HsaINT0169721 @ hg38
Intron Retention
Gene
ENSG00000160183 | TMPRSS3
Description
transmembrane protease, serine 3 [Source:HGNC Symbol;Acc:HGNC:11877]
Coordinates
chr21:42383033-42384013:-
Coord C1 exon
chr21:42383970-42384013
Coord A exon
chr21:42383199-42383969
Coord C2 exon
chr21:42383033-42383198
Length
771 bp
Sequences
Splice sites
5' ss Seq
CAGGTAAGA
5' ss Score
10.77
3' ss Seq
GCCTTTGTTCCCCTCCATAGCCT
3' ss Score
10.41
Exon sequences
Seq C1 exon
GGAGGGATGTGCCTCTGGCCACGTGGTTACCTTGCAGTGCACAG
Seq A exon
GTAAGAGTTCCAGAAAGGCAGGGGTCCAGGGGGAGCAAGCACATGCTAAGTCCTATCTCCTTGCCCTCAGAGTCCTCTCCCCCCATGGGGCTCTGTATCCCTTCCTCCTGGGTGCCAGGCGGGAACTCTGTGTACCCCTACCTGCTGGAGGAGGGGAGCAGTGTCATCCTCACCTGTCGGCCTCACCTGTCAGGTGGGGGAGACAGCCAGAGCAACTCATTAGCAGCGGACAGGACCAAGGCCCATGATGTCCCATCACTCTGAAGAGCCTTGAGTCCCTGACTCAGTTCCCACTTCCTCCTTACACGTGCACAGTGCCCACTCCAGGCCTCGGGCAGTGCCCCTCGTTCCTGGCAGAGGGGAGTGTTCACACCACAAGGGTGGGGTCTGGAGCAGTCAGGGAGGTGCGTGCACCAGCGGCAGTGAGGAGGGGGCTGCAGAAGGTTCCTGCCTGCTCCTGACATCCCAGGGTGTTGTCATCACTGGGGGAATAGGATGGGGAGTGGTGCTGCCAATGCTGGGCACTGACCAAGCAGGGCAGGTGCTTTTCCCACCGCATCCTCCACAGCACCCACCATCCTCAGGTCTCCCCAAGAGCCTGACCACCTCCCCTGCTGAGCTCCCCCTTGCAGCACTTGTCTTAGAGCTGCTGTGAGCTCTGGGAGCAGGGGCAGTGAGGGTGGGGAGAGAGGAGCAGGTGCATGGTGGTGACACCATGTCCCCCAAAGAAGTCTGCAGGGTGGACCCACAAGCCTTTGTTCCCCTCCATAG
Seq C2 exon
CCTGTGGTCATAGAAGGGGCTACAGCTCACGCATCGTGGGTGGAAACATGTCCTTGCTCTCGCAGTGGCCCTGGCAGGCCAGCCTTCAGTTCCAGGGCTACCACCTGTGCGGGGGCTCTGTCATCACGCCCCTGTGGATCATCACTGCTGCACACTGTGTTTATGA
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000160183:ENST00000291532:7
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF154941=SRCR_2=FE(15.0=100)
A:
NA
C2:
PF154941=SRCR_2=PD(5.0=8.9),PF0008921=Trypsin=PU(19.3=78.6)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GGAGGGATGTGCCTCTGG
R:
TCATAAACACAGTGTGCAGCAGT
Band lengths:
210-981
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains