HsaINT0156843 @ hg19
Intron Retention
Gene
ENSG00000137642 | SORL1
Description
sortilin-related receptor, L(DLR class) A repeats containing [Source:HGNC Symbol;Acc:11185]
Coordinates
chr11:121478813-121481867:+
Coord C1 exon
chr11:121478813-121478885
Coord A exon
chr11:121478886-121481784
Coord C2 exon
chr11:121481785-121481867
Length
2899 bp
Sequences
Splice sites
5' ss Seq
AAGGTAAAT
5' ss Score
8.88
3' ss Seq
GAATTCCTTTTTGTTTTCAGTGA
3' ss Score
7.54
Exon sequences
Seq C1 exon
GTGGCTGCGGTGACTAGTCGTGGAATAGGAAACTGGAGCGATTCTAAATCCATTACCACCATAAAAGGAAAAG
Seq A exon
GTAAATGATCCCAGCATTTGCAGATTTAGAGAAAATATTATACAAACCCTTTCAAATGACTTTCAGTATGACCGGAAAATGGAGAAACGTAGTTTAGAAAAACATCACACAACTTTCTTCTCCCCAACACACGCACATTTTTGGGTGTCTCTGTAGTGCTTTAGATAGAGTCTTTTTGGGGTGACTGAGTGTCTTTTTCCTCCTAGTATTGAGCATTTCTTCTAATGCAGACATACAAAGGGATTTCCAAAGGCCATCATGCGCAGCCCTTTGTGAGTAGTCAAAATATCTAAAATAGAAGGAGTCCTTCCTTCTCACCAAAGCTGAAGATGATTTTGTGCATGTTCACTTACGGGGTTTTAAAGAAAGCACCATGCTGACTCTTGTTATTCTCCCAGTGGCACTGGCAAACTGTGTGTAGGTGGTTTTTTATCTTGTACTAGAGCTGATATTAGTAATAACTGATGGCTTGCCAAGGGCAGGACACTCTAGAGTGTTCACTGCTTTGCGTACATCAGCTCATCTAATTGAACAGTCAGAACAACTACAAGAAAGGATAAGGAACTGGAATGAGGTTATGTCACTTGTCCCAGGCCACACAATCAGTAAGTGACAGAGCTGGCCCTGGAACCTGATCTGCCTGACTCCAAAGCCTGTGCTCTTAACCACTGTGCTCCACGCTTCTCTCTGGGCTGAGACACATGCGGCCTACTGGACCGCCCTGCTTGCCGGGGGTGGCGGGCTCAGCATCTTGCACGAGTGCCTCATGAGGGCAGAGATCTGGTCTGTTTTTCTCTACTCTATCACGGGCATCTAGTAGAGACTAAGGAAATAATTGATGATTGAGTGAATCGAAGCAGTTAAATGAAGGGTTCTGGCATACTTTGGGAGATGGACTACAACTCATTTTCCAGAGTGGTTTTCCTGACCTTAGCCTTGACACTGGGGACTTGCATTTCTGGACTTCCAGGTATTAAAACCAGATGGACACTGTGGCATGCAATAGGACTGGAAGATTTTACTTTAACCTAAGCCTGTGAGGAATAGGCTCTGGGTCATGGAGAGTCACTATCTAGTCCCCTCTAAAATCTGGAGCCTTTGAGATCAGGGCCCAAGGCGGCCAAACGTAGTGCCACCAGATGGTCTTTGGAGCTGAATGCTTGCAGGTATTAGAGAAAGCCTGCTGAATTCACACTCTCCTAGAATTTTTATTGTTGTATCTCTTCTCTCTACAAAGTCTGTTTCAAAACACTGACCACACATACCAAGAAGGGATGTTGGAAGAGCAACCAAATACATGTACCTTGAATTCCGAAGGCACAAGTCACAACTGCATTTGAAAATCTCAGTGGATGGTTGGTTCTCTTTAACTTCTTTTCTGTGATTTTGATGAATCTCAGCTGCTTGCATATATTTGGGCTAGGATTTGTACAGAAGGCAGCTGTGTGCCACATCCAAAAAGTGTTTGTTGTAAAATATCTGTGACATAGTATCATAATAACGTTTTAAGATAAAGGACAAAGACAGCAGAGGCATCAGCCAGACGCGCCAGGTTAATTGGTGAATGTAGTGGATTAGTAATGACAATGAGAAAAGCCACCATTCCCTGAGCACTTCTTATACACTAAGCACCATGCTATTGTTGCTCGTGAATGGATCCCTTATTAATCCTTATGAATCCTATGAGATAAGTATCCTTATCCTCATTGTGTAGCTGAGGAAATGGGTTTGGAGTGGATTGTGACTTGTCCCTGGTTGCCATGATTATAATTCAAGTCAGCTTTACCATATGCAGCACTCGCACTGTTTTGCTCTGTGTTGGCCGCCTGAAGCTTCCAATATCCTTTCTTCTTCCGGTTATTGCATTTTCCTGAAGCCTAGTTTTATTACATGATTGATCATCTGGACAGACCTCTTCAGACTTTGACACATCTCTTTTGCCACCAAATCTTATCTGCTCCTTTGAGTCTCTCTTGCCCAGTCTATAGAAGGGGCATATGTGTGGAGAGTCTAATATGCAAGTTGTTGTTTAAATAATATTTTCTGATAATATTGATCCATTGAGCTCTTTTAGATCATGCTGGGCCAAGCACTGTCAGCCATCTGGTGGGAAGACCTTCCAGATGACAAGCATGGCGCTCATTGGTTGAACTGAGAGGGGTCTTTTCCTTGGCCACTTCTCCTTGCCCCCTCGACTCTTAGCTTGAGCTCCAGTCTTTTTGAGAGCACCAGTGGTTTCTAGTTGTTTAGTTGGCCATATGTGACGCTATATTGGAAAGGAAGAGAAAGAGAGTATCAGTTGAGTGCTAGGCATCACACATACATTATTTTAGTTAACCTTCCCAGCTCTGTGAAATGCAGATAACATCTCTAGGCTCCAGGAAGATCAGTAACTTGCCTAGGTTACACAGATGCCAGAACAGGAATTCGAACTCAAGTTTGCCAGCTTCCAGAGGCCACATTCTTTCCATTTTGCCACACGCACGTTTACCATTTACGATTTACTCCATTGTCAGCCTTCCGAAAGGACTTGAGATTGGTGGGACTTTGTTAGTGCCAATCAAGATGCCACTCGCAGTGAATGATCCCTGTTCCTTTAAGAACCAGGCTGAAGCTGGGCTGTTTTGGGACCTTTACAAAATGGAACTTTTCTGCCTGACCTAATTGCCAGGATAGCCGACTGAGCCAAGATAGTTTTGTGTTCACCAAGCAACTGTGGACCAACCTTAGCTTCAGGAAAACAGTGGTAAAAAAAGATCGATGAGGAACACTGCCAAAGAAATACCCTTTCTTCCCCGACTGAAAGATGGCTTTGTCCGTTGAGTTGAAAACTATTAAGTCCTGCCTTCCTCACTTTTCATCACGTGGCTTCTGTTTTTGAATTCCTTTTTGTTTTCAG
Seq C2 exon
TGATCCCACCACCAGATATCCACATTGACAGCTATGGTGAAAATTATCTAAGCTTCACCCTGACCATGGAGAGTGATATCAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000137642-SORL1:NM_003105:38
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0004116=fn3=PD(14.3=48.0)
A:
NA
C2:
NO
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)