGGTTAAAGAAGTGCCTTCTCTCCTTACGATTTTTGTGTGGCCTCTCCTGATTTTTTGATCTGGGCAATGAAATCAGTCCAAAAAACAACAGATAACTTATCAGATTGCTCTCGAACGACAAGGTGCAGCATTCCAGTGGGTTTCCACGGCTGTGTGGAAGTCCTGAAGAGGGCAGAGCAAGCACACAGCACAGTGGTCAGCGGCCCATTAATGCCCATTGGGGAGACAGGGACCTGGGGACTGGGCAGGTTGTCTACCTCTCTGAGCCTCAGTCTGTTGTGACAATTGCCCACCATTAGTGTCAACTGCAATCATGATTGTTATAGCTCAAAATTAGAGCATGTCAGAGGAGCTAAGACTCAGCTTGTTTTGCAGACAAGTGACCTCTGATTCCCATAGCTCCTGGGAGGGCTGAAGGAGACAGAGCCATTTGGCAAATTAGATTCCCCCTATCACCTGACTCTTCCTCATGCCTGTCCAGCTCTTTGGAGCCTACCCCTGAACAGGGAGAAAAGCACACAGGCTGGTTTTGATTAGATGGAACCAGATGCATGAGAGGGGTTGGCCCAGGTCGGTCCAGACTCCTGGCTGAGAAACACAGGGCTCAGCCCGTCTGAGTGGCCCTGCTTTCTAGGCGCCAGAGCACACCCTGGGCCAAGGCATGGCTGCGACCCTGGCTAGGCTTGGGAGGATTAGGTTCTCAGCTCCAGCTCTCCATGTGGCCTCTGCACAGTTACTCTTGCCTCCTTGGGCCTTTTCAGCTGTAAAAAGGGCCTAGCTGTCGAATTTTCCCCATTCGCGGAAAACTGCTCTGGTCAATCAAGGGCAGCACCTGTCCTAGGAGTAGCGACTGATGCAGGCAGCTTCTTCAGGTCTTTAGAACACAGGCTTGATTTGGGGGACACACACAGGCTCCTCCTCTGTGCCCACACTGGGCAGGAGGGAGTCCGAGATGTTGGAATCTGGCCAGTTTCCCTCCACTCAGCACTTCCGAGCACTGCTTCTGGCCCCATGATAGCACCCCCTACCTCCCACTCAGCCCTAGCCCAATAAGTACTGACAATCCCTCCTCTGGCCACAGCCCCAGGGGCCCACCCGCTGCCCCCATCACACACCCTTGTGCCTGGTGTATCTAGAAGGCAGCACCTTCAGGCTCTCTCCCTCTCCCACACTGCTCTTCTTGTCTGTAACTTCTGACGGATTGATGCCACAGGAAGATGTGGCCTCCTGGAGGAACTGTCTCCTTTTCTCTCAATGTAGAATTCTGACCAGAATCGATCCGGGAGTAGAAAGGGTTCTGGAAGGCCTCAGTCTTACTAGCTACGTGAATGCAGGTCACTTGTATTTACCTGCTCATTCATTCATTCATTCATTTATTCGTGTGCCAGGTGCTCTGCCAGCCCCTAGGATCCGAGGCATGGTCCACTGGGAAGCTTTCAGCCTGGACAGGGGATCACATGCTAAGTAGGGGTCCTAAGAGTTCCTGTACAGTCATGAGCTGAGGGGAAACGCTCTGGGGATTCTATGGCTTTGGTCTTCTCATCTGAGCAGCAGAGACGTTCGTGACATGGTCTCCTCCTCCACCTGGTGAACTGTTGCTATTCCGAGGGTCCAGCACTGACACTGGGCCTCACTGGCTGCCAGCAGCTTTGGGTTTGAGATGCCACTGGCCCTCCATGCAGGAGGCTGTCCTGCAGGGCTCTGCTCTGAAGCCTCATCAGACGCCGCCTGTGGGCTGGCCTCAGCCTTGGTGGAAGGCACCAAAGTGAGAGGAAACGTCGCATTGTCTCCATCATTGTAGGAGACAGCACAGGCTCACAGCGGGGCTTCAGGCCCAGTGGCCTAGGCTGGAACCCCAGCTCTACCATGGACCATCTCGTGACCTTGAGCAAGTCACTTAACTTCTCTGTGTCTCATCTGTAAAATGGAGATAGTCATAATACCTGCTTCGTAGGGTTAAAAAGGTATTGAAAAGACAGTTTCAATAAACACGGGCTCTTATTCATGTGATTTGTGACAGATGAGGAAATGAGGCCCTGAGAGGGCAGGGCCTGGCCCAGGGCCCCACAACAAGCCGGCCGCAGAGTCAGGACCTGGAAGCTCTTGGAACGAGGCTCTGCTGACACGTGCCAGGTGCTGCACAGGAGCCTGTTCATTCAGCAGAGGGAGAGGGGAGGGAGAGGATCAAGAGGCCAGCTTTGTCCTCGACAAACTAGCGAGCTGGTGGTCCTTGCACCCAGGTTCATCTGTGCACAAGGTAGTACATGCCAAAACCTGAGGCCCAACAAGATGGCCATCGTCCCTCATTCATCGGCTGAGCTCCCGCACCTATTTGGCCTCGGGGCAGCCCTCCAGGGTGCCCAACCACCCATCCTTCCTGCGGAGGTTTGAGTACACCTGCAGAGGTGTCCCTGCTGGGCACAGGTAATCAGGAGTCACAACACAGAGGGAGCACCAGGGCCCTGCTCCTCACCCCGCCCTGTCTACTGACAGCTCCCGCACTTAGTCCCCTGTGAGAGTATCCCACCCACTGGACAGCCCATTCTGAGCTGAGCCCTCAGGGAAAACTGTTGGGCTCTGCCTCTTCTGTGCCCCAGTGGCCACCTCTGTCCCCCGCCCCCTATTGTTGCTGGCGGCAAGCTCCAGAAAGTGGTTTTCTGCCTCATGGTGCTCGTGTCCCTGCAGCTTGGGAGCTCCCTGTGGGCAGGGACTATGTTCCCCACATCTCTGAGTCCCACTGCCAACTTGGGCCTTTGGAAAGGACAGAGAGGGGAAGGAAGAGAGGAAGGTGGGCGTGGGCAGAGCCAGGATGGGTCTGGGAACAAGGCAGGGTGGTGAGCAGTTCAGCGTGGACACTGAGGAGCGTCGGGACAGCACTCAGTTCACAGCGCCCTCAGGTCGTGCTGTTAGATATTGGTCAGTGTGGGCTGGTGGACCATGTGGTTGGGCCAGGCAGGGGGCCAGACAATAGGGGTCCTCTATTGATGAGAGCCCCCATTTGGGAGAAATGAGGCCACGTGCACAGAAAGCCTGCTGTGCAGCTGCTCTGCTGGGGTTTTATGCACTGGAACAGGCCGTGGGGCAGCCTGAGGTTCTCCCCGCAAGGACTGCATGAGTTTACCCAAGTGCGTTTCACCTTCTGGTTAACGTTCGGAGTTTGTTTAAACACGTGCATAAATACGTGTAGGAAACCGCATTGCCCTCCCTCCACAGGCATTCCTCGTGGGTCTCGAGCCCACTGTTCACAAAGCTCAAGACTTGGCATCAAGAGTGATGTTGTCCTACAGCCAGGGTCAGAGGTGGGGGCCAGCAGTAGGAAAGCTTGGCATCAGGAATCAGTCCCTTTGTGTGTAATGTGATGATGATGATGACGACGACGACGACGACGATGACGATGATGATTGCAAGAGCTGCATCCAATGCATGCTTGCGTGTGCCAGGCCCTGCTACCAGGCACTTTCCATGCATTTCCATTCATTGCGTCCTTACAGTGCCCCATTTTCCAGATCAAGAAACTTGAGGCACTGAGAGGTTAGGGAACTGCAGGGTTGCCAGTGGCTTTGGGGGATTGGAGGTCTGCCAATCTGGCCCCAGAGCCTGGGCTCCTGACTGCCTGATAGTGAAGACAGCAGCAATGGGGAAGGTTCTGGGACCCCTCTCAGTTGTCGGCCCAAGTATGGTGAGACTCAGGCGGGGCCTGAGGTTCAACGGAGATGCCTTTATAGCTGGCACCACCTGCAGCTCCAGGTACCGAGTATGCCTCTTTAAGCACCTAGAGTTCAAAAGACATCTTGTGGTAGAAATTTTCTGCAGTGTGGCACGCACTTCCCTTCTCCCTTCACGGGAACAGCCTGAGTCGGCTTGGCCTCTTTCTTCCTACAGTTTAGGATTCTTGTTATGAACTCAGTTACGGAGACAGAAAATGGTTGCTAATGTTTATCCCCACACTGAATGTCCCCAGACCTCTGGCCTAAAAGCAAACGCTTTTCTTTCGACACTGCTCTTATTAACTGTTACATACCACTGTGTTGTCACGGGTCTTGCTCTGAAGACCACGGCCGTGTGTCTCCATACACAGACCAGGTAAGAGCCTGCGGGCTCGGGCTTGCTGATAGACTGCCTGAACTTTAGAGCAGCTGCCGGCCTCATGGGAGCCATTGCCACTCATTTCTGAGTATTTGCTGGATGACCTCTGGTTAAATTTAACTTAGTTATTTTGCTTATAAAACCCATGCTTGAAGTATTTTGGGGATCCATTCATTTCATCTGTAAGTTTGCAAGGGCAAATACCTGATGATAACTAGAGTCAAAACAATAGGATTTTTTAGAATTTTTTATTTTGAAATAATTGTAGATCCATAAGAAGCTGCAAAAAATAGTGAAGAGTGGTCTCAGATGCCCTTTACCCAATTTCCCCCAATGGTGACATCTTACGTCACTAGAGTTTAACATCCAGACCGGTAGCTGGACGTTGGTACAGTGTGTGAGTGTGGCTCCACGCCATTTATGACATACGGATCCACATCACAACCACCGCAGTCAATAGTTCGCATTTAGTTATAATTGAACAATATCCAAATCAGTACACTTGTGAGAATGAAAGGAGATACTATTATTAATTATGCCAGGGCTGTGGATATCAACTGGGACTGTCCCAGGCAAAGCAAGACATTGGGTCACCCTAATACTGCTTCATTTGACCCCTCGAACCCTCAGATGGATACTAATATTATCCATTGCAATTCCTTGAACCCTGTGAGCTGAGTACTAGCCGCTCCCATGTTGCAGATGTGGGTCAGAAGCTCACAGAGGCAAACAGTGTGTCCAATAGTGGCAGGACTGGAACCCAGTGGTCTGGGTTCAAATCATGACCCTCTCCCACGGCTGTCTGTCAGTGTTTAAAGGAATCACAACCACCCCCATGGATTCCCCCTTCTTTTTTCAAGTGTGGAAATTGGGTTCTAAGGAGAAGAGGAACCTTCCTGCCCAATATGCTGGTCAACCTGTGGTCCCCAAATCTACATGTGCCTGGGCAGGGCGTGCTGGATGAGGAGCAGGGCCAGGGGCTTGGCTAGCGGGCTGTTCAAGGCAGAGGAAGCTGAGCTCAGGGCTGGAGCCAGTGGGATATGGAAAGGGGTTGGAGAAGCCCACAAGAGGCTGGGTGTCGTGGCTCACGCCTATAATCCCAGAACTTTGGGAGACCGAGGTGGGCAGATCACTTGAGGTCAGGAGTTTGAGACCAGCCTGGCCAACATGGAGAAACCCCATCTCTACAAAAAATACAAAAATTAGCCAGGCATGGTGGCGCACTCCTGTAATCCCAGCTACTTGGGAAGCTGAGGCAGGAGAATTACTTGAACCCGGGAGGCGGAGGTTGCAGTGAGCTGAGATCGCGCCATTGCACCCAAGCCTGGGTGACAGAGTAAAACTCCATCTCAAAAAAAAAAGAAAAAAAAAAAGAAGCCTGCAAGAGCAGGTGGCTTCTGAGGTGGTGGCCAACTGATGGAGAGAAGGTGGGTGGTCAGCAGACAGAGGGGCCAGAGTGACATAGGCAGGATGCTGTTGGGAGGATTAAGGGGGGAGATTGGGTAGCAGCAGGAGTTTGTGGTAGAAAGAGAGGGCAAGGGGCTGGCAGCGTCATCTGGGCCCAGACCTTGGTGGACAGCAACGGATTGGAGGCAGCTGGCCTTAAAAAAGCACTTCAAGTAGGACTCTGGAGACAGGGAGCCAGAAACCCTGGGGAGAGGCACAGGCCAGTCCCGTCACTTTCCTGGAATGATGTCTGGAGCAGAGAGAGTCCTCAGATGCCATCCACCGTCCTGCGCCATCTGACTGCAAGCAATTCCGTGGCTGTCCCAGGTCCACAGCGCCTGGAGGGATGGGTGCCCGTGTCCATCCTGGTGTCTGTTTGTTTCTCTACACCATGGGCCTCACTGGAGGGTGCTTGAGCCTCTGCCCTGTGCCTGACACTTTTCCTGTGTGGTTGCTTTTGATTCACTTGCAACCTAGCAGAGACCCTGGGGCCACTGCCTCTCCCGTCCCCGGTGCCCTTCTCAACTCCCTTCACCCTGTTGACCGTCCAGCTGCTCCCGATGCCTGGGTGCCTCCTTCAGGCCAGCCTGTCCTTGCACCGTGGCCAGGGTTCCTCTGACACCGAAGATTCCAGCTTGTTCCGGTTGGCCAGAGGAGTCCTCGTCCCAGCAGCTGTGGTTACCTATGGGAGACAATGGGCCCAGGAGCCTGAAGCCAGGCCCAAAGCTGGCGGAACTCAGAGGGACAGGACCCTGTCTAGCAGGAATTTGGACTGTGCCGTGACAGTGAAGGGTGCCCTGTCAGCCATGAGGAGAAGGAGAATGAGCCCATTTTAGGAAGATCACACTTGCCTCAGTTGTACAGGTGAAGCAGGGAGTGGGGCCAGAGAGAGCACTGGAAGCCATCAGGGTCTGGAACCCATATGGGGACAGCAAGGGGAGAGGGCAGGATGGCTGAGGGGGAGACGACGGGAGGATGGCCAGGGGAGGTGACAGGGTTGCTGAGGAGGAGGTGACAGGAGGGTGGCTGAGAAGGGAGGTGACAGGAGGGTGGCTGAGGGGGAGGTGACAGGAGGGTGACTGAGGGAGGTGACAGGAGGGTGGCTGAGGAGGAGGTGACAGGAGGGTGGCCAAAGAGGGAGGTGACAGGAGGGTGGCTGAGGGAGATGACAGGAGGGTGGCCAAGGGAGGTGACAGGAGGATGGCTGAGGGAGGTGACAGGATAGCTGAGGAGGAGATGACAGAAGGGTGGCCAAGGGAGGTGACAGGGTGACTGAGGAGGAGGTGACAGGAGGGTGGCCAAAGAGGGAGGTGACAGGAGGATGGCTGAGGGAGGTGACAGGGTAGCTGAGGAGGAGATGACAGAAGGGTGGCCAAGGGAGGTGACAGGGTGACTGAGGAGGAGGTGACAGGAGGGTGGCCAAGGGAGGTGACAGGAGGATGGCTGAGGGAGGTGACAGGATAGCTGAGGAGGAGATGACAGAAGGGTGGCCAAGGGAGGTGACAGGGTGACTGAGGAGGAGGTGACAGGAGGGTGGCCAAGGGAGGTGACAGGAGGATGGCTGAGGGAGGTGACAGGATAGCTGAGGAGGAGATGACAGAAGGGTGGCCAAGGGAGGTGACAGGGTGACTGAGGAGGAGGTGACAGGAGGGTGGCCAAAGAGGGAGGTGACAGGAGGATGGCTGAGGGAGGTGACAGGGTAGCTGAGGAGGAGATGACAGAAGGGTGGCCAAGGGAGGTGACAGGGTGACTGAGGAGGAGGTGACAGGAGGGTGGCCAAAGAGGGAGGTGACAGGAGGATGGCTGAGGGAGGTGACAGGGTAGCTGAGGAGGAGATGACAGGAGGGTGGCCAATGAGGGAGGTGACAGGAGGGTGGCCGAGGAGGAAGGTGACAGGAGGGTGGCCGAGGAGGAAGGTGGTGGGGATGTGTGAAAGAAAGGTGACAGAAGGAGGGCTGATAGGGGAAGTTGGTAGGAGCATGGCTGAGAGAGGAGGTGACAGCGTAGCAGGGGAAAGGTAGCAGGAGGATGTCTGCAGGGGGAAGGGACAGCAGGATGGGTGAGGGGAAGGGACAGGAGGATGGGTGAGGGGAAGGGACAGCAGGATGGGTGAGGGGAAGGGACGGGGATGGGTGAGGGGAAGGGACGGGAGGATGGGTGAGGGGAAGGGACAGGGGGATGGGTGAGGGGAAGGGACAGGAGGATGGGTGAGGGGAAGGGACGGGGGATGGGTGAGGGGACGGTGAGAGACTTGGTGAGCTGACTCTCGGCAGAGCCCTCTGTCTGCCCCGGGTTTACACTTCAGCGAGGCCTGTTACCCGCGTCACATAGGTGGGGAATATTTAAGTTTCGGTGGCTCTGGACAAGGTGGGGCCTTGTTCTCTTCGTAGCGCAGAACGCTGGAGGTCTGGGAGACCTGGGGCTCAAGGCAGGGCCCACTGGTCTCTACTTTGGAAGAGGCAGACAGCGCCGAACCCTGCCCAGCGCCTTGCTCAGCATCAGATTCATGCGGTCCGGGAAAGCCTTGTGCAGAGGGCCGCTGCCCACCTTCCTCCTCCTGACTGGCTGGCTCAGGCCTGGCCCAGCCTGGGCTGTAATCAATTGCAGGGACTTGATTGGCTTGAGTGAGGAAAAGCTCAGTATTCAAGGCTTCATTGAGGCTTAGGAGCTTGGGACACTTGTGGAGTTTCAGATCTCCCTAGGGGACTGGGGACATCAGGATTCTTCTGCCGTCTGTACTGCACTTTAGTGACCACATGTCCAAGCCTCTGCATTCCACCCCCTTGGGTAGTACTTGGAAACCCCATTTTTGTGCCAGGGCAGGTCCTTTCGGAACTCACAGGCTGTAGGAGGGTCCAACCTGAGGCAGGTCCCGACCAGACAGTGCGTGGAGGGCTGTGACAGAAGCTGGACAGGGGCTGTGGGAGCCCAGGAGAGCATGCCCTTGCCCACGCCATCAGTCAGCAAAAAAGATTGCCTCCTACTTCATTCCTGCTTCTATAACAGAAGAGCTGAGACTGGGTAATTTCTAAAGATAGAAATTTACTTTTCACAGTTCTGGAGGCTTGGAAGTCCAAGATCAAGACTCTGGCAGATTCACTGTCTGGTGAGGGCTGCCGCAATAGGGGTTCAGTTTCAACATCATTTTGGAGGGGACACAATCATGCAGACCGTAGCACATGCTTACTCTGTGGTGGGCTTAAAAATAAAGGTTTCTTTCCTGCTGGCACTCAGCCTCCTAAGTGGTTGGAGGTGAGGCCCTGCACAGCATATGCACCGAGGCGGCCACTGTCAGAAGCACTGCCAGAGAGCAAGCCCACCCTGCCTCTGGGGCCTGAGCCCCCTGTTCCAAGTCCACAGCTGTCTCAGGACTGGCTGGGGGCTCCTTGACAAAGGTTACCTGAGAGTTTTAGGGTACAGGTTTCCTGGGGTTGAGCCAGAGCAGAGACCTAGTGTTTCTCCCCAGCAGCGTCTGGGGCAGCCTGTATCTGAAACCCTTGCCCTTAGCCTCTTTCCCACCCCAGACTCTAGTCCTGGGCCCTCCCAAGAGCCTCTTCCAGGCTGGTCCTCGAGCTTCCTCTTGACTCTGTCTTCCACTCTGCCTCTCCCACTCTGGCTTGTCTGTGGCCTGCAGGCTGACTGGACACTGTCCTTCCCCCAAACCTGTCTCAGCCCACAGGTGTCCTCAGGAGGCCCAGCCCCACCCTCCCGCAGCTCAGGTGTCCTCGACAGGCCCAGCTCCACCCTCCTGGAGCTTTGCTGTGGTTTCCATACAGGGTCGCCTGATGCTCACAGCCACCCTGTGACATGCTTTGGATAAGTACTAATGTCCCCATCATGGGAGGGAAAACTGAGCTTCCCTGAGCTGCACTGGGGGGGCAGGACTTCAGGATCAGGGGCTGGATTCTGAGGCCAATGTCAGTTCTTTTTGCCCTGCACCATCCACTTGCAGACTCAAAGAAACAAGCCAATGGACAGAGACCCATGGGCCCTCCTGAGCCACCTCAGCCACATATTGATAGGATCCTATCAGTGTGCCTAGCTGTCAGGTTCCTATTGGCTCCTGGGACGGGATTCCTATAGGATCTGGGCCAGGCCTTGACCTGAGGGGCCCTAGCACGGCTCCTGCAGGGCCAGAGACATCCCCTGCCCTGTTCCAGGGCTTTCCATTATCAACTGTGAGTGCTGGGGCAGCACGGCTAGGAACTTCCTGTTTAAAGAGAGGGTGTGGCCATGCCTCCGAATCCCATCCCAGCCTCAGCACCTGCCTTCTTCAGCCACTCCTTGGAGAAGATCAGCCAGGCAAGGGCGCCAGGCAGGACATGTGGGGTTGCAGGTTCTCCTCGCTCCCTTGCCTGCTGCAGACCAGGTGGACAGGAGAATAAACAGCTCCCTTGCTTACTGGAGAGATTTATGGTGCTACCGGAGGAGGCCTGTCCTGGCCCTGTGCGGTCCGGAATGGCCCTCAAGGTGGGGACAATAAATCCAGCCCATTATTTTTTATGAGCCTCCCACTCCATAAACAACTCTTTCGGCTGGTAAGCCCAGCTTCACGCCCCTCTCCTGGCCTGGCCTTGAGCCGGCGCCAGGGGCACCCCCAGTACTGACTTCACATCAGTGGTATAAATTTCCCCTAAGCTGCAGAACTTTCAAATCTCCCAGAGTTGTGGGTGCAGGGCAGGGAGAGCTGCAACCCAGAGGGCTAGGCCAACAGGTAGCTTGCCCAGCCCTGGCGTCCTTCTCTGCCACAAGTCCTGGGGCAAACATTCATATATTTTATGACAGAATTGTTTACGAGAATTAAAATGAGATCGTATATACAAGACATCGCCTCATGTAGAGCCCGGTCCAGATCACTAGAACTGTGCAAAGCTGTCATACGCATCATAGCTGAGCATAGTGCATAGACTCTGACACGAGTCATCAGATCCTGAGAACAGTCTGTGTCATGTAGCTACCCCATTTTGCAGGTGAGCAAATGGAGGCTGAAAAGCAAAGAGACTTGTCCGTAGTGAAGAAGTAGCAAAGCCAAGATTTGCACCCAGGCCCAACCGCCTCCTAAGATCAAAGACACTTGATGAACCAATGGATGGGGGGCCAGGGGCAGGGGTGCTGTGCAGCCCAGATGCCCTGTGACACAAGGAGCCCCTGTCTCGCCATGCTGCCCTCTGCCTAGGGCTGCGCTGCCGTCTTTTGCCTGAGTTAGTGCGGCAGCTGCCTCACAGGCCTCCCTGCCCCGCAAGCCTTCTGGTAGCAGCCAGAACCACTGCTCTGCCCAACCCTCTGGCTCTGTCATTCCCCACTCAAGACCTTCCCATGGCTCCTGAGAGGAATGTGGTTCTCTGCAGCCTGTCCTTGCTTGGCATGTCATGAACCAGCCATAGTGAACTTCTCATCCCGGCCTCTGCCCACACAGCTCCCTCTGTCTGGAACTCCCGCTCATCCTGACTGACCATCGCTCACTGAGAACCCTCTACACCTTTTCCCCGCACACCTCCTGATCCCCCAGGTGGAACCTACGCATCCCTGCCTCTGTCTCATTCGGCCTCCACCCTCAGCCTCCCTGCCCTGTCTCTCATGTCTCTGCTCCCGGGCCTTTCTCCCCCAAGTGAGGATATGCCCTTGGACACAAGGACCCGCTGGCCCCCCAGTGTCCAGCCTGGGGTCTGTAGGGAGCAGGCAGTCAGGAAAAGCTGAGGCGAGGTCATGGAGTTGACGTGCGTGAGAACCGAAAGCATGCTGCCCTGGAGGGAAGCTGGCCTGCACGCCTGTTCTAGAGTGAAGTAGCAGAGGCCCTGGAAACACCATGTGTCCTGTCAGAGGTCACTTAGCATGTTGGGGGCAGAGCTGGAACTTGTCCCAGGCCCCTAGGCTCCAGACCAGTGCCCACCCCCTACACCGTAGCCCACAGCCTGGCTTCCCACCTGGGGTTTGTGGGCACAGGCCCTACGCATGGAAAGTCATGCAGATCTGGAGTGTGGGTTCGGAAACCACCGGGCAGATGCCTGGTTGGCAGAGTGGGGAAGCAGCCGAGGTCATCCTGGGTCATTAGGGAGTGGTGTGAGCCCTCCCTAGCCTCATTAGGGAAATTGGGTTGTGACTGTGGCCACAAGGCCAATCTCCTGGTGGGACGTCTGCCTGGCCACCCCTGGCCGCAGCATTCCCCAGGTCCTCGTCACCCGCCTGAGGCCAGCCAGGTGGGTTTTTGTCTCCCGGCCTGGTGGCTGCTTGATTATGTCACCAGACTCTTTCAGCATGTACGTCCCATGGGACTTCTTCCCTTCCTCCTCAGCCCCCGATCCTGGCTCCTCCTCTGCCTCAGCCCTCTCCTAGCTCTCCCCTAAGCTTCTTGAGTCTCCTTGCTGACCAGCAGTGGCCACTTCTCCAGCTCTGACCCCAGTACCAACTGTCCCCTAGACGGGGACCCCAGCTACAGAATTCCCACCTGCCCAAAACCAAACGCAGCATCTTCCCATCCTCCCAGACCTGTGCTTCCTAGCGCGTCCCCCATCAGTGGGGCACCAGCGCTGGGGTGCTGCCTTCACCCTTCCCCTGTGTGGCTCCCACATCCTAGTGTGACCGGATCCCACGTCCGAGCTCTACTCACCTCCCAAACCCAGCCAGCTTCCTCACCCCTGTTGCCCTGCCTTCTTCAAAGGTTGTGGTTGCTAATTGGTGTCCCTACCTCCGCCTCATCCCCCTTCCCTCCTGCATCCTGCAGCCGGGGCGCTTTCTCCGCCCCCCTCCGAGTTCCTCCATTGTCAGGCACTGCTGCCTTCCTGCCTCCCAAGGCCTCCCACAGTCCAGTTCCTCTCTCCTGGTTCCTCCCCATCTGCCTGTTGTTCTCCCTGTTACGGCACACGTGCCCTTTACTGATTACAACCTCGGTATGTGTCATCCTCTGCCTTTACTGCCATTTCCCATTCCCCTCCCTTCCTGGAGAACTCTTAGTCATCCATCAAAACCCAGCGCACTTTCACCTCCTCTCTGAAGCTGTCTCTGACTCTTAGGCAGGCGTGCACGTCTTCCTCTTTACTTGCACTCATGTGTTTGAAATGGTTCAGCCCTCTACTGCAGGACCAGTCCATGAGCTCCCAAGAAGGGCAGGGATGTGTTTAAGTCATCCTTGTGTTTCTCACGTCTCACACAGGGCAGGGTGCAGAGGAAAACATGCCGCATGGGAGTGTAGAGGAGATGAGACCATCTCATGAGGGACTCATGCCCGAAGTGTGTGCATCATCCGTTCACAAAGTGCCTTCACACCCCTCGTGCAGAGCAGTGTGCCCAGCCCACCGCCAGGAGAGGGACGCCCAGCGCGTCGTGGTTTGCTGGGTCCTGCACTGCTGTCCCACCTTGCTCCCTTCCACAGCTGGTCAGCTTGCAGGTCTGCCGGCTTCTCTCCACGAGGCCTCTCCAGCCCCAGTTTGTCTGTCAGAAGCGCAGAGACCCCCAGCCTCACTCCCCAGGCCTCTGCATGGGCTTGTTCCTGCTCCAGAACACCTTTCCCTCCCGCTGCCCAGCCTCGCCTCCACATCACAGAGCGCCTGACTCCTGTGCCCCCAGGGCACATCACAGATCGCCCACACGTTTGTCTGTTGAGTGCAGCGACAAGTCACCAGACTAAGTTTGAGTCGGTGGCGGGAATTGGCTTATGTCCCCAAAGTGGCTGTACCTGCCGATGATCCAAACGTACCTACTGTGCCCCGAGCCCATGAGCCCCTTTTGTCCTCGAAGGGCCATGAGAAGTACCCGCTGCCGCCCCTCATGCACAGCTGAGGGAGAGGAAGTGAGCGCCACTGCTTGTGACGCAGCCGGGACTCCAGCCCCAGGCTGTGGCTCTGCAGCCCCTGCTCCTTTCTGCGGCATGTGGGTGGACAGTGGTGGAGAGTCACTGGCTGGGGCTCGGGGACGCTGCTCACAGCCTTACAGATCCTCCTGTTCGTGTGTCCACAGTGCTCTTACCACTGTCTCCTTCCGGGTTCCCAGGGCTGCTGTGGGAACACTTTTGGGATGCTACCACCTTGGCCCCCATGCCTGGGCGCCCTCCATCTCGTCACCTGCTGGAAAGGAAAAACAGACCTTTTCCCTGTTCGTGGCAGGCCATGGCCTGGGCACCTGCCTGAGCTCTCTGGCAGTAGGAGCTAAGGGTGGCACTAGACAGCCTGTCCGTCCGCCATGGCTTCCTTTAGGGTCCCTGTGGAGGGCAGGGCAGGGTTGCCAGATAAAATACAGAGTGCCCATTTAAACTGGGATTTCAGATAAACAAGTAATTTTTTTTATTATAAGTATGACCCATGCAACTTTTGAACATACTTATACTCAGGAAGTATTGATTGTCCACCTGAAATTCAGATTGAATGAGGCGTCCTGTATTTTTATTTGCTAAACCTGGCAACCTGAGGGAGGAAAGAAGGACACCTCCAGCCTCCCGGGCCTTGAGGGAGTAAAGCTCAGGAGGTGAGTGAGTCTCTTGACTCTTGACTTCTCTGGTGCAAGACCTCAGGTCCGTGGGGGCAGAAAAACTTGATTGCGGTGACACCTAGTGACCAGCCTGGGAAATTTCAGGAATCAAGGGAGAGGAACGGGGAAGAAACGAGGCAGGGCAGGGGCTCCAGGTGAGGAGCCAGCAGGCAGGGGAGAGGGAGCGGGCCAGCCTTACAGAGCACCCCCTGCAGCTTGAGGGATCTGAGCTGGAGCCCATCACCTCTGTTACTGCCCTTGAACACTCTTACAAAAGAAAGTTTTAAGCTGCGCGTGGTGGCTCACACCTGTAATCCCAGCACTTTGGGAGGCCGAGGTGGGAGGATCGCTTGAGCCCAGGAGTTCGAAACCAGCCTGGACAACATGGTGAAACCTCATCTCTACAAAAAATACAAAAATTAGTCAGGTGTGGTAGCGCACACCTGTAGTCACAGCTACTCCAGAGGCTGAGGCAGGAGGATTGCTTGAGCCCTGGAGTTCAAGGCTGCAGTGAGCTGTGATTTGATTACACCACTGCACTCCAGCCTGGGCGGCAGAGTGAGACTCTGTCTCAAAAAAAAAAAAAAAAAAAAAAAAGAGGGTTTTAGTCTCCCCACTTTATAAATTAGGCAACAACAAGTTCTAAAACCACATGCCTTAGAAAGGGCTGGGATGGGGACGCAAATCAGCGCTGTCGAATCAACCTGCCCCACCTCGGTGTTGCCCAACCCATAGAGCTTTCTGTGGCTCTGCAAATGTTTCTTGGTCCTCCCAACTGTCAGAGACAGAACCACCTCCCATTTCACAGAGGCAGCTTTCTAGGGGTTCCCGGTGCCAGGACTGGTCAAGGCCCTGGGGTGGGGAGAGGGTGCTGAAGGGAGGCTGGCATCCATCCTGCTTTCGGAGAAGCTTGCCAGGAGCCAATCACAGTCCCAGCTCTGTCTGTCTCCATCTGTGTACACAGTGCGTGCCTGCCAGTGAACCGCATGGCAGTGACTGGGTCTCAAACTGAGAATGAGCGTGTGGGGTTGGACACCCTTCCTCCTCGGTCTCAGCCCAGGGCCTGCACACAGCTGGTGCTTAGCAAAGGTTTGTCAATTGAGGGAGTGAAGGAATGCGTGAGCTGAAAGGTCAAGGGCAGCAGTCCTTGTGTGCCACCTCTTGATGTGAAAGAAAGAGCGCTGAGCTTGACCGAAAGTGGGAGGCTGCATGTGAACTCTGCACTGACAGCTGCGTGACCAGGGCAAGTCACAGCCGCGTGACCCAGGACAGTCACTGTCTCGTGGGCTTCAGCCTCCTCAGTGGAAATGGAGAGGCTTCACCTAGATGCTCTCCAAGGCGCCTTCCAGTTCTAGCTTTCCAGAAAACCAATCCATTCTGGTTTTTGCTTGCGTGTAAACACAAAGCAGGACAATTTCTCTCGGAGCTGTGGCCCATGTCCGTGCCCGGTGAGCTCATCAACCAACCACCTTGCAGGTGTTTATTGGGCACCCATTCGGGCTTCACTGTGGTCCGGCCCCTAGGAGAGCAGATCAGGAGGAGGCGCAGACAAGGAGCGGGCTGGTTGGTAGAAAGGCCTGCGCCTGCCTGGAATCCTGGGGCTGGAAACCAAGGAGGCACTCCCTAAATATTTGTGGAATGAAGGGGCACGTAAGCACACAAGCAGTTGAACGTGGAAGGCGTTGGGAGCCAGATAATACAAGATGTGGACTCTTGTGGCTGGAACAGCTGGGTGGTGAGTGCTGAGCCAAGGCCTGTGCACACCCAGGACGACTAGTCCTCTGGGGCCTGGCAGGAGCCTTTGAACCCTGAAAGAGGGCCCAGAGTCGGTGTCAGAGCAGAAGGGACGGTGCTGCGAGCGTGTGGAGTGGGTGGGAAGGGGACCAGGCAGAGTGGGCCAGCTTCTTTGCTGGGTCACACACCCAGCTGGGACCCAGGACCCCAAGAGGCTCTGGGGGATAAACTCTTTCCCCTACATCCAATATGGCATATTGGTCAAAGCAGAGGGGGCAGTGAGAAGGACGACGAGAGGAGCAGAGTTCCCTTGAGGGACCGTCCAGGCTGCCAAGTGGGTACCAGGGCTGATGAGGTGTGAGGTGAGCACTTAATGGAGGGGCTAGAACCCCTTTGGGCCTGCCAATGGAGTGGCCACCAGGGCATCAGCTCCCTACTCCCTCACACAAGGTAGAAGACCTGGGGCGGCAAGTCTCTTGATCTGTCTAAGCCTCAGCATCCTCACCTGTCCGGTGAGTGCTGGTTGTACCTGGCACTTGGTCATTGAGATGTTCAATTAGGAATGTTTGCAAAGAGCCCACTGTGGGGCCTGACACAGGGGCGCTCTGGGTAAGTAGAAGCCCGCAGTCTTTGGTCACTTGCATTTCCCAGAGGGGACTACCCCCTAGGGATGCTGCCTGGGGGTGGCTGGGCTCGGGGCCAGCTGGGGGTCTAGTCCGGGACCGCCAGCTGTTGGTTCCCGGCAGGCCTAGATTTGCCCCAGAGAATGTAATCTGGGGGATACAGGGTGGAAGGCAGAGCCGTGTGTTTCTACTGAAGCCGAGGCCGCACCGCGAGAGGCTCTCAGTGTGCCACTCCAGGGGCAGATGCTGTCAGCATGGAATTAGGGGATCCAGGGGGAGCCAGAACGGCAGCCAGGTCTGGGCCTGCAGACAAGCATACCACCGTTGTCTGAGAGTTGGCCCCTGTTCCGACACAGTCCAAATCCAGAGTAGCTGATCCCAGGCCGCTCACCAGTGAGCTTGTGTTTATCAGACGGTTTCTGTGCATTCACTGGGTTTCTGTGCATTCACTGAGTGTTAGGCATTGTACAGGGGACGAGGGCAAAGAGGTTACTCAGGTGTGGGCCCTTTTGAGAATGCCCCATCTGGAGGGAGGGAGACAATGTGTAACAGGTACAATTAGTGTGGTGAGTGCTATGAGCAAGGAGGGAGCAGGGGAGCCCCAGGCATGGCCCCAGTCCAACCTAGGCACTTGTGGAGAGGGTGGAAACAAGGAGGGCTTCCTGGAAGAGGTGACACAGAAACAGCATCTCAAGTAACTAGCCAGAAGTTGCCATTCAGAGGAGGGCGAGAGCGTGTCCCAGGCAGAGGAAAGCACCTTCTCAAAGGCTTAGGGTGGGAAGGGAGCGGGGGTTGTGCAGGGCGGCCGGGAGGCTGCCCCTCACCCAGGGCTCGAAGAAGGACAAGTCAGCTGGAGAGGCAGGTGGCAGGGGTCAGGGAGGACCTTCAGTCCCATGCTGAGAACTTTCAGCCTAACCCTTTGGGCACTGGGTGCAGGGGCACTGAAGAGTTTTTTTGCTTGTTTTGCTTGTTTTGTTTACAGTAGGAAGACACAGTCAGATTTATGCACTAGAAAGTTCCCTCTGCAGCTGGAGAAGGGCAGGTCTTCAAGTCAGACAGACCCAGGTTTCAGTTTCGCCTCTACCTGCCTCCCATGTCCTACTCAGTGACCACAGGCAAATCGCTCCACTTCTCTGAAGAGCTTCTGCTACATGGGGATAAAGCTACTTGCCCTGCAGGGCGATGTTGTAAAGGCTTCTCTGTCTCTGCCAGGCCTTGGCTTTGCAGGGTATGTTCCCGGCCCACAGGGGGCTCTCCATGGATCTGAGGAGACTGGCAGGGCAGGATCGGAATCGGCACCCTGGAGAAGCTGTCGTTGGAGACGGCCTTGGCGAGACAGTGTGTTGCAGCTCCAGCTCTGTCCGCTGGGTTCAGCCCCCTCACCTTACCTCAGTCACTAACCTCTGTGCGCTCAGCGTTCTCAGCTGTTAAGTGGACGTAACACAGGTTGAGCATCCTTTATCCAAAATGCTTGGGACCAGAAGTGTTTCCAGTGTTGGATGTTTTCACATTTGGGAACATTTGCAGATACATAATGAAGTAGCTTGTGGATGGACCCAAGTCTAAAGATGGAACGCATTTGTTTTATATACTCCTTGTACACATACCTGAAGGCAATTTTACATGGCATTTCAATAATTTTGTGCATAAAACAAAGTTTGTGTGAAGTACTTATGTGTAGAATTCTCCACTTGTGGCATCATGTCAATGCCCAAAAAGCTTTGGGTTTTGGAGCATTTCAGATTCTGGATTTTCGGATGAGGAATGCTCAGCCTGTGCCGTAGCATACCCCGTCCTGAGCTTGTCAGGGAATCCGTGAGGTAAGGAGTCTCTGGTGTGTGGTAGGCCTGGCGCACAGGCAGCCCTGATGAACGTGGGAGGCTGCACTGTTGTCATCATCATCTCTCCCACCAGCCCCGACCCTACAGCTGTTCTGCGCCTTCCCCCTGGGCACCACCTTCCCCGGGTTTCCTTCACCCCCCTTCAACGTTGGTGGGAGCTCGTGTTTGTTTTTCCCTGCATGGCTTGGACAGCTTGCGGAGTCGGGGTTGGGGAAGGCAGCCGCCTCCTCCCCCTGCCACCCCCAAGGCTCCAGGCTCTTTCTTGGCTCCATAACTTTCTATTGATGAGGCGAAGGGAGGAAAATCCCTTCCTCCCAAGTTGAGGGGGAAGGGCGCAGCAAGGTGTTTGTTCTTTTCTCCCTGCTCTGCCGTTCCCAGCTTGCCATCCCTTCCCATGTATTTAAGGGACATGGATGCAGAAAATGATGTTATTGATGAAGTCGCCATAGCAACGACCCTCAGGAGGCACACATTCCAGCTTTGTTATCCGACCGTGGCGGCAAGAAAGGCCCCACTCCTAAGTACAAACACGCTGGGCCGCACTGCCCTGCTTGAGATGCATCCGTGAACTTTGCATTGCAGAGGATGTGATGTACGCACTGGCTCGGGGCCAGGCAGACCATGCCATCGTTTCTCTCTGCGCACACTCTAGTGGAGTACCCAAGAATGATCGAAGGCCTTGGGGGAAGATAGGCCCCGGTGGGGAAGGGCTGCCAGGGCCTGTCAGAGTCCAGAGGAGATGGCGACCTGGGGGAGGGCCCATCGGGAGGAAGCACCGGCCACTTGGAGAAGAAGACACAGCCCGGGGCACGTCTTCCCCGACGCTGTCCCAACCTCCGTCTGCTTGCCTGGAAGGTGGGCACGGTGATGCCCGCTCATCAGGCTTGTTGTGAGGGTCCAAGTGAATGAAAGTATAGCCGGGGCCCAAGTTCATACATCACTTCTTCCAGAAAACTCAGAAGCAGCTCTTAAATGTGTCCAATCCAGCCCTCCTCCCAATCCCCATAACCACTGCCGTTCTACCAGGCTTTGTCCCTTTCAGAGTGATAGCAACAGCCTCTCCACTGTCCTGGCCTGCAGTCCTGGCCCTCCAGGGCATATTCCACACAGCCTCCAGAGATCTTTCTGACACACAAGCGTGTCGCTCCCCTATTGACAACTCCCCTCTGGCTTCCTTCTGGCCAGTACGAAGTCCCACAACAGCCTATCTGCACCCTTAGCCAGCACCTCACTCACCCAGAGACTGGGGCTGCACATTTAGCACACTCTGGGAAGCAGGCGCTACTACTGTCCAATTCTACGTAGGTGGAAACCGAGGTTCAGGGGTGAAGGGCTTGCCCAGGGTCACGCAGCAAGTGGCAGCCTGAATGTGGACCTGACACTGTGGCAGCAGAGCATCTGTCCTCTCCTTGCTCCCTGGCCCATCTTGGGCACCAAGGAGACACTTGGTCTGAGTTTGTAGCATGTAATTGGATTTGGGTGGTTGGATCAGATTAGATTCGACCTGGCGGGCCGCCTGGCCTGACGGGCATCAGGCCTCTGAAGACCAGGATTTCTGGGAATGACTCTGAAATTCTATCTCACTTCCCATTAAGAAGGGGAGACCAGCAGGGCTCTCTGCTGAACTTGCCTCTCCATGGTTCTCCCCATATCTAGGTCAAGGGAGCTGTCCTATGGCTCCCAAGAGCAGACGTGACACAAATCCGGGAGCCACAGGAGGACGGAGTTTGAACTGGGGCCCTTCCGTCCCTCAGGCTCACAGAAGCCTGCTCTGGGCCTGGGGCTTGGGGTTGGGCCTGAGTAGACTGGGCCCCTGCTCTGGAAGAGCTCACAGGCTGGCATCGGTGGACACAGCCTGCAGCTGCCACTGGCTGCATGGACCTGGCTGGCTCAGGGGAGCTGGAGGAGGCCCGGGGGGTCCTTCCAAGCTCACAGCAGAGGGGGTAGAGTCACAGACCCACAGAGTCCTTTCCCATCTGGAGCCCAGGCCCATCCCTAGAGCAGAAGGGCTTGGAACCCAGCACCTCACGTGCCTCAGGGTTCACCTTTTCCCCTTCAAATCTCAACTTAGCCCTCATGGCCCCAGCTGCCACCCAGAGATACCACCTGCAGGAGGGGATGAGTTGGCATTCCTTCCCGTTAGCTCACTGCCCTCAGATGGCCCCTCTGGGAGAGGGCAGAGAGGGCATGCCACCCGCTCTCCCTCTGAGGTTCGGAGGCACAGAGGATACCGCAGGTGCTCCAGTGGGTGGGGCCAGTGCCTTATCCCTGCCCCAGCCTGCCACCCTGGTCGCTGTGTCACTGTTGCTTTATCTGTCTGGTGAGGAGCTAGAATGGGCCACCCTTAGACCCTGCTAGTGCTGGGGTCTCTTCCTGTCCAGCATGCTGTGTTAAGTGAGGGGGAAGGGACTGTTCCACAGGGACCGCAGGACTTCTCAGAGCCTTTATCATGTGCTGCGAATTTCCCACATCAGGCATCCGAAGCGCTGTGTTTCTAGCACACGCAGCTAGGGATGCCATAAGAGCATTTTCAAAATTCTAGCCTTGCCTCCTAAAATAACAGACAACCCGCTTCATCTGTTCCGAAATAGGGGGCTTTCTTTCTCTCTTCTTCCTTCCTTGCTCCCTCCTCTCTCCCTTTCCATTCTCCCCTCTCTTTCCCCACTCATTCTTCCCTTTCCTTCTTTCACCCACTGTTTGCAGATCCCTAACCCTGTGCCAGGCCCTGTGCTGGGTACTCGTGATACTGAAAAGAATGAAGCTCATGTCTCCCCAACGGGTTACCCACGGTTGGCAGGAAAGAGTGTGACGGAAGCAACTATTCCGATTTCCTACGAGGCAGAATGAAGCAAGGGCAGATAGGAGTGCTGTCGTAGCAGCCTTGCTCTACCAAGACCCTCCCTGTGTCTCCCTCGATATTGTCACCTCGTTTCAGCTTCCCAGCAACTCTCAGGGGCAAAGATTATTACATCCCCATTTCACAGCCGAGAAAACAGACATCCTGTGCTGCAGGGGAGCGGAGGCTTTGTCCTCACACTCAGGGCCTGCCAGTAACAGCCGTGGAAGGTCAAAAGAGGAGCCAGGGTATGTGCTTCGTGGAGGGGCTGCTCCGAGAGCTTCAGGGGACGTAGCATCTGAACTGGCCTTGGATTTCGCTGGGCTCTTACGTCTGGAAACAGTGGCCAGTAACAGGCACCGTGTAGTCGCCCACTCTGCACCAGGTTCCCAAATCGGTTCCCCCCAGGAAACGTCTGCTCCCTATTAGCCATCTGGGTCCCACAGGTGTAGCCGAGTGACCCCAAGGTAGGAGAACTTAGGCTGGGAGCCCAGTGGCCCAGCTTCCAGCCCTGCTGTATGTGCTGGGACATTGATTTCCCATCTCAGGGGCTCATTTTCTGTCTCTATAAGATAGACAGACAAGATGCGCTGCAGGGAGGGGTCCAACCCTGACCTTCTGTGGTTCCGCCAGCCACGGAGCCTATCTGCTTGTGGCCTCCAAAAGCCAGTGTTGCCCGTGAGTGGAGGTGAAAGCAATGCAGCTGACAGAGGAGCTGATGAGTGCTTCGGAAGCCACAGTCAGCCCCCAGGCCAGGCAGTAGCAGCCATCCTTGCAGTGGTTGTAGGGTCATTTTGAAATGTGATAGTGATGCTCCCCCAACCACCCTTCTCGGGGAGGAGGCGCCTCAGAAGCACTCAAGCTGAGCAGACTCCAGCCTGACCACAGCCTCACCATGCAGCGGGTGAGCCTGGCTCGCGCGGGCCTGACTGGGGCATCTCAGGGCACCCTCCTTGTTCTGGAAAATATAGCTTTTAATACAAATATATGACTTGTGCTAACATGTAATATTTTTTTTTTCTTTGAGATGGAGTCTCACTCTGTCGCCCTGGCTGCAGTGCAATGGCGCAATCTCAGCTCACTGCAGCCTCCACCTCCTGAGTTCAAGCAATTCTTCTGCCTCAGCCTCCCAAGTAACTGGGATTACAGGCTTGCACCACTACACCTGGCTAATGTTTGTATTTTTAGTAGAGACGGGGTTTTACCACGTTGGCCAGGCTAGTCTCGAGCTCCTGACCTCAGGTGATTCCCCCCGCCTCGCTCTCCCAAAGTGCTGGGATTACAGGCGTGAGCCACCATGCCCACCCCCATGTAACAAGTTTTTTATCTTGTTTTTAAATAAGTTAATAAGTAAATGTAAATTTCTCTCTGTAGTATCTAGCCAGTCTCGATAGCTGTAACACATAAACACGTCCATCAGAGCGATTTGGGCTCCTTTATAATTGTCAGGAATGTAAAGAGGTCCTGAAGCCAGTCCCACTAACAATCACTGGCCCGTCCCTTGCTCTCCGTTGCAGAGCCAGTGGGGGCTCCCGTGCTGGGGATGCTGGGTGAGAGGCAGCGTGCAGGGGGCCTACCGTGGGGTGTTGAGTGAGGATGGCTAATCACAGGACCTCAGTTCTACCTCAGGGTCTTTAGGTGGGAGACGAAGGGCTCCACCCTCTTCCCCAAGTTGTTGAGAGGTAAAGTAGAGACCTTTGAGACCAGCTGACTACAGATAGGGCCTGGGGCTCACCCTTCCCAGCTCTGCGATTCTGTTGCTTAGTGTCTTATTGACTGTGGGTTACTGCAGTCCATAGTCATGCTAGAGTACGTCCCCAAAGTGTCCTTCACCAAGAAAACAACAACATCTTGGCTCAGTGTTAAAGTCTTTAGAGTCTCAAGAAGAAAGATCACTTGATGGCAAGTCCACGACGAGGGAGAAAACTGAAAGACCTCTAGGGCTTAATATTCCATTACCCAGGGCTCCGGCGTGCATCAGCTCCCCAGTGACAAATGTATGGTTGGTGATGATTAGCAAGGCTTCTTGTAAACTGTGATTCTTTGGCTGGGAATGGAAATTCAATCTCCCTTTCTTCATCATCTATAAGCCTTTGCCAAACAAGGGCCCTTGGGCTCTTCCCAGCTCAGGAAGAAAGCACAGATCTGCTTACAGCATTGATCTCCTGTGCCGGCCATAGGACAGCCCTAGGAAATTCACATGGGTGGTGGCATGGGGAGACACAGGGAGTAGAAGGCAGGAGCCAGGAGGCTTTGGGGAACTGGTGGAGTTTGAGGCAGGCCTAGGATTTAGTTTATGGAAGATAGGAGAGGGTGTCCGGCCCAGGAGGAAGGAGCAGCAAGGGGAGATGGAGCACCCTCGGGGGCTGCCCAGCAGGCATTGTGGGATGGCGAACCGTGGAGTGTGTACAGCTGTGAAGAAGCTGGAACAGCAGGGAGCCATGGAAGCCAAATGAACAGGGATGAAGGGGGCGACCCTGGACTCAGCCCACCGCCGACAACAGCTGTCAGTAACGGTCAGGGAGATGGCTTGCTGGCCACCACCCACTGGCCAAACCCTTACCAGGGCAGGAGGCTCCCAGAGGACCTGATGAGGGACTGAATATGTCTCAGTAGCCTGGGAAGGTTTCTCTACCGAGAGCCGCCTCTGGCCACCCGGTCCAGCCAGGCCCCAGGGAGGAGCCACGCTGTCTCCAGACCTGCAGGAGAGACACCGGCCTCAAGAGCCAGTGCCCCCACAGACAGACCTCGTCTCTTATTGCCTGGCATTTCCTGTCTGTAACTGGATTTAATTTGCACAGCTCCTCTGTGAGACAGAGGTGATCCTGCCCCTTCTAAGATTAGGCTCAGAAAAGGGAAGCAGTTGTCTCCCAGGCCACAGCCAGGAAGGAAGCCAGATTCACACCTACATCTGCCTGACTTTACAACGACCTTTCTAAGAAAGGGACGTGCTATGGCTGGCTTGTCTCAGCTTGTGAGAGCCAACTGTGCACATTTGTTCCCAGCTCTACCCTTGGCGACATCTCCCTGGTACCTTGAAATTAGCCGTGGCTGGCGTATTTATCCCACGTAAATTGGTAAATACTGCAAATCAGCCTCCACCCCTGCCGGCTGTTAAGCGTTGACCGCACGCCACTATCTGTGTGACTCAGGCGCTGATGCTGTTTTGGAATCGAGCCAGCGGAAAGGGTCTTTCCGTGTGAACTTGCAGCTTCTGTGCAGGGCAGCAGCATGAAAGCGCTTTCCGTGCTAACTCGTTGCTTAGTTAGACTCTGCGTCATTCCAACAATTTGATTGATTAGTGAGAAAATCAAGGTGAGGAAATATGAGTCGCAAAATCAGGTGAAACCAGGAGTTACAGTGCCGGGCAAAATGCAGGCTTCCTCATTTCCATTTGTTTGTTTGATTTTTAACTTTAGACGTTTTTGTCTTTATTACAACTAGCAGGGTGTTTGTGTTCTTAAATCTATTCTGTGTTGCTGCATACCCGTATTTAAAGTGGACGGGGTCAGGATTGAGCCAGTCCTCCCTTGGAACAAGAGGCCGGTGTGTCCCGGGGGAAGGAGGTTGCCCTGTGCGTGTTCGCCGTCTGCAGCCTTCACTGCCGCTCCCCGAGCCGGCTTCACTCCTGCCTGAGCTTCCTGTGGGTGGAGGTGGAAGGCAGGTCACAGAGCTGGTGGGTTGGCAGACAGAGGCGCTTCCCTTTCATCTGCCTTGGCCTCTTGATGGACTTGTGACCTACAACCTCTCACTTGACCCCTGACCTCATAAATTCTAGAAACGCCTCACAAATCACCAGGAAGATAAACATCAACTGAGGTCAACGGAAGGGGGTATGAGCCACTCCAGGCAGACAGAGAGGGGAGATCCAGTCTGCTGGGCGGGTGGGGGGTACCCTAGAACCATGGGTGGCTCGGGAGAGGGGAGCAAATCACCCTGACACAAAAGTAGTTCTACAGACCATGCCCCACAATCTGACCTAGAGCAAGAGCTTGGTCTCCGTGGGTCACGAGGTGCCATTTACAGTGCAACTCACAGAGCAAAGCCTGAATCTAGACCCAGGCACCGTGCCCTTGCTTTCTCCCTAAGGGATATCCATGTAGATGGCTGCTGCACACACGCATATGTGTGTGTGCGCAAGTGCGTGTGTGTGCATGATACATGCAATGACAGCCCATTTGATTGTTACATATCATTGGCTATCCCCTTTCAGCCTGAAATTTTCTCTCTCCCTCTCTGCCTGGTCTTCAACCCGTCTCTTGTCTGTCTCTCTTCCCAG
Seq C2 exon
AGGGTATGAACTGCATGAACAAAGACCATGGCTGTGCCCACATCTGCCGGGAGACGCCCAAAGGTGGGGTGGCCTGCGACTGCAGGCCCGGCTTTGACCTTGCCCAAAACCAGAAGGACTGCACAC
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000159307-SCUBE1:NM_173050:4
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF146701=FXa_inhibition=WD(100=78.3)
A:
NA
C2:
PF146701=FXa_inhibition=WD(100=86.0)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)