HsaINT0179934 @ hg19
Intron Retention
Gene
ENSG00000160293 | VAV2
Description
vav 2 guanine nucleotide exchange factor [Source:HGNC Symbol;Acc:12658]
Coordinates
chr9:136650898-136653608:-
Coord C1 exon
chr9:136653476-136653608
Coord A exon
chr9:136651008-136653475
Coord C2 exon
chr9:136650898-136651007
Length
2468 bp
Sequences
Splice sites
5' ss Seq
AAGGTGGGG
5' ss Score
5.87
3' ss Seq
GGCCCCTCTCCCCCCTGCAGTGG
3' ss Score
9.11
Exon sequences
Seq C1 exon
GTACTTGTTCCTGTTTGACAAGGTGGTCATCGTCTGCAAGCGGAAGGGCTACAGCTACGAGCTCAAGGAGATCATCGAGCTGCTGTTCCACAAGATGACCGACGACCCCATGAACAACAAGGACGTCAAGAAG
Seq A exon
GTGGGGCCTTCCGGGTCCCCCCTGCTACCCAGGAACGTGGGGGTGGCCTGGAGAGAGGCACTGGGTTCCAGACCCCAGGGGAAGGGGACTCGAAGTCAGCCGCTGATGCTGGCCGGGTGGGTTGGGGTGGGCGTCTCCGCTCTGCAGGAAGGCTCCTCTCTGAGTCACTGCCTCGCCGTCGTGACCACTGCTCATAGCAGGCCTGCTCCTCGCCGGGCCCAGCGCCCCCCAGAAAGGTGGGCAAGACCAGAATCCCACTCCCCAGTGAGGCGACTGAGGCAGAGGGGAGAGGCCACCCCAAGGCCTCTAGTGAGGGTGGGACTTTCAACCTTGGCTTTCCATCTGGCCAGCCTGACTCTAGCCCATGTTGTCCCTTGTAGCAAGCAGGCTTTCCTCTCCCGTCCCACCCTGCGGTGCTTGGAGGAGGGCTGTGGGTAGGTCTGGCTGTGGCTTGTCCGAGACTCTACATGTAGCTGGCTGGGGCCTGTGGCTGCTGGGGTGGGGCCAGGGCTGCAGGGGTGGGGCCTGTGGCTGCTGGGGCGGGGCCAGGACTGCAGAGGTGGGCCTGTGGCTGCCAGCGGGTGGGGCCAGGGCTACAGGGACGGGGCCGAAGCTGCTGTGGGGCAGGACCATGGCTATAGGGCTATTGCTGGCTGGCTGTCTGGTTCAGTCCTGCTTCAGCTGAGGCTTCTGCCCATGGCACTTGAGCAGCTACCGTGTGCAGCCCTGGTGGGGTGGGGGGCGGGGGTCAGGAGCCCTTGTTCTGAAAGTCCAGTCCCTGGCCTCCAGGGCTGGCAGTGTAGCCCTCGTCCAGACCCAGCAAGTGCAGACTGGATGAGCTGTTGAGGGTGACCCTCCCTGCCCTCATGCCCAAAACAAGTAACTGGGGCCCATGAGGCAGTCCTGCCACCAGCACCCAACACTCTGGGAAGAAATTCCTTTCCCCACTGATCACCCCACCCCCAGCCTGGGCACTGGGGGGTGTTCCACCTGCCAGGGCTCCTGGCGCCTCCACACTGCGGCACCCACCACAGGGCCGGGCTTAGCCTCTCACTGACCGTCTTCCCCTTCCTCTCCTCTCCATGCTTCCTAGTCTCACGGGAAAATGGTAAGCACCTAGCGCCCAGGTCCTCCCACCTGCCTCAATCATCCCAGCCTGGTGCTGGCACTTCTGCCCGGAGCCAGGGGACCCAGGGGCCTGAGGGGCTGGGCTCAGGGTTTTCTTGGTCCTTCGTCCTCCACTCCCTTTCCCGATGATGAAATGATTTGTATTCATGATGAAAGGCTTGCCCGCTAAGACAGTGTGAAAGGAAAACTCCGTGATCCTCAGTCCCTGGAGCTCGGGGTCAGAGGCTGGGGTTTCTTGGTCTCTCTTCAGCTCTCCATCATCCTTTTTGTTTTTCTGTGTTCTCTCCCTCCTCCCTCCCTCTTTCTCCCCTTTTCCTCTCTCTTTCCTTGTTTCTTTCCTCCTCCCATCCCCGCTCCACGCTTCCCCTCTCCATCCCTCCCTTCGTTCCTCTTTCCCGCCATCTTTTCTAACCCAGTAGGCTCCTATTTGCCAAACTCTTTTTTCTGGACCACTTTGAAAGCCCTTTGTCCGAGAGCTCGGAGAGATGGCGAGGCCTGTGGGGTGGCCGAAGGGGAGGCAGGGAAGGGGGCAGTTGTGGGTTGCTCAGTCGGGGATGGCTTCACGGGGGGTGCCCCAGGCCCATGGCTGTTCCCTGCCTTTTTGTTGTTACTGTTCTACTTCAGAGAAGTGAGGTTTTTTTAGCATCACATTTAGGAAGTGAAAGTGGGTGGTCAGGCCTCGTGGAGGGGCCCTGGGTGGGGCCCTGCGCTCATCCTTCCTGGGATCCTGCCCCCGCTTAACATGCATCTACATATGCACTCGGTGGAGCATCCTCGCACATGGGCGCAGGCAGGAGTGCAGACCTGCCCAGGCATGTGTGTGTGCACCCACAGGAGAGCACCCACAGGAGAGCACACACAGGAGAGCACCCACAGGAGAGCTCACACAGCATGGGTGCATGTGCATCATACGTGTTAGTACATGTGTGTACCTGCAGGGACAGATACAAGTGTGTGTGTGCACATGCTCACAGGAGCACTGGGCACACTCATGCACAGGTGCACACGCATAGACACGCGTGCAGGCACAGATGCACACCCATGCACGCAGGAGCACACTAGTATGCATGCAGAGGTGAAGGCACAAGCGCATATGTATTCTCACGTGAGGGTATGGGCACACAGCTATACATGCATGCATACAGAGGCACGTGTGCACGTACAGCATGGGCAAGAGAGCAGGTACACACGTGAGAACATGTGTTCACACAGGCACAGGCACCTGTGCACATATGCATATACACACGTGCACATGCTGCACAGGCGAGAGTACACGTGGACATGTGCCAGGATGTCTGAAGCCGTGTCTATTGCAAGCATGGCCCCTCTCCCCCCTGCAG
Seq C2 exon
TGGTCCTACGGCTTCTACCTAATTCACCTTCAAGGAAAGCAGGGCTTCCAGTTTTTCTGCAAAACAGAAGATATGAAGAGGAAGTGGATGGAGCAGTTTGAGATGGCCAT
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000160293-VAV2:NM_003371:14
Average complexity
IR-C
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.006 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0016924=PH=FE(41.1=100)
A:
NA
C2:
PF0016924=PH=PD(26.7=86.5)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)