HsaINT0146235 @ hg38
Intron Retention
Gene
ENSG00000146197 | SCUBE3
Description
signal peptide, CUB domain and EGF like domain containing 3 [Source:HGNC Symbol;Acc:HGNC:13655]
Coordinates
chr6:35239752-35240490:+
Coord C1 exon
chr6:35239752-35239874
Coord A exon
chr6:35239875-35240373
Coord C2 exon
chr6:35240374-35240490
Length
499 bp
Sequences
Splice sites
5' ss Seq
AGGGTGAGC
5' ss Score
7.75
3' ss Seq
TTGAATCTTTGCTCTTCCAGATA
3' ss Score
10.31
Exon sequences
Seq C1 exon
ATATAGATGAGTGCCGCTTAAACAACGGGGGCTGTGACCATATTTGCCGCAACACAGTGGGCAGCTTCGAATGCAGTTGCAAGAAAGGCTATAAGCTTCTCATCAATGAGAGGAACTGCCAGG
Seq A exon
GTGAGCAGACTCAGCCAAAGGTGAAAGCCTTAGGAGAGGTTCTTGTGGGAGAGCTTCAAGGAGGCCAGAGGGCTAAAGTCTTAGAAACTCAATAGATATCACACAGAGTCTCTAGAGGCAGTGTCATCCTGCAAATTAGCAAATGGTACTCTTTCCCCTCAGCGGACTAGCTCCATATCAAAGCATTCAGCCTGGCAAGGACTGAGGGATGGATTTCACCCCAATTCATATCCTTGGCAGAGTAGGACGTACCTAACCACACATGGTGGGCCCTGACCTAAAGGCACCAGATCTTGCAGTTCCTAATTCCAAGGACTTCAAATAGAGGGGGCAGAGAAGATGGAATGGCATTGTTAAATCACTGGTCCTAGAGCTAGGACATGAATAGGAACTCTTCAGTTCAAGGGGGAAAGCCAAGGCCCCTCACTTGGGTCCTTCACCTGAGCAAGGGTCAAGTGCTCCAAGACAGATTCAGTGGCTTGAATCTTTGCTCTTCCAG
Seq C2 exon
ATATAGACGAGTGTTCCTTTGATCGAACCTGTGACCACATATGTGTCAACACACCAGGAAGCTTCCAGTGTCTCTGCCATCGTGGCTACCTGTTGTATGGTATCACCCACTGTGGGG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000146197:ENST00000274938:8
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF146701=FXa_inhibition=WD(100=85.7),PF0764510=EGF_CA=PU(0.1=0.0)
A:
NA
C2:
PF0764510=EGF_CA=WD(100=95.0)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GATGAGTGCCGCTTAAACAACG
R:
CAGTGGGTGATACCATACAACAGG
Band lengths:
230-729
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development