HsaINT0174180 @ hg19
Intron Retention
Gene
ENSG00000123607 | TTC21B
Description
tetratricopeptide repeat domain 21B [Source:HGNC Symbol;Acc:25660]
Coordinates
chr2:166767837-166769134:-
Coord C1 exon
chr2:166769024-166769134
Coord A exon
chr2:166767976-166769023
Coord C2 exon
chr2:166767837-166767975
Length
1048 bp
Sequences
Splice sites
5' ss Seq
ATGGTAAGT
5' ss Score
11.01
3' ss Seq
ATGGAATGAATTTTGTTTAGGCA
3' ss Score
2.39
Exon sequences
Seq C1 exon
CCTGAAGAAGCCATAGTAGCATATGAGCAAGCATTAAATCAGAACCCGAAAGATGGAACATTGGCAAGCAAAATGGGCAAAGCACTTATCAAAACTCATAACTACTCAATG
Seq A exon
GTAAGTACTTTATTGTTTGAAATATGTCTGTTGCATCAAATTTATCATACCCTGTCCTCGAGAAGCTTCAGCGAGCACCATTTGCATCTTTAATGGTTGTAAACTCCAAATCTGTATTTATGAACTGGGATTTGTGTTAAAGGCCTTCTTAGATTTATCAGATTCTTCATTGCTTCATTTCGTGGTGATTATTTGGACCCTAGACCTTGCTTCATCTTGCAGCTAGAATCCTTGCTACCAAATCAATTACCATAAAGTTGCTATTCTTACACCTCTTTCATTGTGTAACAAAACATGATAAATGTTCTTTCTGTTGCACCAATTTTTGCAAGCTATGTGTTTTGAGTTCATTTTTTTTTCCAGTAAGGGAAACAGATTTTTCTTGAACTGTTATATTCTTGCCCTATTCCTGGTAATTGTTGACCATATGTACAACAGCTAGCAAAATGTATGCCTTTGATAAGGTTCACTGGCCTCATAAAACCTGTAAAAAATATTCTTTGCCAAGTACCGTTCTTTATCTACTTATCATAAGAAATGTTAGTTGTTGGCCAGGTGTGGTGGCTCACGCCTGTAATCCTAACACTTTGGGAGGCCAAGACGGGTGGATCAATTGAGTTCAGGAGTTTGAAACCAGCCTGGCCAACATGGTGAAACCCCATCTCTACGAAAAAATACAAAAAATTAGCTGGGCATGGTGGTGGGCTCCTGTAATCCCAGCTACTTGGGAGGCTGAGGCAGGAGAATTGCTTGAACTTGGAAGGCAGAGGTTGCAGTGAGCTGAGATTGCATCACTGCACTCCAGCCTGGGTGATGGAGTGAGACTGTGACTCAAAAAAAAAAAATATATATATATATTAGTTGTTTCATGTGATGATCTATTCTCTGAGAAGTATGACATACTTAATTGACAGGCAGGTGTATGCCTACAATTCTTCCTGGTTATTTCTAGTTATACCAATGCTTTAAGTCTGTAATGTATTAAATAGCTCTGCTTGAATGCCATTCTCATTGCCTTGTTCCCTTAAATGGAATGAATTTTGTTTAG
Seq C2 exon
GCAATCACTTACTATGAAGCTGCTCTGAAAACTGGACAAAAGAATTATCTTTGCTATGACCTGGCTGAGCTCTTATTAAAATTGAAATGGTATGACAAAGCAGAAAAAGTTCTTCAGCATGCTCTGGCTCATGAACCTG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000123607-TTC21B:NM_024753:17
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF134141=TPR_11=FE(53.7=100)
A:
NA
C2:
PF134141=TPR_11=PD(16.4=23.4),PF134241=TPR_12=PU(44.9=74.5)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CCTGAAGAAGCCATAGTAGCA
R:
TTCATGAGCCAGAGCATGCTG
Band lengths:
246-1294
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)