HsaINT0147501 @ hg38
Intron Retention
Gene
ENSG00000143434 | SEMA6C
Description
semaphorin 6C [Source:HGNC Symbol;Acc:HGNC:10740]
Coordinates
chr1:151138316-151138731:-
Coord C1 exon
chr1:151138630-151138731
Coord A exon
chr1:151138407-151138629
Coord C2 exon
chr1:151138316-151138406
Length
223 bp
Sequences
Splice sites
5' ss Seq
GGGGTACAA
5' ss Score
-0.67
3' ss Seq
TCTGCTCCCTCTGCCCTCAGATA
3' ss Score
12.6
Exon sequences
Seq C1 exon
GATGAGTGCTACAACTATATTCGTGTTCTTGTTCCCTGGGACTCCCAGACGCTCCTTGCCTGTGGAACGAACTCATTCAGCCCTGTGTGCCGCAGCTATGGG
Seq A exon
GTACAAAAGAGAGGGTGGGGGTTAGGATGGGAGTTGGGGGGACCCCAAGATGGGCAATGGGTTTGATGGGAAAGGACCAAGGACTGCGGTTGGGGAATGGGAGTGCCCAGAATGCAAGGGTCCAGAGGGGTTGGGGAGGAGGCAACGGGACAGGAGGGAATAGGCTATGGAGCCAGACTCCAAGACCCTAAAGGTTCCAGGCATCTGCTCCCTCTGCCCTCAG
Seq C2 exon
ATAACTTCGCTGCAGCAGGAGGGTGAGGAACTGAGTGGGCAGGCTCGATGCCCCTTTGATGCCACCCAGTCCAACGTGGCCATCTTTGCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000143434:ENST00000368914:7
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.028
Domain overlap (PFAM):
C1:
PF0140314=Sema=FE(27.5=100)
A:
NA
C2:
PF0140314=Sema=FE(25.0=100),PF0140314=Sema=PU(1.1=9.7)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TGAGTGCTACAACTATATTCGTGT
R:
GCAAAGATGGCCACGTTGGA
Band lengths:
189-412
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development