HsaINT0169662 @ hg19
Intron Retention
Gene
ENSG00000186452 | TMPRSS12
Description
transmembrane (C-terminal) protease, serine 12 [Source:HGNC Symbol;Acc:28779]
Coordinates
chr12:51279029-51281663:+
Coord C1 exon
chr12:51279029-51279171
Coord A exon
chr12:51279172-51281044
Coord C2 exon
chr12:51281045-51281663
Length
1873 bp
Sequences
Splice sites
5' ss Seq
AGGGTAAGA
5' ss Score
9.21
3' ss Seq
TTTTGGGACTTTTTTGACAGGGT
3' ss Score
5.7
Exon sequences
Seq C1 exon
GTAACGCTACAAATATTTTACAAGATGCAGAAGTGCATTATATTTCTCGAGAGATGTGTAATTCTGAGAGGAGTTATGGGGGAATAATTCCTAACACTTCATTTTGTGCAGGTGATGAAGATGGAGCTTTTGATACTTGCAGG
Seq A exon
GTAAGACCAAGTAATTTTCCTTTAAAATATTTTCTGAAGCCAGAAGGGAACTTGTCAAACAAGGCCTTTGATAACTTTCTGGTGGTCTTAATTATCAGGCCTAAAAATAATAAATCATTTTTTCTCCTTTTTAACTATTTCAACAATCCAAATCTTCTTGGTTCCTGATTCCATGGTTTCTGCTGTCATCAGTAGGCAGAATTTACCTTGAATTCTTTTTTTTAATCATTACCTTTGAGATATAATTCACCTAGTTAAAAGTGTACAGCTCAATTTTTTTTTTATTTGAGATAGTCTCGCTTTGTCACCCATGCTGGAGTGCAGTGACACAATCTCTGTTCACTGCAACCTCTGCCTCCCAGGTTCAAGCGATTCTCATCCCTCAGCCTCCTAGGTAGCTGGAATTACAGGCACACATCACTATGCCCGGCCATTCTTTTTTTTTTTTTTTGTATTTTCAGTAGAGACAGGGCTTCACCTTGTTGACCAGGCTGGTCTTGAACTCCTGACCTCAAGTGATCTGCCCACCTTGGCCTCCCAAAGTGCTGGGATTACAGGGGTGAGCCACTGCGCCCAGCCTGTTACTGTCTTTTTTATTATAACCATCCTTGTGGGTGCGCAGTGGTATCTCATAGTGGTTTTAATTTGCATTTCCTTAATGACTAATGATGTTGAGCATTTTTGCATGTATTTATTAGCCATTTATATATCTTCTTTACAGAATGTCTATTTGGATCCCTTCCTCATTTTTAAATTGAGTTGTCTTTTTATCACTGAGTTATAAGCATTTTTCATATATTCTGGATACAAGTCCCTTACCAGATACATAATGTACAAAATTTTTCTCCCATTCTGTAGACTGTTTTTTCACTTTTCTGAGGTTATCATTTGCAGCACAAATGTTAATTTTTTTAATGAAGTACAATTGATCCATTTTTTGTTTTGTCTCATGCTTTTTTACTCTTCCTTTATTCCTCTTTTCTTCACTATTTCCAAAGCTACTAGTCCTTCACTCCTGAGTAACCCATGCTCTCACCTTTTCCTACTCATTCTCATTTCTGCAATCTAAAGTTTATCTTTTCTGTGTCCTTTTCCTTAAAAATCTTGCTGAATGAAATAGTAAAGAATCCAATCTAAGTGAATTGCATTCCTAGGCCAAACATCCTCATCATCAAAAAATAATTATTCAATGCCTGCCTTATATAGAGAATCGGAAACAGTTATCTCAGTGTCCTTGTTGTTTTCAGTGCATTAACAGGCCTTAGTAACAGCATTTGGGTGCATTCCTAATTTTGTATAGACTATGAAAGTGACCTGTCATTTATAATACTACTGAGAGGCTTTGCCATTTATGCTCATTTTCCTGCACTAGCTATTGTCAACACTTAGAAACTTGTCTTCTATTGCAAGATGCCAGTTTACTCCTCTCCCTGGCAAGCAAACCACACACGTGCCTAAAAGAATCCTTCATACATCTTAAAGTTATCCTTTCCACACGCAGTATTCAGCAAGAGAATATTCTAATAATAGACAGTTTTGACAATATTTTGCACACTTCCTAAATTATATTTCTCCTAAGTAATTATATTTAAAAATCCAAACAATTTGATTTATAGTATTCTGGCTCAAAACCAGGCAGATGAGAAATTTATCTACCAGCTATATGGTTCCTCCAAATACCTGGGTAAAATTGAATTCCTCCTGTTTGAGTTGGAAGTTTAAGCTCAAAATCTAGTGATCTTTATAAATTGGGGGTATATTGAAAATGTGTATTTATATAAATGTATGTTTGATGTAAATAATTTATTCCAGTGTTACTGTTGCTTGAAGAATACTAGAAGTAACAAACACTATTTTGGGACTTTTTTGACAG
Seq C2 exon
GGTGACAGTGGGGGACCATTAATGTGCTACTTACCAGAATATAAAAGATTTTTTGTAATGGGAATTACCAGTTACGGACATGGCTGTGGTCGAAGAGGTTTTCCTGGTGTCTATATTGGGCCATCCTTCTACCAAAAGTGGCTGACAGAGCATTTCTTCCATGCAAGCACTCAAGGCATACTTACTATAAATATTTTACGTGGCCAGATCCTCATAGCTTTATGTTTTGTCATCTTACTAGCAACAACATAAAGAAATTCTGAAGGCTTTCATATCTTTATTTTGCATTGTGTCCCTTTCTATGTTCTATATAATGAACATCATTTATTCTTCTAGCAATTAATTGCCTACATTAGAGATTTCATGTGAACATTTTATGGGCTATAAGTATTGTGACAGATATACAATTGTAATTTTGGCACTGAATCACATGTCTCCTTGAAATATCTTGATTATTTTATAATCATAATTCTGTATCTGGAATACTCATAGAGTTTGTACAAAATATTCAGTTAAACATATATTTTATGTGTATAAATGCCAAATAATAGTTTATAATTAAAATGAAAGCTGTCATTTGGTTAAATTAATAAAAATTCTTTCTTAGATTTTATTCTAA
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000186452-TMPRSS12:NM_182559:4
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
Alternative protein isoforms
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0008921=Trypsin=PD(25.0=45.2)
A:
NA
C2:
PF0008921=Trypsin=PD(19.9=56.0)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal4)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TGCAGGTGATGAAGATGGAGC
R:
ACATAGAAAGGGACACAATGCA
Band lengths:
342-2215
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)