HsaINT0175999 @ hg19
Intron Retention
Gene
ENSG00000130985 | UBA1
Description
ubiquitin-like modifier activating enzyme 1 [Source:HGNC Symbol;Acc:12469]
Coordinates
chrX:47065347-47065843:+
Coord C1 exon
chrX:47065347-47065512
Coord A exon
chrX:47065513-47065646
Coord C2 exon
chrX:47065647-47065843
Length
134 bp
Sequences
Splice sites
5' ss Seq
CCCGTGAGT
5' ss Score
8.4
3' ss Seq
TCGCTTTGTGCTCCCCACAGGCA
3' ss Score
10.34
Exon sequences
Seq C1 exon
AAGTTAAAGTCTGACACGGCTGCTGCAGCTGTGCGCCAAATGAATCCACATATCCGGGTGACAAGCCACCAGAACCGTGTGGGTCCTGACACGGAGCGCATCTATGATGACGATTTTTTCCAAAACCTAGATGGCGTGGCCAATGCCCTGGACAACGTGGATGCCC
Seq A exon
GTGAGTTTGGAGGCGGGTGAGGTGGTCACGGGCAAAGTTGTGTGTGTTTCGGTGTGTATATACCAAGAGGGGTGTCCGTCTTTCTGTCCTCTCCTGATGTTTCTTTCCTAGCTCTCGCTTTGTGCTCCCCACAG
Seq C2 exon
GCATGTACATGGACCGCCGCTGTGTCTACTACCGGAAGCCACTGCTGGAGTCAGGCACACTGGGCACCAAAGGCAATGTGCAGGTGGTGATCCCCTTCCTGACAGAGTCGTACAGTTCCAGCCAGGACCCACCTGAGAAGTCCATCCCCATCTGTACCCTGAAGAACTTCCCTAATGCCATCGAGCACACCCTGCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000130985-UBA1:NM_003334:15
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.241 A=NA C2=0.015
Domain overlap (PFAM):
C1:
PF0089916=ThiF=FE(37.9=100)
A:
NA
C2:
PF0089916=ThiF=PD(20.7=45.5),PF105854=UBA_e1_thiolCys=PU(73.3=50.0)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CAGCTGTGCGCCAAATGAATC
R:
CGACTCTGTCAGGAAGGGGAT
Band lengths:
251-385
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)