HsaEX0060157 @ hg38
Exon Skipping
Gene
ENSG00000145147 | SLIT2
Description
slit guidance ligand 2 [Source:HGNC Symbol;Acc:HGNC:11086]
Coordinates
chr4:20488819-20491899:+
Coord C1 exon
chr4:20488819-20488982
Coord A exon
chr4:20490803-20490814
Coord C2 exon
chr4:20491761-20491899
Length
12 bp
Sequences
Splice sites
3' ss Seq
TTTTCCTTTCTGTTTTCTAGATG
3' ss Score
12.19
5' ss Seq
AAGGCAAGT
5' ss Score
3.24
Exon sequences
Seq C1 exon
TCGACTGCATTCAAACAACCTGTATTGTGACTGCCACCTGGCCTGGCTCTCCGACTGGCTTCGCCAAAGGCCTCGGGTTGGTCTGTACACTCAGTGTATGGGCCCCTCCCACCTGAGAGGCCATAATGTAGCCGAGGTTCAAAAACGAGAATTTGTCTGCAGTG
Seq A exon
ATGAGGAAGAAG
Seq C2 exon
GTCACCAGTCATTTATGGCTCCTTCTTGTAGTGTTTTGCACTGCCCTGCCGCCTGTACCTGTAGCAACAATATCGTAGACTGTCGTGGGAAAGGTCTCACTGAGATCCCCACAAATCTTCCAGAGACCATCACAGAAAT
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000145147_CASSETTE2
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (No Ref)
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.006
Domain overlap (PFAM):
C1:
PF138551=LRR_8=PD(11.5=12.5),PF0146319=LRRCT=WD(100=44.6)
A:
NO
C2:
PF0146213=LRRNT=WD(100=59.6),PF138551=LRR_8=PU(8.2=10.6)
Associated events
Other assemblies
Conservation
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
AGCCGAGGTTCAAAAACGAGA
R:
TTGTTGCTACAGGTACAGGCG
Band lengths:
105-117
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- The Cancer Genome Atlas (TCGA)
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development