HsaINT0154535 @ hg38
Intron Retention
Gene
ENSG00000145147 | SLIT2
Description
slit guidance ligand 2 [Source:HGNC Symbol;Acc:HGNC:11086]
Coordinates
chr4:20488819-20491899:+
Coord C1 exon
chr4:20488819-20488982
Coord A exon
chr4:20488983-20491760
Coord C2 exon
chr4:20491761-20491899
Length
2778 bp
Sequences
Splice sites
5' ss Seq
GTGGTAAGG
5' ss Score
8.37
3' ss Seq
CCTGTTTATTTCTTTTTTAGGTC
3' ss Score
12.98
Exon sequences
Seq C1 exon
TCGACTGCATTCAAACAACCTGTATTGTGACTGCCACCTGGCCTGGCTCTCCGACTGGCTTCGCCAAAGGCCTCGGGTTGGTCTGTACACTCAGTGTATGGGCCCCTCCCACCTGAGAGGCCATAATGTAGCCGAGGTTCAAAAACGAGAATTTGTCTGCAGTG
Seq A exon
GTAAGGGAGAAGGAAGAGTGATGTTATTGTGTTTATTGTATCCTGTTATGTAACAGAATGTGAGGGCTGCATGCGTCAAAGGTTTCAGTATTGTTCACTAATGTTCAATTGTGCACTAATCACTCTACAGAGATCCTCTTTTTCAGTGAAAATATGTTCTGAGACCTCACTATATCGGTTGGCAAGTACTGGTTACTTGTATCTAAATTATGATAAAACACTTTTCAGTTTTCACTCCAGGGGAAAATATGGAAAATCGCTAAATGATGATTCTACTTTTGATTTTTTATTTTCCCATTAAGTAACAATTTATAGCTACTTTTATGTTAACAATTGAAAAAAAATGATTAGCTAATCCTGGATCCCTGCTATGAAATTCAAAGAGCAATTCAGCCATAGTTGCAAAGTAACAAAATACTTTTCATGCATACATGTATACTAATGGTTCAGTTTTACTTAAAACAAATATTAAATGACCAGCTTTAATAACAAACATCTAAAAACAAAAATAAGACATAGGGTCAGGCACTGTGGCCCACGCCTGTAATCCCAGCATTTTGGGAGGCAGAGGTGGGCAGATCTCCAGAGGTCAAGAGTTCCAGACCAGCCTGACCAACATGGCAAAACCCCGTCCTTTCTAAAAATACAAAAACTAGCTGGGCATGGTGGTGCATGCCTGTAATTCTAGCTACTTGGGAGGCTGAGGCAGGAGAATCACTTGAATCTGGGAGGCGGAGATTGCAGTGAGCTGAGATCACACCAGTGCACTCCAGCATGGGTGACAAGAGAGAAACTCCATTTCAAAAAATAAAAATAAAAAATAGGCCGGGGTGTGGTGGCTCACGCCTGTAATCCCAGCACTTTGGGAGGCTGAGGCGGGCGGATCACAAGGTCAGGAGATTGAGACCATCCTGGGTAACATGGTGAAACCCTGTCTCTATTAAAAATACAAAAAATTAGCCAGGCATGGTGGTGGGCGCCTGTAGTCCCAGCTACTCGGGAGGCTGAGGCAGGAGAATGGCGTGAACCCCGGAGGTGGAGCTTGCAGTGAGCCGAGATCGCGCCATTGCGCTCCAGCCTGGGCAACAGAGTGAGACTCTGTCTCAAAAAATAAATAAATCAATAAAATAAATAAATAAATAAATAAGACATAGGCTGTGTCTAATATCAATCAATAGCTAACGTTTACTGAGTTTTTTAATATGCTTAAGCACCAACCTAAGTATTTCACATATATTTACCTCACTTCACCTCCCTTATAACAACTGTATGAGAAATGTAATATTATCTCTATATTTGGAGATTCAAATGCTGTGAAAAAGAATATCCTTGCCAAAGTTTATGTAGTTGAGTCCAGGGATCTCAATAGAAGTGGTTTGATTACATATATACACACACACGTGCATGCACACACACACCCCCATACATAGTATCTTATTTGTATATGTGTATATATATGTGTGGGTGTGTGTGTATATATATATATGTATGGTTGGTTCTGCTTCAGCTTCAGAAGTATCTGTTCAAAATACAACAAAACAAAATTTTAAGAAACGTATAATGCATCGTAAGTAGTTCACAGATTTTTAAAGGCAGGGTAGGGAGACATGACTAGTACTTGATGCTATTAAATGGTTATATTTTAGACCCTTGTTTGTGTTTTTTCACATGTTTTATAACCTAAGAAAAATTTTTGTATAATATCATGGAATGTTCTCAATATGTCTGATTGCTTTTTTAAAAAATTAAATAATGAAATGACTAACAGTTCGTTACTAACCACTTTTTTCTCTCTTCACTTTTTCCTTTCTGTTTTCTAGATGAGGAAGAAGGCAAGTTCACATTTCTTTTTTAGACCGAGGATATTTTTGTAGTTTAAGAGCTTGTTTAGAGGGATAGAATTAGCAGCTGGCTTGCAGCCTCTTCCTGGCACGTCACCACCACTAGGGCCCTTTCCTGGCAGGTTGGAAAGGGCAGTCCCCACTGTCTTCCAGAAACCATGCATGTCCAGATGCTTATTTAATACAACTGTGCTGATATTCTGTTGCTCACCTTTCAACCATTAATGTCTCATTTAAAAATTGTTCCAAATATTGAGTAATAAAAGTACACACAGGAAGGGAGCTACTTATACCAAAATTTAAAATTACCCAAAGCCCCCAAAAGAATAATTTTTTATTAACAATAAGATGACTTTATACAAATTATTATTATGATTTCAGATAAATTGATAATTTTGAACCTATCAAGACATCAAATTCTGGCTTATCTAATTTTTCCCCACATTTATTGGCATATGATTATTTAATTTGAGCAACAATTATCTTCTGATGGAAGTACTACTGTTTTGTTTTCTTTTTTAAAAGAAATTACAAAGTAAATAAAGCTGCATGAATTTGATAAAGACCAAGCTCTATTTAATCTTATTAGGAATGAAGATAAATTAGTCTGAAGTTGCTGGGCTTTTGGAAATTAGAATAGTTTTGAATGTAATTCTGATTTTAAAACTGAATTTAGCTTTTCTCACAAGTTTTAAAAATTAGCAGTCTTATGACCAGTTTTTAGAATCTCATTTACTTCCTCTCATTTGCTTTATTGACCTGAATATATAAATGCATGCCTCCTAAAATATATTTTAGAAATATAGGACCATTTTATCATCATGTATTTAAAGAGATTTATTTATGTGAAATGCTTTGTTACTTGAGCTAAGTTTGTCTGTTTCACAATTATGATATTCAGGAGGAAAAATATAATTCCTGTTTATTTCTTTTTTAG
Seq C2 exon
GTCACCAGTCATTTATGGCTCCTTCTTGTAGTGTTTTGCACTGCCCTGCCGCCTGTACCTGTAGCAACAATATCGTAGACTGTCGTGGGAAAGGTCTCACTGAGATCCCCACAAATCTTCCAGAGACCATCACAGAAAT
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000145147:ENST00000504154:8
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.006
Domain overlap (PFAM):
C1:
PF138551=LRR_8=PD(11.5=12.5),PF0146319=LRRCT=WD(100=44.6)
A:
NA
C2:
PF0146213=LRRNT=WD(100=59.6),PF138551=LRR_8=PU(8.2=10.6)
Main Inclusion Isoform:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains